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排序方式: 共有51条查询结果,搜索用时 189 毫秒
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22.
白藜芦醇诱导VEGF表达促进缺血再灌注小鼠新生血管形成 总被引:1,自引:0,他引:1
研究白藜芦醇能否诱导小鼠缺血,再灌注后缺血区域新生血管形成及其与血管内皮细胞生长因子(VEGF)表达的相关性,用90只雄性BALB/c小鼠随机分为单纯缺血组、白藜芦醇组及假手术组,采用大脑中动脉线栓法制作局灶性脑缺血模型,免疫组化法测定微血管密度,Western blot检测VEGF蛋白表达.结果白藜芦醇处理组与单纯缺血对照组微血管计数存在差异,并且有统计学意义(P<0. 05),白藜芦醇处理组在各时间点VEGF蛋白表达水平均较高(P<0.05).说明白藜芦醇可以诱导脑缺血后VEGF早期表达,促进缺血区域新生血管形成,发挥脑保护作用. 相似文献
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Y. Mabe R. Pérez K. Tatemoto J. P. Huidobro-Toro 《Cellular and molecular life sciences : CMLS》1987,43(9):1018-1020
Summary Intravenous injection of neuropeptide Y (NPY) caused short-lasting dose-dependent pressor responses in anesthetized rats. NPY was equipotent with noradrenaline in producing proportional pressor effects. Chemical sympathectomy, following the administration of 100 mg/kg 6-hydroxydopamine (6-OHDA), significantly potentiated the systemic pressor effects elicited by NPY or noradrenaline. Pretreatment with 2 nmol NPY enhanced the noradrenaline-induced pressor response in control rats. NPY did not change the basal tension of isolated rat aortic strips but significantly potentiated the contractile activity induced by 16 nM noradrenaline. This effect of NPY was not observed in aortic strips from rats pretreated with 6-OHDA. The presence of pre-and postsynaptic sites of action for NPY in the cardiovascular system of the rat is discussed. 相似文献
25.
Ramaswamy Bhuvaneswari Yik Yuen Gan Khee Chee Soo Malini Olivo 《Cellular and molecular life sciences : CMLS》2009,66(14):2275-2283
Photodynamic therapy (PDT), the activation of a photosensitive drug in tumor tissue with light of specific wavelength, has
been used effectively to treat certain solid tumors. Though therapeutic responses are encouraging, PDT-mediated oxidative
stress can act as an angiogenic switch that ultimately leads to neovascularization and tumor recurrence. This article explores
the effect of PDT on angiogenesis in different tumor models. Overexpression of proangiogenic vascular endothelial growth factor,
cyclooxygenase-2 and matrix metalloproteases has often been reported post-illumination. Recent clinical studies have demonstrated
that inhibiting angiogenesis after chemotherapy and radiotherapy is an attractive and valuable approach to cancer treatment.
In this review, we report the effective therapeutic strategy of combining angiogenesis inhibitors with PDT to control and
treat tumors. 相似文献
26.
上段排骨及其小头半关节作为自身替代病骨段和关节缺损,是唯一理想的选材。全文就移植代替的价值、术式、应用中的问题作了讨论。 相似文献
27.
张国祥 《齐齐哈尔大学学报(自然科学版)》1991,(2)
应力孤子波是一类由非线性作用引起的行波,它在运动过程中形状保持不变。本文在血管简化模型基础上,分析出血管径向的波动具有孤子波性质,这对分析血管脉象是有益的。 相似文献
28.
张义科 《河北大学学报(自然科学版)》1994,(4)
白洋淀重新蓄水后维管束植物区系组成已完全恢复,现记录有19科32属46种。金鱼藻科、花蔺科、茨藻科、菱科、浮萍科和睡莲科在本区系中占有重要地位。区系的地理成分以世界分布属居首(29.1%),其次是泛热带分布属(19.4%),北温带分布属居第三位(9.7%)。有4个生态类型:挺水植物(41.3%),浮叶植物(17.4%),漂浮植物(8.7%),沉水植物(32.6%)。 相似文献
29.
Hongyi Li Jiabin Tong Weiguo Cao Min Chen Hua Li Hong Dai Liang Xu Xiaoliang Chen 《科学通报(英文版)》2014,59(35):5090-5095
A subcutaneous transport pathway in humans has been previously visualised by injection of a paramag- netic tracer into the specific region of skin. In the current study, we further investigated the behaviours of imaging tracers in the transport pathways using imaging techniques. Three types of imaging tracers, including Gd-DTPA, iodised oil, and fluorescein sodium, were hypodermically injected into different acupuncture points of healthy volunteers to visualise the transport pathways by magnetic resonance imaging (MRI), X-ray, CT, and a digital fluorescein camera. Several longitudinal transport pathways in the arms and feet, which represent venous vessels and subcutaneous transport pathways (STPs) without well-defined boundaries, were visualised by MRI. Among the visualised veins, the partial walls of a few veins were enhanced by Gd-DTPA. The fluorescent images further indicated that STPs likely repre- sent boundless pathways. The findings in this study sug- gested that specific anatomical structures within the subcutaneous tissues or the partial walls of certain veins were not vascular conduits but rather represented unique transport pathways in humans that warrant extensive future studies. 相似文献
30.
杨树维管组织细胞生物学研究进展 总被引:1,自引:0,他引:1
杨树是林业生产中的速生用材料种之一,也是林木研究中重要的目的树种。长期以来对杨树的应用基础性研究已取得了长足的进展,初步形成了林木维管组织形成和结构的基础知识,提出在杨树的茎端存在初生一次维管组织过渡区,阐明了杨树次生维管组织的结构特征及其发育影响因子与细胞化学变化;分子水平上的研究初步为维管组织发育的分子同理与调控机制的阐明提供了可靠的佐证。笔从广义的细胞生物学角度,对民树维管系统的解剖学和生理学研究的进展进行了评述。 相似文献