论信息市场环境下的图书馆营销观

分析了信息市场的发展对图书馆信息资源建设、信息技术的开发以及信息传播方式和获取手段所产生的影响，探讨了面对激烈的市场竞争图书馆引入营销观念的必要性，并对具体的营销策略做了详尽的阐述。     

Cell surface heparan sulfate proteoglycans and lipoprotein metabolism

Cell surface heparan sulfate proteoglycans are involved in several aspects of the lipoprotein metabolism. Most of the biological activities of these proteoglycans are mediated via interactions of their heparan sulfate moieties with various protein ligands, including lipoproteins and lipases. The binding of lipoproteins to heparan sulfate is largely determined by their apoprotein composition, and apoproteins B and E display the highest affinity for heparan sulfate. Interactions of lipoproteins with heparan sulfate are important for the cellular uptake and turnover of lipoproteins, in part by enhancing the accessibility of lipoproteins to lipoprotein receptors and lipases. Apoprotein B may interact with receptors without involving heparan sulfate. Heparan sulfate has been further implicated in presentation and stabilization of lipoprotein lipase and hepatic lipase on cell surfaces and in the transport of lipoprotein lipase from extravascular cells to the luminal surface of the endothelia. In atherosclerosis, heparan sulfate is intimately involved in several events important to the pathophysiology of the disease. Heparan sulfate thus binds and regulates the activity of growth factors, cytokines, superoxide dismutase and antithrombin, which contribute to aberrant cell proliferation, migration and matrix production, scavenging of reactive oxygen radicals and thrombosis. In this review we discuss the various roles of heparan sulfate proteoglycans in vascular biology, with emphasis on interactions of heparan sulfate with lipoproteins and lipases and the molecular basis of such interactions.     

水稻枝梗数性状的遗传研究进展

水稻穗部枝梗教影响稻谷产量.就穗部一、二次枝梗数性状的遗传研究进行了综述.研究表明枝梗数是受多基因控制的数量性状,具高的遗传力和变异度,其基因的表达受水分胁迫、不同年份的影响,并存在基因间上位性以及基因型与环境间互作;枝梗数与稻谷产量呈正相关:在早期世代和高代分别对一次枝梗数和二次枝梗数进行选择有较好效果.     

L(p)(p>1)‖f‖_p与E_f(p)中的连续性

证明 了 Ｌ （ｐ）（ｐ＞ １）中‖ ｆ‖ 与 Ｅ （ｐ）关 于 ｐ 的 连续 性 ，即 ：当 ｐ０＞ ｐ＞１，ｆ（ｘ）∈ ｐ ｆＬＰ （Ｅ ）时 ，ｌｉｍ ‖ ｆ‖_ｐ ＝‖ ｆ‖_Ｐ ，ｌｉｍ Ｅ （ｐ）＝Ｅ （ｐ０）。 ０ ０ ｆ ｆ ｐ→ｐ０ ｐ→ｐ０     

采用图像信息学方法研究三维支架中细胞的信号通路

通过慢病毒介导的短发夹RNA对成纤维细胞的转化生长因子β(TGF-β)信号通路进行干扰,采用双光子荧光显微成像技术并结合基于细胞-细胞外基质三维系统的图像信息学方法,研究了植于多孔胶原蛋白支架中成纤维细胞分化过程的TGF-β信号通路.结果表明,在介导成纤维细胞分化的过程中,生长因子TGF-β1比TGF-β3发挥的作用更大,在TGF-β1介导的成纤维细胞分化过程中,蛋白SMAD1和SMAD3通过不同方式也发挥了重要作用.所得结果与通过生化或遗传学方法的结果相吻合.     

输液瓶的吸附作用对胰岛素输注过程中浓度变化的影响

为了解胰岛素注射液在输液过程中的浓度变化情况,指导临床合理操作,模拟了临床胰岛素配液以及输注操作过程,实验分为玻璃瓶组和塑料瓶组,各组又按操作的不同分为输液组和吸附组.采用紫外分光光度法测定胰岛素浓度.输液组流速为50滴/min,每输注50 mL液体取样测定胰岛素浓度.吸附组按溶媒不同分为氯化钠组、50 g/L葡萄糖组和100 g/L葡萄糖组,每隔10 min轻轻振摇1次,并取液测定浓度.结果表明,不同材质和装有不同溶媒的输液瓶对胰岛素的吸附趋势类似,但塑料瓶对胰岛素的吸附量大于玻璃瓶,装有氯化钠的输液瓶大于葡萄糖输液瓶,100 g/L葡萄糖输液瓶大于50 g/L葡萄糖输液瓶.因此,在胰岛素输液过程中,应考虑到输液瓶对胰岛素的吸附导致的药量损失.     

Serglycin – Structure and biology

Serglycin is a proteoglycan found in hematopoietic cells and endothelial cells. It has important functions related to formation of several types of storage granules. In connective tissue mast cells the covalently attached glycosaminoglycan is heparin, whereas mucosal mast cells and activated macrophages contain oversulfated chondroitin sulfate (type E). In mast cells, serglycin interact with histamine, chymase, tryptase and carboxypeptidase, in neutrophils with elastase, in cytotoxic T cells with granzyme B, in endothelial cells with tissue-type plasminogen activator and in macrophages with tumor necrosis factor-α. Serglycin is important for the retention of key inflammatory mediators inside storage granules and secretory vesicles. Serglycin can further modulate the activities of partner molecules in different ways after secretion from activated immune cells, through protection, transport, activation and interactions with substrates or target cells. Serglycin is a proteoglycan with important roles in inflammatory reactions. Received 2 October 2007; received after revision 7 November 2007; accepted 12 November 2007     

直线永磁振动电机的磁场与静推力特性分析

主要介绍了一种直线永磁振动电机的结构及其工作原理，并用有限元软件对其在不同位置时的磁场进行了分析，同时搭建实验台做了实际的测试，给出了误差及出现误差的原因。该电机结构简单，可靠性高，寿命长，易维护，并且控制电路简单，运行平稳，适用于小功率电磁间的开关系统中。     

低成本MEMS磁力计校正方法研究

基于MIMU(magnetic and inertial measurement unit)的人体动作捕捉技术,每个测量单元在使用前,均需要对其磁力计进行校正.然而,一套人体动作捕捉系统具有7至十几个MIMU,因此缩短MIMU中磁力计校正的总时间是亟需解决的关键问题.磁力计校正可采用的旋转形式主要有两种,分别为八字旋转的校正方法和绕着各单轴旋转的校正方法.为了节省磁力计的校正时间并保证磁力计的校正精度,提出了一种优化的校正方法.即采用最小二乘法的椭球拟合方法,根据求得的椭球模型原点和半径均方根误差,确定最佳的旋转形式和旋转次数,以较快、较准确地校正磁力计.实验结果表明,绕各单轴各旋转1次的校正方法效果最佳.