纳米硒的功能设计及其在肿瘤精准治疗中的应用进展

 纳米硒作为一种新型单质硒，与有机硒和无机硒相比具有更高的生物利用度，更强的生物活性和更低的毒性，并且具有抗氧化和抗肿瘤的作用。概述了纳米硒在生物医药中的应用，包括纳米硒用于化疗、放疗、放化疗以及其他临床药物的增敏，纳米硒的功能化和靶向修饰增强抗肿瘤效果，含硒纳米材料在抗肿瘤中的应用，纳米硒的毒理学，介绍了纳米硒制剂产业化发展情况。     

微生物废水处理产甲烷的自动控制系统

结合现代的自动控制技术和互联网技术,设计了基于微生物废水处理产甲烷的自动控制系统.选用基于Cortex A9主控芯片的Exynos4412作为控制核心,使用云架构的tomcat服务器进行数据存储,配合现场工业级执行单元与标准专用传感器,实现了微生物培养进而处理工业废水以及提高甲烷生产含量的目标.实际运行结果表明:该系统成功将废水处理至排放标准并使得生产的甲烷含量由52%提升至77%,具有较高的实用价值和应用推广价值.     

基于改进多目标布谷鸟算法的污水处理优化控制方法

针对如何确定污水处理优化控制中关键变量的最优设定值,以满足出水水质达标的同时尽可能降低能耗的问题,提出一种基于改进多目标布谷鸟算法的污水处理多目标优化控制方法.首先,通过对污水处理过程的分析,建立基于神经网络的污水处理能耗和出水水质模型;其次,利用改进多目标布谷鸟算法同时对污水处理能耗和出水水质模型进行优化,得到溶解氧和硝态氮浓度的优化设定值;最后,利用PID控制器对关键变量的最优设定值进行跟踪控制,实现污水处理过程的多目标优化控制.仿真实验结果表明,与其他几种方法相比,所提出的方法在保证出水水质参数达标的前提下,更好地降低了污水处理过程的能耗,实现节能降耗和保护环境的目的.     

Microstructure and heat treatment for Ni3Al-based single crystal alloy with different crystal orientations

Ni₃Al-based single crystal alloy IC6SX with different crystal orientations were prepared by seed crystal method. The microstructure and heat treatment of the alloy were investigated. The results showed that the microstructure of the alloy was in dendrite structure, and the crystal orientation had significant effect on the dendrite morphology of this alloy. The precipitated phases of (MoNi)₆C and NiMo appeared in the microstructure of the three alloys with different crystal orientations during solidification process. Compared with other two alloys, the volume fractions of precipitated phases of both (MoNi)₆C and NiMo was the most in the alloy with [111] orientation and the least in the alloy with [001] orientation. The solidus and liquidus temperatures of the alloy IC6SX tested by differential scanning calorimetry (DSC) were 1356 °C and 1387 °C, respectively. Meanwhile, the effect of different solution temperatures on the microstructure of the alloy with different orientations was studied. The results showed that the precipitated phases of (MoNi)₆C and NiMo were eliminated with the solid solution treatment under the condition of 1300 °C/10 h. However, the incipient melting of the alloys occurred due to the dissolution of low melting point phases. As the temperature dropped to 1280 °C, the area of incipient melting in the alloy with different orientations decreased gradually. However, there was no incipient melting appearing in the three alloys with different orientations when the solution treatment temperature dropped to 1260 °C.     

纳米Al2O3介导的固定化小球藻燃料电池产电性能分析

采用纳米Al2O3 海藻酸钠联合固定化制备小球藻胶球，并应用于微生物燃料电池阴极，以提供电子受体，考察电池的产电性能。研究结果表明:加入纳米Al2O3能提高海藻酸钠固定化小球藻胶球的比表面积，使固定化小球藻阴极MFCs输出电压由0113 V提高到0173 V，且电池的输出电压随着胶球粒径的减小和加入量的增加而提高，光照可降低MFCs内阻，提高产电性能。     

结肠息肉内镜下治疗的体会

目的:探讨结肠息肉内镜下治疗的各种方法及效果.方法:通过肠镜检查8 024例确诊的各种形态、大小息肉1 326例共1 637颗,对于不同大小、形态的息肉,采用单一和联合的内镜治疗.结果:1 326例结肠息肉内镜治疗1 637颗,其中有4例因基底癌变转外科治疗,发生迟发性出血9例,再次内镜下止血成功;穿孔2例,1例钛夹修补成功,1例钛夹修补失败转外科治疗,并发症发生率为0.82%.结论:结肠息肉内镜下治疗是一种安全有效的方法.     

一类具有转移和治疗机制的随机结核病模型的平稳分布与灭绝

考虑一类具有转移和治疗机制的肺结核传播模型在随机扰动下的动力学行为. 首先, 通过Lyapunov分析方法得到该模型正解的存在和唯一性； 然后利用Has’minskii理论证明该模型存在唯一的平稳分布； 最后通过随机分析方法得到该模型疾病消失的条件.     

FeCo-based hybrid MOF derived active species for effective oxygen evolution

Metal-organic frameworks(MOFs) have been regarded as promising catalyst materials due to the richness of coordinately unsaturated metal sites on the surface,which can act as catalytic active centres.In this study,a hybrid MOF material composed of Fe-based MOF and Co-based MOF was prepared with the involvement of graphene oxide nanosheets as additive.It was demonstrated that the hybrid MOF materials showed much higher electro-catalytic activity towards oxygen evolution than the single-phase counterparts.To drive current density of 10 mA cm~(-2),the hybrid CoFe-based MOF only needed an over potential of 290 mV in 1 M KOH.The catalytic activity could sustain for a longer time with only slight current density decrease.During oxygen evolution operation,the MOF catalyst evolved into catalytic active species but kept well the microscale sheet-like structure.It is thus believed that this study will provide an avenue for the development of advanced electrocatalysts.     

致密气藏中防水锁剂的筛选方法及其微观机理

致密气藏物性差，只有通过水力压裂才能获得工业产能。在压裂过程中，水相压裂液侵入储层后会产生水锁现象，对储层造成伤害，严重影响致密气藏的产量。在压裂液中添加防水锁剂可以有效降低水锁带来的伤害。为了揭示防水锁剂降低水锁提高产量的机理,本文以DME稀释微乳液为例，首先通过表面张力实验，测试了DME稀释微乳液的表面张力随浓度的变化关系，并得到最佳的添加浓度；然后通过接触角实验评价了DME稀释微乳液的改变润湿性作用；之后结合自发渗吸和渗透率恢复率实验证明了DME稀释微乳液的降水锁功能；同时借助核磁共振研究了渗吸过程中水相进入不同大小孔喉的顺序以及渗吸采收率。本文还建立了一种有效评价防水锁剂的方法，为现场施工筛选此类添加剂提供了指导。     

凋亡抑制蛋白与肿瘤关系的研究

凋亡抑制蛋白(inhibitor of apoptosis proteins,IAPs)可以作为癌症诊断和治疗的靶点,在肿瘤研究方面备受关注,就凋亡抑制蛋白的结构、功能、在肿瘤中的表达与肿瘤的关系等研究进展作一综述,为凋亡抑制蛋白的研究提供信息和思路.