信息技术在基因组和蛋白质组研究中的应用

本文综述了信息技术在生物学研究前沿领域,特别是基因组和蛋白质组研究方面的应用,重点展示生物信息技术在信息交流手段、基因克隆与定位、核酸和蛋白质序列分析、空间结构预测和蛋白质功能研究方面的具体运用方法,拓展了生物技术概念的内涵与外延。     

转变观念发展高职

本文针对中专升格的高职学院,运用系统的观点,探讨转变办学观念的载体,提出发展高职“五制”的技术内涵。     

潜空导弹运载器水下弹道仿真研究

在建立适合于运载器六自由度运动的数学模型的基础上,建立了光纤对运载器作用力的数学模型,然后对潜空导弹运载器的水下弹道进行了仿真研究.结果表明运载器运动稳定,控制规律合理.     

深圳港液化天然气船航行安全风险评估

对中国第一座海运LNG接收站LNG船航行安全进行了安全评估.采用美国海岸警卫队的《基于风险的决策指南(RBDM)》中的预先风险评估方法(PrRA),使用了事件树方法和风险指数方法.根据ALARP原理,评估出三种情景属于需改进的范围,针对评宿结果提出了五条减少风险水平的建议.     

Multi-objective carrier chaotic evolutionary algorithm for DNA sequences design

DNA computing is a new vista of computation, which is of biochemical type. Since each piece of information is encoded in biological sequences, their design is crucial for successful DNA computation. DNA sequence design is involved with a number of design criteria, which is difficult to be solved by the traditional optimization methods. In this paper, the multi-objective carrier chaotic evolution algorithm (MCCEA) is introduced to solve the DNA sequence design problem. By merging the chaotic search base on power function carrier, a set of good DNA sequences are generated. Furthermore, the simulation results show the efficiency of our method.     

Dialdehyde starch nanoparticles： Preparation and application in drub carrier

Dialdehyde starch nanoparticles (DASNP) were prepared by the redox reaction of NaIO4 and starch in water-in-oil microemulsion. IR spectrum showed that DASNP had aldehyde groups, and quantitative alkali consumption showed that its dialdehyde content was about (50±5)%. The average diameter of DASNP determined by SEM was about 100 nm. TGA-DTA showed that its thermal stability was better than starch nanoparticle (StNP) and dialdehyde starch (DAS). Its low biological toxicity was detected by cell experiment. Also the best mass ratio of doxorubicin (DOX) to combined DASNP detected by UV-VIS was 15 : 1, and the product was effective for controlled release of DOX. The cell experiment showed that the drug-carrier particle (DOX-DASNP) can release DOX for a long time and strengthened the effect of the anticancer drug. This work demonstrates that the DASNP, which has good thermal stability, small particle size, low biological toxicity, and slowly anticancer drug-releasing to strengthen drug effect, is a potentially useful carrier for anticancer drug.     

慢病毒载体研究进展

慢病毒作为一种特殊的逆转录病毒,与通常使用的逆转录病毒载体和腺病毒载体比较,具有可感染分裂细胞及非分裂细胞、转移基因片段容量较大、目的基因表达时间长、不易诱发宿主免疫反应等优点,已成为当前基因治疗和转基因动物中载体研究的热点。近年来对其基础生物学特性、载体改造及其应用等研究均取得了较大进展。本文就慢病毒载体及应用方面的研究进展作一综述。     

分形调制的硬件实现方案

以Mallat算法和多相滤波器为基础,提出了一种分形调制和解调系统的硬件实现方案,对成形和同步系统进行了综合设计。针对同步中对定时精度敏感,易假同步等弱点,在最大似然估计算法的基础上采取了载波相位恢复与码元帧同步相结合的方式,同时也可以对假同步进行检测和纠正。仿真和测试的结果表明,该方案在信噪比为10 dB的条件下,能使单个子带的误码率达到10-5数量级。     

住宅小区智能控制与管理系统

介绍了一种住宅小区智能控制与管理系统的网络结构及其实现，在此系统中，家庭自动化系统采用有线电缆与电力线载波通信相结合的机制；家庭自动化系统与大楼集中控制站之间的通信通过RS485实现；大楼集中控制站、公用设施控制站与小区中央控制站之间的通信通过LONWORKS局部操作网实现。     

有关改变教学方式的苦干问题析论

对从根本上改变现有的教学方式的必要性做了简要的说明；对长期以来导致教学方式几乎没有根本的改变的原因进行了分析论述；提出了新的教学方式构想以及为实现这一构想所应做的事情。