新疆棉藓属(Plagiothecium B.S.G.)植物的分类及新记录

棉藓属Plagiothecium是棉藓科(Plagiotheciaceae)中仅有的代表属,全世界约90种。我国记录16种、6变种和1变型。根据在全疆范围内收集及采集的60号标本的鉴定和近20年来前人有关新疆棉藓属的记录,现已知新疆共有棉藓属植物4种,其中3种为新疆首次记录:包括圆条棉藓Plagiothecium cavifolium(Brid.)Iwats.、棉藓P.denticulatum(Hedw.)Schimp.、小叶棉藓P.latebricola Schimp.。文中列出了分种检索表,并对各种作了主要特征描述。     

土大黄研究进展

 综述了土大黄古籍文献、临床应用及现代药理研究品种,发现土大黄古籍文献、临床应用品种较少,主要集中在羊蹄、尼泊尔酸模、钝叶酸模,用于止血、抗炎、治疗皮肤病。现代药理研究品种较多,其中羊蹄、巴天酸模研究最多,其次是钝叶酸模、皱叶酸模、尼泊尔酸模,具有抗菌、止血、保肝、降糖、抗炎、抗肿瘤、治疗皮肤病等作用。但仍缺乏药理研究相应的临床应用和古籍文献记载,临床应用部分单味药和大多复方制剂仍缺乏品种鉴定或品种标注。     

Comparative stability analyses of traditional and selective room-and-pillar mining techniques for sub-horizontal tungsten veins

The stability and productivity concerning a modification on the traditional room and pillar for a new selective technique at the Portuguese Panasqueira Mine have been described. The traditional room-and-pillar stoping uses 5.0-m wide rooms with 3.0 m×3.0 m pillars, while the selective room-and-pillar mining technique consists in stoping with rooms of 4.0 m wide and pillars of 4 m×4 m with a subsequent selective cutting of the quartz veins at the mid pillar of approximately 0.5 m high, to obtain a pillar section with an area of 3.0 m×3.0 m. The stability and productivity analyses indicate that the selective technique obtains smaller average pillar safety factor, more rock mass displacement, more extraction and selectivity ratios, and ore grade improvement, compared with the traditional technique. These results show that the selective technique is also more convenient. This proposed selective room-and-pillar mining technique is applicable to any sub-horizontal narrow quartz veins with wolfram, gold, etc. such as the famous La Rinconada gold mine in the Peruvian Andes.     

西帕依固龈液对IL-1β刺激人牙龈成纤维细胞产生PGE2的影响

 研究不同浓度西帕依固龈液对白细胞介素-1β(Interleukin-1β,IL-1β)刺激人牙龈成纤维细胞(Human Gingival Fibroblast,HGF)产生前列腺素E₂(Prostaglandin E₂,PGE₂)水平的影响。采用健康人牙龈组织原代培养的HGF细胞,以1ng/mL的IL-1β作为刺激因子,将HGF细胞按5×10⁴/mL的细胞密度接种到24孔培养板中,每孔200μL的细胞悬液。孵育24h贴壁后,弃原培养液,清洗2次后加药,分组为空白对照组(用含20mL/L的胎牛血清的DMEM培养液),IL-1β组(浓度为1ng/mL),IL-1β+西帕依固龈液组(西帕依固龈液终末浓度分别为12.5、25、50、100、200μg/mL),IL-1β+消炎痛(消炎痛浓度为100ng/mL)。用酶联免疫法测定PGE₂含量,观察不同浓度的西帕依固龈液(分别为12.5、25、50、100、200μg/mL)对HGF培养上清中PGE₂水平的影响。结果显示,5种不同浓度的西帕依固龈液均能显著抑制1ng/mL的IL-1β刺激后HGF产生PGE₂,随着浓度的增加,抑制效果也增加,但5种浓度的西帕依固龈液抑制效果均低于100ng/mL的消炎痛。由此得出,HGF具有合成和分泌PGE₂的功能,IL-1β能有效刺激HGF产生PGE₂;西帕依固龈液对IL-1β刺激HGF合成和分泌PGE₂具有显著抑制作用,其抑制作用在一定范围内呈浓度依赖性。     

钨合金精密磨削砂轮磨损及对表面质量的影响机制

为了满足钨合金零件的高精度和高完整性表面加工需求,实现钨合金磨削质量的控制和加工工艺的优化,通过分析砂轮磨粒种类和结合剂类型对砂轮磨损形式的关系,明确了超硬磨料砂轮在钨合金磨削加工中的优势.研究了磨粒粒度和磨削参数对钨合金磨削加工质量的影响规律,为制定合理的磨削工艺提供依据.通过磨削试验获得钨合金高精度和高完整性表面磨削加工工艺.研究结果表明,钨合金磨削过程中砂轮易磨损,超硬磨料砂轮更适合钨合金的磨削加工.金属结合剂金刚石砂轮在钨合金磨削加工的表面质量和加工精度方面表现出优越性.通过改进磨削参数,钨合金精密磨削后表面粗糙度可达18.9 nm,实现了镜面磨削效果.     

基于神经网络的光伏电站气象-功率模型

基于双层前馈神经网络建立光伏电站输出功率与辐照等气象因素间的非机理模型。建立光伏电站输出功率与气象因素的神经网络模型;对功率模型的输入特征进行选择,分析不同气象因素的组合作为输入变量对模型准确度的影响,明确功率模型的输入变量;分析该模型网络的训练算法、隐含层神经元个数及训练次数对模型准确度的影响,据此确定功率模型的最优结构与参数;基于光伏电站的实际数据对功率模型进行验证。结果表明,基于双层前馈神经网络的光伏电站气象-功率模型具有较高的准确度。     

基于区间解析冗余关系的参数不确定性研究

本文主要目的是拓展基于区间解析冗余关系法I-ARRs(Interval valued Analytical Redundancy Relations)对不确定性混杂系统的故障检测。该方法产生一组对故障估计的阈值,一旦标称残差超过阈值,则故障能被检测。现有的故障检测方法主要是针对参数性故障,因此对测量信号导数的估计呈现出各种限制。而且在I-ARRs中对测量信号导数十分敏感,这不可避免地涉及到对残差的估计。为解决这一问题,利用鲁棒滑模微分器方法得到对含噪声测量信号导数最优估计,降低残差噪声,以减小虚警、漏报,从而提高鲁棒性。通过典型电力电子电路BUCK电路仿真,验证了此方法的有效性。     

准噶尔盆地荒漠灌木林区利用天敌防控鼠害方法探讨

大沙鼠、子午沙鼠、三趾跳鼠是准噶尔盆地荒漠灌木梭梭林的主要危害生物,且种群数量和密度呈上升趋势。设立人工招引鹰、隼、鸮等天敌设施,为天敌提供觅食、栖息、繁衍的有效平台,既能够在一定范围内调控鼠群密度,又可起到增加荒漠区生物多样性和生态、经济、持续、有效防控鼠害的作用,进而达到保护荒漠植被、稳定荒漠生态、治理荒漠系统的目的。     

An aqueous extract of Liu Wei Di Huang Wan alters the labeling of blood constituents with Technetium-99m

The Liu Wei Di Huang Wan is a formula of a traditional Chinese medicine that is used to treat asthma patients and has been shown to have several important properties,such as antioxidant and free radical scavenging activities.The influence of an extract of Liu Wei Di Huang Wan on the labeling of blood constituents with technetium-99m was investigated.Anticoagulated blood(Wistar rats) was incubated with the extract,stannous chloride and technetium-99m,as sodium pertechnetate.Samples were centrifuged and aliquots of plasma and blood cells were separated and precipitated with trichloroacetic acid,to obtain soluble and insoluble fractions of the blood constituents.The percentage of radioactivity(%ATI) in all the fractions was determined.The analysis of the results shows that the extract at the highest concentration used(70 mg/mL) decreased significantly(P<0.05) the %ATI(from 96.48 ± 1.19 to 54.46 ± 7.38) on blood cells compartment,(from 81.11 ± 4.15 to 61.33 ± 4.74) on insoluble fractions of blood cells and(from 65.91 ± 2.44 to 13.15 ± 3.62) on insoluble fractions of plasma.In conclusion,the results suggest that the substances present on this extract can alter this labeling process,probably due to(i) redox properties(antioxidant and chelator activities) and/or(ii) specific actions in the binding sites where the 99mTc would be bound on the blood constituents.As a consequence,precaution is suggested on the interpretation of the nuclear medicine results from performed with blood constituents labeled with 99m Tc in patients that have undertaken LWDHW,although the current findings were obtained in experimental animal models.     

红斑丹毒丝菌C43065株spaA基因的克隆和表达

通过PCR从红斑丹毒丝菌C43065株基因组DNA中扩增出编码信号肽除外的成熟SpaA蛋白基因spaA,将其克隆到表达载体pET32a的BamHⅠ和Hind Ⅲ位点上,构建重组表达质粒pET-spaA,转化大肠杆菌BL21,在IPTG诱导下表达N端带有Trx标签的融合蛋白rSpaA,SDS-PAGE检测表达蛋白.DNA测序结果表明,spaA基因大小为1794 bp,编码由597个氨基酸残基组成的成熟SpaA蛋白,SDS-PAGE结果显示在大肠杆菌BL21中成功表达了分子量约为86 kDa的重组rSpaA,为进一步开展SpaA保护区域的研究奠定基础.