全文获取类型
收费全文 | 86篇 |
免费 | 0篇 |
专业分类
系统科学 | 1篇 |
现状及发展 | 14篇 |
研究方法 | 13篇 |
综合类 | 54篇 |
自然研究 | 4篇 |
出版年
2016年 | 1篇 |
2012年 | 2篇 |
2011年 | 10篇 |
2010年 | 2篇 |
2008年 | 2篇 |
2007年 | 6篇 |
2006年 | 5篇 |
2005年 | 3篇 |
2004年 | 6篇 |
2003年 | 4篇 |
2002年 | 4篇 |
2001年 | 4篇 |
2000年 | 5篇 |
1999年 | 6篇 |
1998年 | 1篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1991年 | 1篇 |
1990年 | 3篇 |
1988年 | 3篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1966年 | 2篇 |
1960年 | 1篇 |
排序方式: 共有86条查询结果,搜索用时 171 毫秒
31.
32.
33.
34.
Lu LF Lind EF Gondek DC Bennett KA Gleeson MW Pino-Lagos K Scott ZA Coyle AJ Reed JL Van Snick J Strom TB Zheng XX Noelle RJ 《Nature》2006,442(7106):997-1002
Contrary to the proinflammatory role of mast cells in allergic disorders, the results obtained in this study establish that mast cells are essential in CD4+CD25+Foxp3+ regulatory T (T(Reg))-cell-dependent peripheral tolerance. Here we confirm that tolerant allografts, which are sustained owing to the immunosuppressive effects of T(Reg) cells, acquire a unique genetic signature dominated by the expression of mast-cell-gene products. We also show that mast cells are crucial for allograft tolerance, through the inability to induce tolerance in mast-cell-deficient mice. High levels of interleukin (IL)-9--a mast cell growth and activation factor--are produced by activated T(Reg) cells, and IL-9 production seems important in mast cell recruitment to, and activation in, tolerant tissue. Our data indicate that IL-9 represents the functional link through which activated T(Reg) cells recruit and activate mast cells to mediate regional immune suppression, because neutralization of IL-9 greatly accelerates allograft rejection in tolerant mice. Finally, immunohistochemical analysis clearly demonstrates the existence of this novel T(Reg)-IL-9-mast cell relationship within tolerant allografts. 相似文献
35.
Understanding changes in ontogenetic development is central to the study of human evolution. With the exception of Neanderthals, the growth patterns of fossil hominins have not been studied comprehensively because the fossil record currently lacks specimens that document both cranial and postcranial development at young ontogenetic stages. Here we describe a well-preserved 3.3-million-year-old juvenile partial skeleton of Australopithecus afarensis discovered in the Dikika research area of Ethiopia. The skull of the approximately three-year-old presumed female shows that most features diagnostic of the species are evident even at this early stage of development. The find includes many previously unknown skeletal elements from the Pliocene hominin record, including a hyoid bone that has a typical African ape morphology. The foot and other evidence from the lower limb provide clear evidence for bipedal locomotion, but the gorilla-like scapula and long and curved manual phalanges raise new questions about the importance of arboreal behaviour in the A. afarensis locomotor repertoire. 相似文献
36.
Strässer K Masuda S Mason P Pfannstiel J Oppizzi M Rodriguez-Navarro S Rondón AG Aguilera A Struhl K Reed R Hurt E 《Nature》2002,417(6886):304-308
37.
Duffy D Montgomery G Treloar S Birley A Kirk K Boomsma D Beem L de Geus E Slagboom E Knighton J Reed P Martin N 《Nature genetics》2001,28(4):315
Busjahn et al reported finding linkage between PPARG (3p25) and being a dizygotic (DZ) twin. We differentiate, as do the authors, between the conception of DZ twins, and being the viable result of such a conception. 相似文献
38.
39.
Structure and function of the sarcolemma of skeletal muscle 总被引:1,自引:0,他引:1
40.
Résumé Les auteurs ont trouvé quelques corrélations entre la formation des ions les plus abondants et la disposition des liaisons-éthyléniques dans les ions moléculaires de quelques terpènes. 相似文献