总星系局爆宇宙理论

大爆炸宇宙理论是一个非常成功的宇宙理论,它在经过古斯等人提出的暴涨理论修正后日趋完善。但即使这样也还存在几个难题无法解决：（1）欧洲普朗克望远镜揭示的宇宙背景辐射的不对称性;（2）宇宙中所有物质来源于大爆炸没有实验依据;（3）存在暴涨中宇宙膨胀的超光速问题。为了解释上述难题,本文提出了一种建立在大爆炸宇宙理论基础上的多宇宙模型：总星系局爆宇宙模型。该模型可以很好地解决上述难题,文中提出了检验理论模型新的实验方法,通过实验可以最终确认真实的宇宙到底更符合哪个模型。、     

时间的操作定义

关于时间是什么？牛顿在《自然哲学的数学原理》一书中对“绝对时间”给出了一个描述,爱因斯坦没有给“相对论时间”下过定义,所以到目前为止,还没有一个统一的时间定义。无论是牛顿的时间还是爱因斯坦的时间都需要用他们建立的整个理论体系去理解时间的含义,这样的结果导致普通人理解物理时间概念的困难．本文试图给时间下一个操作定义,以弥补关于时间概念在认识论上的不足。并用相关实验说明定义的正确性,最后用新的时间定义重新分析了相对论运动时钟变慢的物理原因。     

地方性本科院校加强质量工程建设的实践与思考——以新乡学院机械专业为例

作为新办地方性本科院校,和其他本科院校相比,新乡学院在办学经验、师资力量等方面还存在着一定的差距.只有认清自己的优势和劣势,不断探索新的办学路子,总结实践经验,并以质量工程建设为主要任务,学校的办学质量才能得到有效的提高.本文以新乡学院机械类专业的质量工程建设为例,在如何利用质量工程建设促进办学质量方面进行了积极的探索.     

基于单元特定事件的多缓冲炼钢连铸生产调度建模

针对炼钢-连铸生产实际,提出多缓冲炼钢-连铸生产调度问题。考虑缓冲、分配、排序、时间、连铸等实际约束,建立基于单元特定事件的连续时间混合整型线性规划模型,实际案例验证了该模型的有效性。     

激光清洗技术的初步研究和应用

激光清洗技术与其他清洗方法（化学清洗、超声波清洗等）相比,具有保证清洗对象无损、清洗效果好、精细、无污染等优点,正在被广泛的研究和应用.根据去除原理的不同,激光清洗技术被分类为干式激光清洗、湿式激光清洗和激光等离子体冲击波等方法.本文介绍了本单位项目组对激光清洗技术的初步研究和应用.     

Rong Shuan Jiao Nang in the treatment of acute mountain sickness and high altitude myocardial ischemic syndrome in Yushu

To evaluate the therapeutic effects of Rong Shuan Jiao Nang (RSJN) on treatment of acute mountain sickness (AMS) and high altitude myocardial ischemic syndrome in workers in Yushu,three groups were studied: group A (60 patients with AMS,given RSJN),group B (15 patients with altitude myocardial ischemic syndrome, given RSJN),and group C (control,without drugs). All studied subjects were lowland workers who were first time entry to Yushu for work at an altitude of 4 250 m. During the course of treatment,a routing physical examination was performed,AMS Lake Louise Scores were estimated,arterial oxygen saturation (SaO2),electrocardiography and hemoglobin concentration were measured before and after using RSJN for 10 days. In group A,the effective rate was 68 %,symptomatic improvement in 54 cases (90 %) within 5 days. In group B,the effective rate was 93 %,episodes of angina pectoris stopped in 12 patients within 3 ~ 7 days,one lasted 8 days. After treatment, the level of SaO2 increased 15.5 %,21.8 % and 5.6 % in group A,group B and group C,respectively. RSJN taken at the start of the arrival at Yushu can decrease AMS scores and facilitate cure. If taken after the illness has begun,RSJN may help lessen symptoms,especially effectively improved angina pectoris of the high altitude myocardial ischemic syndrome. Symptoms usually subside after 3 ~ 8 days. RSJN should be continually used for at least 7 days after ascent.     

Design, synthesis and nonlinear optical properties of “dendronized hyperbranched polymers”

A new type of dendritic polymer, named dendronized hyperbranched polymer (DHP), was prepared successfully by the macro-monomer approach. Thanks to the perfect 3D isolation effects, DHPG1 exhibited good NLO property with d 33 value of 133 pm/V, higher than its analogues of dendronized polymer and dendrimer, and its stability of NLO effect was also enhanced.     

Overexpression of N-cadherin is correlated with metastasis and worse survival in colorectal cancer patients

N-cadherin is related to the progression and metastases of several solid carcinomas. However, it was still unclear whether N-cadherin is overexpressed in colorectal malignant tumors that have stronger malignant tendency. In this study, we used immunohistochemistry to detect the expression patterns of N-cadherin in both the primary tumors and their normal mucosa tissues of 120 patients with colorectal cancer. We revealed that N-cadherin was expressed in 78.3% (94/120) of colorectal tumor tissues and in only 9.2% (11/120) of paired distant normal mucosa tissues with a significant difference (P=0.000). The low, moderate, and high expression of N-cadherin protein was 42.5%, 30.8%, and 26.7%, respectively. N-cadherin overexpression was associated with advanced TNM stage, lymph nodes metastasis and distant metastasis (P<0.05). Patients with N-cadherin overexpressed showed the obvious lower overall survival rate than those with moderate and low expression, and patients with low expression had a better survival rate than those with moderate and high expression (P<0.05). In conclusion, high N-cadherin expression may lead to tumor aggressiveness and metastatic potential in colorectal cancer, and may prove to be a possible prognostic factor.     

Informative gene selection using the Algebraic Connectivity Strength of Point and Scoring Criteria

This paper presents a novel method that integrates the Algebraic Connectivity Strength of Point(ACSP) and Scoring Criteria to identify genes associated with tumor type.First,for each gene,the ACSP is used to identify reliable expression levels of the gene in all the samples.The informative genes are then selected using Scoring Criteria based on these reliable expression levels.Finally,the Support Vector Machine(SVM) classifier is used to classify the two datasets of gene expression profiling.The results show that the informative genes selected by the proposed method have higher credibility than those selected by Scoring Criteria alone.     

城市社区图书馆LivingLibrary基于湿营销策略活动策划——基于湿营销策略

LivingLibrary是新型的图书馆服务形式,在图书馆阅读推广、文化输出过程中具有传统阅读服务不可比拟的优势。阐述了LivingLibrary的起源及其在我国的发展,分析了社区图书馆开展LivingLibrary活动的优势,提出了LivingLibrary活动的湿营销方案。