Protective effect of sodium butyrate on the cell culture model of Huntington disease

This study aimed to develop a cell culture model of Huntington disease and observe the effect of sodium butyrate on this cell culture model. Exon 1 of both a wild type and a mutant IT15 gene from the genomic DNA of a healthy adult and a patient with Huntington disease was amplified and cloned into the eukaryotic expression vector pEGFP-C1. Human neuroblastoma SH-SY5Y cells were transiently transfected with these recombinant plasmids in the absence and presence of sodium butyrate (0.1, 0.2, 0.5, 1.0 mmol/L). The MTT assay was used to measure cell viability. The results indicated that the N-terminal fragment of mutant huntingtin formed perinuclear and intranuclear aggregates and caused a decrease of SH-SY5Y cell viability. Sodium butyrate inhibited the decrease of SH-SY5Y cell viability caused by the N-terminal fragment of mutant huntingtin. This suggests that sodium butyrate has a protective effect on this cell culture model of Huntington disease.     

Cloning and expression of putative ethylene receptor genes in soybean plant

Ethylene plays important roles in plant growth, development, and stress responses, and ethylene receptors have been identified and studied extensively in various plant species. Here we report the cloning of four ethylene receptor genes from soybean, i.e. GmETR1, GmERS1, GmETR2 and GmEIN4. Construction of the phylogenic tree showed that GmETR1 and GmERS1 belong to subfamily I whereas GmETR2 and GmEIN4 belong to subfamily II. The four ethylene receptor genes showed different tissue-specific expression patterns in roots, stems, leaves, cotyledons, flowers, pods and seeds of soybean. These genes were differentially regulated by various abiotic stresses and plant hormones. The possible roles of the four genes in soybean plant were also discussed.     

回归系数的一种有偏估计

在线性回归模型Y=Xβ＋ε；E（ε）=0；Cov（ε）=σ^2V，V〉0下，给出了一种新的有偏估计β^-（F（K））=（X′V^-1X＋TF（K）T′）^-1X′V^-1Y，讨论了这种有偏估计的优良性，推广了已有的相关结果．     

基于小波变换和可操纵金字塔算法的图像纹理分析

本文首先介绍了图像小波变换和可操纵金字塔在图像处理问题中的广泛应用及其数学原理和特点,对二者进行比较,然后分别利用小波变换和可操纵金字塔滤波器进行图像纹理分析,最后给出了结果,并进行分析。     

传统产业高新技术化的动力机制

从企业的利润最大化目标出发,论述了市场需求拉力、市场竞争压力、技术创新与技术中介的推动力以及政府行为支撑力在企业的技术创新与企业的技术改造中的作用;各动力间相互关联、相互促进的机理及其反馈、放大效应;构建了传统产业高新技术化的动力机制模型。     

Control of group velocity in an annular chain of microring coupled-resonator optical waveguides

In order to control group velocity,an annular chain of microring coupled-resonator optical waveguides was analyzed,and its transmission spectra were obtained using the transfer matrix method. The result showed that the curvature of the chain caused the dispersion curves to shift and the resonance fre-quency got fixed. It is therefore concluded that the group velocity of light in the annular chain of mi-croring coupled-resonator optical waveguides can be controlled by adjusting the curvature of the chain. We believe that such an annular chain can be used as an optical buffer or signal retarder for optical communication.     

基于OrCAD／PSPICE的二阶系统阶跃响应仿真实验

传统实物实验由于受实验条件的限制，实验项目往往开设数量有限，实验内容更新缓慢，不利于学生设计能力和创新能力的培养。仿真实验是以软件为实验平台，具有扩展性，与实物实验相比，既能节省投资，又能根据课程内容需要随时增加实验内容，提高实验教学效果。文章简要介绍了OrCAD／PSPICE实现电子电路仿真的步骤，并详细阐述了利用OrCAD／PSPICE对二阶系统阶跃响应进行仿真分析的方法，为电子电路仿真实验的设计和开发提供了新的平台。     

基于粒子群算法的短期电力负荷预测

根据电力负荷的主要影响因素,考虑了休息日和气候因素的影响,建立了基于粒子群算法(PSO)的级联网络短期负荷预测模型.通过粒子群算法对级联网络的训练进行优化,提高模型的运算速度.结果表明,该方法预测精度较高,效果较好.     

基于系统动力学的防空装备体系优化模型

运用大系统理论研究防空装备体系的优化问题。基于系统动力学理论,通过对系统状态描述、结构分析设计和定量关系控制,建立体系优化模型,评估防空装备体系的系统效能。仿真结果表明此方法和所建模型是合理有效的,对装备体系优化具有适用性。     

以聚二烯丙基二甲基氯化铵为探针测定人血清中总蛋白的含量

通过共振光散射(RLS)技术, 将聚二烯丙基二甲基氯化铵(PDDA)作为探针应用于人血清中总蛋白含量的测定. 在一定的人血清白蛋白(HSA)浓度范围(2.35×10^-8-~1.17×10^-6mol/L)内, HSA PDDA体系的RLS强度随HSA浓度的增加而增加, 并具有一定的线性关系. 将该方法应用于实际人血清中总蛋白含量的测定, 其结果与考马士亮蓝法得到的结果进行对比, 较为满意.