仁科芳雄对日本物理学的贡献

仁科芳雄被尊称为＂日本现代物理学之父＂,在东京帝国大学电气工程学毕业后最终转向物理学.欧洲留学八年后,把先进的量子力学引进日本,并对宇宙射线,X-射线和核物理深有研究,著名物理学家汤川秀树和朝永振一郎也是在仁科的帮助下获得诺贝尔物理学奖,对日本的物理研究环境、教育事业、以及战后经济复兴也做出了巨大的贡献.     

促进知识产权商用化 助力产业转型升级

以台湾为例,对知识产权商用化经验进行分析,研究知识产权商用化对经济及产业转型升级的助推作用,为广东省政府部门积极推进知识产权商用化,促进广东产业转型升级提供参考建议。     

路桥施工过程粉尘污染对人肺部健康的影响研究

以典型的路桥施工过程大气监测样品中主要污染物Pb为基准,用粒径为100nm纳米Pbo2模拟其在大气粉尘颗粒中的存在形态,采用人肺部细胞A549为模型,测试其对肺细胞的毒性,从而考察路桥施工过程粉尘对人肺部健康的影响.结果表明,纳米铅对A549细胞呈现依赖毒性,细胞存活率明显减少,细胞有明显的形态学异常变化,并且无毒水平上0.25μg/L的纳米铅使得A549细胞中氧化自由基ROS增加了200%,超氧化物歧化酶SOD表达量下降,提示细胞受到氧化损伤而可能导致细胞功能弱化.     

Neuropsychological impairment: the disturbed effect of self-processing in patients with major depressive disorder

Neuropsychological impairment has long been established as a fundamental characteristic of depression, but a generally accepted, specific pattern of neuropsycho- logical impairment has not been summarized. In this study, we examined the classic neuropsychological paradigm of self-face recognition, to explore whether the self was impaired in major depressive disorder （MDD）. Eighteen MDD patients and 20 healthy subjects were recruited to participate in this study. By using a face morphing tech- nique, we measured the size of processing bias in MDD patients during different face discrimination tasks relative to controls. Results of analysis of variance （ANOVA） showed a significant main effect of Group （F（1, 36） = 7.388, P = 0.01）. Subsequent independent t-tests further revealed that self bias （t = 2.636, P = 0.012） and self-recognition bias（t = 2.190, P = 0.035） observed in self-famous task and self-stranger task respectively for patients were significantly greater than that for controls. Both self-processing and self- recognition were impaired in patients with MDD, indicating that MDD individuals might exist level of self-abnormali- ties. These findings provide a new perspective for further study on the etiological and pathological mechanisms of MDD.     

河北省高校内部控制现状研究

近年来由于高校内部控制的不完善,导致"腐败门"事件频频发生,这已引起社会广泛关注。为了解河北省高等院校内部控制的现状,课题组依据2014年1月1日开始执行的《行政事业单位内部控制规范》的内容,从风险评估现状、单位层面内部控制、业务层面内部控制三个方面设计了问卷,并对问卷结果加以汇总,发现目前高等院校的内部控制程序执行不够彻底,属于基本落实。只有完善相应的内控机制并增强执行力度,才能保证高校活动的健康开展。     

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population

Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD (P = 5.00 × 10?3, stage 2 validation; P = 3.00 × 10?3, P = 1.19 × 10?? and P = 4.00 × 10?3 in three independent stage 3 replication populations; P = 4.87 × 10?12, odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.     

Regulatory circuits controlling vascular cell calcification

Vascular calcification is a common feature of chronic kidney disease, cardiovascular disease, and aging. Such abnormal calcium deposition occurs in medial and/or intimal layers of blood vessels as well as in cardiac valves. Once considered a passive and inconsequential finding, the presence of calcium deposits in the vasculature is widely accepted as a predictor of increased morbidity and mortality. Recognition of the importance of vascular calcification in health is driving research into mechanisms that govern its development, progression, and regression. Diverse, but highly interconnected factors, have been implicated, including disturbances in lipid metabolism, oxidative stress, inflammatory cytokines, and mineral and hormonal balances, which can lead to formation of osteoblast-like cells in the artery wall. A tight balance of procalcific and anticalcific regulators dictates the extent of disease. In this review, we focus on the main regulatory circuits modulating vascular cell calcification.     

旋转的Rayleigh-Bénard问题的Lorenz模型及数值模拟

利用截谱方法,将旋转的Rayleigh-Bénard问题转化为四维的Lorenz模型,估计出此Lorenz模型的参数取值范围为τ∈[0,2],r∈(0,∞),b∈[0,8/3]。比较了四维Lorenz方程与经典的三维的Lorenz方程(无旋转)的不同之处,在此基础上进行了数值模拟,结果表明旋转可以增加系统稳定性。     

图簇h(PmSG（r,n+1）)的伴随多项式的因式分解及其补图的色等价性

本文利用图的伴随多项式的性质及其伴随分解的图论方法,讨论了h(PSmG(r,n+1))型图的伴随多项式的因式分解,证明了在不同条件下这类图的补图的色等价性。