乳癌根治术中复合静脉麻醉与硬膜外麻醉的比较

通过对６０例不同麻醉下实施乳癌根治术病例的临床观察，比较其在术中呼吸循环等方面的变化，结果表明，硬膜外麻醉用于乳癌手术，对呼吸循环有一定的影响，易出现阻滞不全；而气管内插管复合静脉麻醉则具有呼吸，循环稳定的优点，亦易达到满意的麻醉效果。     

人脐静脉内皮细胞原代培养方法的建立

目的：探索并建立人脐静脉内皮细胞（删Ⅶc）体外稳定培养的方法。方法：以1％Ⅱ型胶原酶消化收集人脐静脉内皮细胞，用嘲加10％的胎牛血清进行培养，免疫细胞化学方法鉴定内皮细胞。结果：原代培养的内皮细胞镜下呈典型的铺路石或者鹅卵石样排列，3～4d时生长最快。5d左右融合；免疫细胞化学染色显示内皮细胞Ⅷ因子相关抗原表达阳性。结论：酶消化法获得的原代血管内皮细胞有较高的存活率，可以作为基础和临床研究的良好模型。     

Breakdown of lawsonite subsequent to peak UHP metamorphism in the Dabie terrane and its implication for fluid activity

Abundant occurrences of quartz vein within eclogites in the Dabie-Sulu orogen provide us an opportunity to study metamorphic fluid flow during subduction and exhumation of continental crust. It is, however, usually short of petrological constraints on pressure and temperature of vein formation. This study focuses on kyanite-quartz veins within Iow-T/high-P eclogite in the Dabie terrane that contain unique polycrystalline aggregates, interpreted as pseudomorphs after porphyroblasts of lawsonite. Coesite pseudomorphs were found for the first time in garnet from eclogite, resulting in a revised estimate of peak P-T conditions at 670℃ and 3.3 GPa for the eclogite. This indicates a stability field at graphite/diamond transition, thus upgrading the HP unit to a UHP unit. Neither foliation texture, undulose extinction of quartz nor coesite were observed in quartz veins,although the peak P-T conditions were estimated the same as that in host eclogite in light of thermodynamic calculation based on mineral assemblage in kyanite-quartz veins.Therefore, the formation of the kyanite-quartz veins as wellas the breakdown of lawsonlte into the kyanite-quartz-zoisite assemblage took place during exhumation subsequent to the peak UHP conditions. In this regard, the continental subduction not only brought the water of water-bearing mineral such as lawsonite into the deep mantle, but also released the water from the mineral during exhumation.     

纳米银在小鼠体内的组织分布

将分散在生理盐水中的纳米银以尾静脉注射的方式注入小鼠体内,采用电感耦合等离子质谱(ICP-MS)法检测其在小鼠体内的组织分布情况,并利用DAS药物动力学软件分析其在血液中的动力学参数.实验结果显示:纳米银经尾静脉注射进入小鼠体内后,血液中的w(Ag)在染毒1 h内呈快速下降趋势,其后的24 h内w(Ag)处于平稳状态;纳米银在体内的消除半衰期为22.8 h,分布容积为26.8 L/kg;进入体内的纳米银可随血液循环快速分布到全身各脏器,6 h后即可在小鼠的多个主要脏器中检测到银的存在,其中脾脏中的w(Ag)约为203μg/g;滞留在体内的银主要分布在肝脏和脾脏中.由此可见,纳米银具有较高的组织亲和力,肝脏和脾脏可能是纳米银的主要蓄积作用靶器官.     

Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane

A series of polylactic acid (PLA) based nanocomposite fibrous membranes,including neat PLA,PLA/hydroxyapatite (HA) and PLA/HA/graphene oxide (GO),were fabricated via electrospinning method.The morphology and composition were investigated by scanning electron microscopy (SEM),X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) respectively.The thermal stability was determined by thermogravimetric analysis (TGA).To estimate the cytocompatibility of asprepared PLA/HA/GO fibrous membrane,MC3T3-E1 cells were cultured,and the corresponding cell adhesion and differentiation capability were investigated by fluorescence microscopy,SEM and MTT test.The electrospun ternary PLA/HA/GO membrane exhibited three-dimensional fibrous structure with relatively rough surface morphology,which made itself ideal for cell attachment and proliferation in bone tissue regeneration.The fluorescence microscopy,SEM and MTT test confirmed that the PLA/HA/GO nanocomposite fibrous membrane created a proper environment for the seeding and proliferation of MC3T3-E1 cells.     

基于区域形状的静脉图像特征提取与匹配

为了准确地对人的身份进行识别,提出了一种基于区域形状的静脉图像特征提取与匹配算法.静脉图像经预处理后得到二值图像,该算法首先对二值图像进行细化处理,得到了静脉的骨架信息;然后,标注4连通区域并寻找到与连通区域相连接的端点与交叉点;再利用最小距离法将连通区域的边缘逼近成若干条线段,将线段角度作为特征;最后,利用改进的最长公共子序列算法,进行了局部区域匹配,并利用改进的豪斯多夫距离算法进行整幅图像的匹配.实验表明,该算法获得的图像特征具有较高的区分度,识别效果受采集静脉图像中信息缺失的影响较小,正确识别率可达到96%以上.     

广西大厂锌铜矿方解石稀土元素地球化学特征

方解石是广西大厂矿区常见的脉石矿物。测试了拉么矽卡岩型锌铜矿和铜坑矿床深部矽卡岩型锌铜矿方解石稀土含量,锌铜矿的稀土元素总含量普遍较低,稀土元素总量(ΣREE)=11.15×10~(-6)～16.17×10~(-6),具有明显的有铕正异常,铕异常(δEu)为1.46～2.80,且轻重稀土分馏明显,轻稀土元素(LREE)/重稀土元素(HREE)为2.63～6.84,配分模式为具有铕正异常的轻稀土富集右倾型模式,这样的配分模式与锡多金属矿方解石稀土元素配分模式相似,暗示两者之间可能为同源不同阶段产物;且研究表明成矿流体来源为龙箱盖岩体岩浆结晶期后分异出的岩浆热液,成矿环境为还原环境过渡向氧化环境。     

肝内门—腔静脉分流术的应用解剖

目的：为临床进行肝内门—腔静脉分流术提供解剖学基础。方法：在31例成人肝标本上观测肝静脉的汇合类型、开口纵径、横径,肝静脉与门静脉交叉处的长度、横径、两静脉间距离。结果：三条肝静脉注入下腔静脉分三种类型,肝右静脉与门静脉右干及右后上支交叉、肝中、左静脉与门静脉左干交叉。结论：肝内门—腔静脉分流术的首选部位是在肝右静脉与门静脉右干及右肩上支之间;其次是在肝中静脉与门静脉左干之间;肝左静脉不宜行肝内门—腔静脉分流术。     

多孔纤维吸声材料填充蜂窝结构的声学性能

本文理论研究了多孔纤维吸声材料填充矩形蜂窝结构的声学特性.假设周期蜂窝结构将多孔纤维吸声材料划分为独立周期子空间,理论建模中选取单个蜂窝胞元进行分析.蜂窝结构内部的多孔纤维吸声材料采用等效流体模型进行模拟,斜入射的声波在各个子空间呈驻波分布,由声场的声压和速度可积分得到通过蜂窝结构入射平面和透射平面的能量流,从而得到多孔纤维吸声材料填充蜂窝结构的吸声及传声损失性能.与单一多孔纤维材料声学性能的对比发现,多孔纤维吸声材料填充蜂窝结构的吸声性能得到了有效提高.基于理论模型,进一步分析了结构参数对多孔纤维吸声材料填充蜂窝结构吸声/传声损失性能的影响.     

基于信息熵的局部二值模式手指静脉识别

为进一步提升手指静脉识别算法的识别率与识别速度,在图像处理阶段,提取出手指图像的感兴趣区域(region of Interest, ROI),减少手指周围区域的干扰。为提升识别率,在局部二值模式 (local binary patterns, LBP)的基础上,引入像素邻域之间的关系,增强LBP的识别性能;然后将信息熵与改进型LBP结合得到新的ELBP特征,最后采用主成分分析(principal component analysis,PCA)降维,以减少识别时间,去除冗余特征。通过对比欧氏距离与曼哈顿距离构建的分类器,与其他主流特征比较,验证算法的识别性能。在SDUMLA数据库与天津市智能实验室采集指静脉图像数据库上,保证了算法的识别速度前提下,分别取得了99.53%、99.84%的识别率,与其他识别算法相比识别率有明显的提高。