河北省高校内部控制现状研究

近年来由于高校内部控制的不完善,导致"腐败门"事件频频发生,这已引起社会广泛关注。为了解河北省高等院校内部控制的现状,课题组依据2014年1月1日开始执行的《行政事业单位内部控制规范》的内容,从风险评估现状、单位层面内部控制、业务层面内部控制三个方面设计了问卷,并对问卷结果加以汇总,发现目前高等院校的内部控制程序执行不够彻底,属于基本落实。只有完善相应的内控机制并增强执行力度,才能保证高校活动的健康开展。     

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population

Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD (P = 5.00 × 10?3, stage 2 validation; P = 3.00 × 10?3, P = 1.19 × 10?? and P = 4.00 × 10?3 in three independent stage 3 replication populations; P = 4.87 × 10?12, odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.     

Regulatory circuits controlling vascular cell calcification

Vascular calcification is a common feature of chronic kidney disease, cardiovascular disease, and aging. Such abnormal calcium deposition occurs in medial and/or intimal layers of blood vessels as well as in cardiac valves. Once considered a passive and inconsequential finding, the presence of calcium deposits in the vasculature is widely accepted as a predictor of increased morbidity and mortality. Recognition of the importance of vascular calcification in health is driving research into mechanisms that govern its development, progression, and regression. Diverse, but highly interconnected factors, have been implicated, including disturbances in lipid metabolism, oxidative stress, inflammatory cytokines, and mineral and hormonal balances, which can lead to formation of osteoblast-like cells in the artery wall. A tight balance of procalcific and anticalcific regulators dictates the extent of disease. In this review, we focus on the main regulatory circuits modulating vascular cell calcification.     

旋转的Rayleigh-Bénard问题的Lorenz模型及数值模拟

利用截谱方法,将旋转的Rayleigh-Bénard问题转化为四维的Lorenz模型,估计出此Lorenz模型的参数取值范围为τ∈[0,2],r∈(0,∞),b∈[0,8/3]。比较了四维Lorenz方程与经典的三维的Lorenz方程(无旋转)的不同之处,在此基础上进行了数值模拟,结果表明旋转可以增加系统稳定性。     

图簇h(PmSG（r,n+1）)的伴随多项式的因式分解及其补图的色等价性

本文利用图的伴随多项式的性质及其伴随分解的图论方法,讨论了h(PSmG(r,n+1))型图的伴随多项式的因式分解,证明了在不同条件下这类图的补图的色等价性。     

吕梁山隧道3#斜井及正洞通风技术总结

针对吕梁山隧道3#斜井及正洞的特点,采取分阶段通风的方法,取得良好的通风效果,以保证工程的顺利进行。     

物联网在工业中的应用

工业是物联网应用的重要领域,物联网在工业领域的应用主要体现在制造业供应链管理、生产过程工艺优化、产品设备监控管理、环保监测及能源管理、安全生产管理和与先进制造技术相结合。     

茂钠制备新方法

以氢氧化钠（代替金属）和环戊二烯为原料制备了茂钠。着重研究了反应物配比，温度及固体ＮａＯＨ的颗粒粒径对反应速度和产物收率的影响规律，结果表明，当ＮａＯＨ／ＣＰＤ的摩尔比为４／１，粒径在１￣２ｎｍ，温度为０℃时，产物收率可高达９５％￣９７％。