四川省旅游经济发展影响因素实证探究

基于2000—2016年四川省旅游经济数据,从地区宏观经济发展水平、旅游资源吸引力、旅游消费需求、旅游接待能力、交通便利程度等方面选取指标建立多元线性回归模型,对当地旅游经济发展进行实证分析。结果表明:显著影响四川省旅游经济发展的变量为国内旅游人次和居民消费水平。并针对目前存在的问题对促进四川省旅游经济更快更好发展提出合理建议。     

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

Hereditary pheochromocytoma (PCC) is often caused by germline mutations in one of nine susceptibility genes described to date, but there are familial cases without mutations in these known genes. We sequenced the exomes of three unrelated individuals with hereditary PCC (cases) and identified mutations in MAX, the MYC associated factor X gene. Absence of MAX protein in the tumors and loss of heterozygosity caused by uniparental disomy supported the involvement of MAX alterations in the disease. A follow-up study of a selected series of 59 cases with PCC identified five additional MAX mutations and suggested an association with malignant outcome and preferential paternal transmission of MAX mutations. The involvement of the MYC-MAX-MXD1 network in the development and progression of neural crest cell tumors is further supported by the lack of functional MAX in rat PCC (PC12) cells and by the amplification of MYCN in neuroblastoma and suggests that loss of MAX function is correlated with metastatic potential.     

延安新华广播电台传播技术与设备的发展

目的从技术和设备的角度探究延安新华广播电台成立的过程。方法历史辩证与分析。结果在新民民主主义革命中,从国民党部队吸收的一批无线电人才是延安新华广播无线电人才队伍中的重要组成部分;中央军委通信学校和延安通信材料厂的建立使延安新华广播电台实现了技术人才和无线电器材的自给;广播技术人才利用早期无线电通信技术在艰苦的环境下自主研发组装了一批广播技术设备。结论延安新华广播电台的建立开创了宣传工作的新阶段,反映了八路军信息化建设的肇始情况;延安新华广播电台的广播技术经历了一个从情报通信技术到口语广播技术和文字广播技术并存的发展过程,广播人才队伍经历了一个从业余到专业,从零散人员到具有一定规模人数的发展过程。     

Emerging topics and new perspectives on HLA-G

Following the Fifth International Conference on non-classical HLA-G antigens (HLA-G), held in Paris in July 2009, we selected some topics which focus on emerging aspects in the setting of HLA-G functions. In particular, HLA-G molecules could play a role in: (1) various inflammatory disorders, such as multiple sclerosis, intracerebral hemorrhage, gastrointestinal, skin and rheumatic diseases, and asthma, where they may act as immunoregulatory factors; (2) the mechanisms to escape immune surveillance utilized by several viruses, such as human cytomegalovirus, herpes simplex virus type 1, rabies virus, hepatitis C virus, influenza virus type A and human immunodeficiency virus 1 (HIV-1); and (3) cytokine/chemokine network and stem cell transplantation, since they seem to modulate cell migration by the downregulation of chemokine receptor expression and mesenchymal stem cell activity blocking of effector cell functions and the generation of regulatory T cells. However, the immunomodulatory circuits mediated by HLA-G proteins still remain to be clarified.     

Photo-physical Characterisation of Novel Organic Dye-doped Solid-state Laser Materials

1 Results The development of tuneable solid-state organic dye lasers is a subject of considerable interest and research activity.Compared to conventional liquid dye lasers they have the advantage of being free of solvent handling,having small size,and being easy to operate.For high-performance solid-state dye lasers highly photo-stable dyes with low quantum yield of triplet formation and low triplet-triplet absorption cross-section in the lasing wavelength region are required.For solid state dye lasers organic molecules have been incorporated in inorganic glasses (mainly sol-gel glasses),in organic polymer matrices,and into hybrid compositions of inorganic-organic hosts.Here samples of the BODIPY dye (dipyrromethene-BF2 dye) PM597 incorporated in copolymers resembling inorganic-organic hybrid matrices are characterized by optical spectroscopic methods towards their application as solid-state laser rods.The inorganic function is entered by the constituent 3-(trimethoxysilyl)propyl methacrylate (TMSPMA).The organic constituents are monomers with one polymerizable group [methyl methacrylate (MMA),or 2-hydroxyethyl methacrylate (HEMA)],two [ethylene glycol dimethacrylate (EGDMA)],three [pentaerythriol triacrylate (PETA)],and four [pentaerythriol tetraacrylate (PETRA)] polymerizable groups.The copolymers were obtained by radical bulk polymerization with 2,2'-azobis(isobutyronitrile) (AIBN) as polymerization initiator.TMSPMA and MMA were also copolymerized by "in-situ" and simultaneous hydrolysis-condensation of the methoxy groups of TMSPMA during the free radical polymerization of MMA using AIBN in order to fully approach a sol-gel inorganic glass-organic polymer hybrid solid-state dye laser material.Structural and thermo-mechanical studies (thermogravimetry,differential scanning calorimetry,and infrared spectroscopy) revealed the highest thermo-mechanical stability for high-degree inter-crossing copolymerisation [COP(TMSPMA-PETA),COP(TMSPMA-PETRA)] and hydrolysis-polymerization [COPH(MMA-TMSPMA)].Concerning the optical spectroscopy characterisation,all studied PM597 doped copolymer samples exhibited high fluorescence quantum yields (60 % to 70 %),negligibly small excited-state absorption cross-sections (5% to 10 % of ground-state absorption at 527 nm),and high photo-stability (typically up to 3 million excitation cycles before degradation after some initial fading).The laser properties of the PM597 doped copolymers were evaluated by transversal pumping with 6 ns laser pulses of 5.5 mJ energy at 532 nm.Most of the studied samples surpassed 100 000 laser shots with no or only less than 50 % of laser output power reduction.     

What is Going on in a Critical Thermosyphon?

IntroductionWell- known optical phenomena in fluids in thethermodynamic critical state are the disappearanceof the meniscus between liquid and vapour phaseand the existence of a“critical opalescence”.　 This opalescence is observed as bluish inreflected…     

Hyperbranched Organometallic Polyynes :Optical and Thermal Properties and Their Transformation into Soft Ferromagnetic Ceramics

1Introduction Organometallic polymers have emerged as a group of interesting materials due to their useful catalytic,optical, electrical, sensing, and magnetic properties inaccessible by their pure organic parents. It is therefore highly desirable to utilize this class of high performance macromolecules for the preparation of micro- and nanosized patterns by photolithographic techniques and as precursors for advanced ceramics[1].     

一类复杂非线性过程的广义一般模型控制

介绍了一般模型控制（ＧＭＣ）的基本原理,给出了ＧＭＣ方法简单实用的必要条件。针对ＧＭＣ方法只适于相对阶ｒ为１的简单过程的缺点,采用Ｌｉｅ导数的概念,令过程输出的ｒ阶导数的轨迹为事先设定的标称轨迹,通过解优化问题得到控制律表达式,把ＧＭＣ方法推广至相对阶ｒ大于１的复杂多输入多输出过程,从而提出了一种广义一般模型控制（ＧＧＭＣ）方法。仿真结果表明,提出的方法能应用于相对阶ｒ大于１的复杂非线性过程的控制,当采用线性近似模型时,其控制性能与模型预测控制（ＭＰＣ）相近,而计算量则有所降低。     

钢轨在线热处理过程同步逆模控制系统研究

目的控制钢轨在线热处理过程中钢轨头内的分布参数温度,使钢轨头等温转变为均匀的细珠光体组织。方法①将钢轨热处理过程中的分布参数温度系统处理成集中参数温度模型,并用逆模型控制方法进行控制;②采用对钢轨表面温度进行偏离度补偿的方法来测量钢轨集中参数温度;③提出了单元冷却器控制信号的切换速度与钢轨的运动速度一致的同步切换控制方法。结果表明初始温度在620~820℃随机分布的60 kg/m2碳钢轨,6 s后钢轨断面平均温度偏差可以控制在±10℃范围内,符合实际工艺条件;解决了钢轨在线热处理中金相组织均匀等温转变的控制问题以及钢轨首尾温差和通长温度分布不均的控制问题。结论钢轨的等温转变温度是最重要的被控参数,等温转变温度越低,处理后的钢轨硬度越高。     

X70管线钢焊接接头组织及其海水腐蚀规律

对X70管线钢现场实际焊接工艺下的焊接接头,采用显微镜、电化学方法及失重法等方法和手段对母材、焊缝、热影响区进行了显微组织分析和在海水中的极化曲线、腐蚀速率的测试,研究焊接接头在模拟海水环境中的腐蚀性能。研究表明,X70管线钢焊接接头各区域组织不均匀,实验室模拟海水环境下的电化学行为、腐蚀速率存在明显差异;在海水腐蚀过程中腐蚀电位和腐蚀速率会发生变化,热影响区（HAZ）与母材及焊缝形成电偶腐蚀,接头腐蚀以点蚀为主。