虫草抗运动性疲劳实验研究

目的利用小鼠负重游泳实验,观察小鼠运动性疲劳时体内相关指标变化及其机制.方法 1)测定小鼠耐缺氧时间;2)测定肝(肌)糖原含量改变;3)测定鼠血中丙二醛含量变化.结果虫草能提高鼠耐缺氧时间;显著提高鼠肝(肌)糖原的储备;并能降低鼠血中丙二醛含量,并显示与剂量纯度关系.结论虫草具有明显的抗疲劳作用.     

Effect of protein kinase C activation and depletion on insulin stimulation of glycogen synthesis in cultured hepatoma cells

Summary Insulin stimulation of glycogen synthesis was nearly abolished in hepatoma cells shortly treated with 4 ß-phorbol 12 \-myristate, 13 -acetate (protein kinase C activation) but remained unmodified in cells chronically treated with the phorbol ester (protein kinase C depletion). Thus, although exogenous activation of protein kinase C results in an inhibition of insulin action, protein kinase C depletion has no influence on this process. The results suggest that, in hepatoma cells, no endogenous activation of protein kinase C may occur in response to the signal triggered by insulin.     

限食对树麻雀能量代谢及消化道形态结构的影响

为探讨限食对树麻雀(Passer montanus)生理生化指标和消化道形态的影响,按其体重随机分为对照组、半饥饿组和1/4饥饿组进行驯化,驯化结束后测定其生理生化指标和消化道形态变化.研究发现,随着限食程度的加大,半饥饿组和1/4饥饿组的体质量、基础代谢率(Basal metabolic rate,BMR)、体脂质量分数、糖原含量、消化道绒毛高度、宽度及肠壁截面积与对照组相比呈降低趋势,器官鲜质量、消化能、消化率、消化道长度呈升高趋势.表明限食是影响树麻雀消化道形态改变的重要环境因子之一;在限食条件下,树麻雀通过降低体质量,增加摄入能、改变消化道形态结构,消耗体内的能量储备和减少基础能耗来缓解食物短缺的生存压力.     

鞭角华扁叶蜂预蛹脂肪体和血淋巴中糖类含量动态

研究了鞭角华蜂滞育预蛹的糖类含量动态。结果表明，在滞育期间，鞭角华扁叶蜂滞有预蛹脂肪体糖原的含量呈下降趋势，血淋巴中海藻糖的含量则升高的趋势。在否育的前期，机体内糖原和海藻糖之间 存在明显的相互转化，并与滞育阶段和温度相关。雌性预蛹糖原和海藻糖的含量均高于雄性预蛹，但代谢趋势一致。     

Glycogenolytic effect of vasoactive intestinal peptide in the rat in vivo

Summary The effects of VIP (300 pmol/kg), injected via the portal vein, on the glycogen content of the liver and on glycemia, were studied in the rat in vivo. VIP enhanced glycogenolysis and caused hyperglycemia in a time-dependent manner.     

Glycogen synthase kinase 3: A key regulator of cellular fate

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified as a key regulator of insulin-dependent glycogen synthesis. GSK-3 was subsequently shown to function in a wide range of cellular processes including differentiation, growth, motility and apoptosis. Aberrant regulation of GSK-3 has been implicated in a range of human pathologies including Alzheimer’s disease, non-insulin-dependent diabetes mellitus (NIDDM) and cancer. As a consequence, the regulation of GSK-3 and the therapeutic potential of GSK-3 inhibitors have become key areas of investigation. This review will focus on the mechanisms of GSK-3 regulation, with emphasis on modulation by upstream signals, control of substrate specificity and GSK-3 localisation. The details of these mechanisms will be discussed in the context of specific signalling pathways. Received 30 January 2007; received after revision 5 March 2007; accepted 16 April 2007     

强化生物除磷工艺中聚磷菌和聚糖菌竞争影响因素的研究进展

强化生物除磷(EBPR)是一种高效、经济的除磷工艺,然而在某些条件下聚糖菌的过量繁殖导致除磷效果恶化。文章阐述了影响聚磷菌和聚糖菌生长的关键因素,并展望了今后的研究方向。