高等数学课程设置的多样化研究

由于专业和学生之间存在差异,在高等数学课程设置上必须实行多样化。具体说来,把高等数学的学习内容分为三个模块:基础模块、拓展模块(基地班)和应用模块,实践表明,这种多样化的高等数学课程设置取得了较好的教学效果。     

具有较小最大度的临界图边数的下界

运用Discharge法给出了不含2点和3点的6临界图及不含4点和5点的7临界图边数的下界．     

一种大管径煤气管道带压堵漏的应用

文章介绍了针对DN2200煤气总管泄漏,一种新型大管径煤气管道带压堵漏的性能和工作原理.     

国内高校人才培养模式发展趋势研究

从人才培养模式的定义出发,介绍了国内高校传统人才培养模式,总结了我国高校人才培养模式的发展趋势,认为不同的学校要根据自身的实际情况,结合社会需求构建科学的人才培养模式,形成自身的办学特色。     

省级实验示范中心在高校人才培养中的作用

对高校而言,实验教学是理论教学以及科研的基石,是深化理论知识,将间接经验与直接经验相结合的桥梁。论文结合安徽医科大学基础医学院病原与免疫学实验室的成长历程,阐述了省级实验示范中心在高校人才培养中的积极作用,体现在省级实验示范中心建设的引领下,实验中心本着提高实验教学水平和人才培养质量为目标,逐步实现提高实验室建设和管理水平,充分发挥实验示范中心的示范引领作用,以期全面提高高校的实验教学水平,并为高校进一步的实验教学改革创造条件。     

成年男性血小板正常参考值与地理环境的关系

为了给制定中国成年男性血小板正常参考值的统一标准提供科学依据,收集了中国100个单位测定的12670例成年男性血小板正常参考值,应用SPSS统计软件,运用相关分析和回归分析的方法,研究了其与7项地理因素指标的关系。     

Study of two-section composite chain of beads under vertical vibration

We investigated the dynamic properties of a two-section composite chain of beads under vertical vibration.By analyzing the chain’s motion,including phase-shift,mean dilation,center-of-mass displacement,and energy,we found that with different bead arrangements,the chain behaved in different ways.We believe that interaction existing at the interface between bead sections provides the underlying cause.This interaction causes different energy in different arrangements,which leads to different dynamic characteristics.     

基于动态语义服务描述的服务匹配的研究

本文将动态描述逻辑与语义服务描述语言相结合，提出了一种动态语义描述方法来描述Web服务，并在经典服务匹配基础上进行改进，完善了服务匹配的类型，提高了Web服务的查全率与查准率。     

Henon-Heiles体系的混沌控制

分析了不可积哈密顿系统混沌控制的LDG方法,并利用它实现了对Henon-Heiles体系周期1轨迹的混沌控制,通过实例分析了该方法的优点和局限性.     

Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid

We have reported that chymotrypsin B (CtrB) is not just a digestive enzyme but is also stored in lysosomes. Herein, we demonstrated a broad distribution of CtrB and explored the involvement of CtrB in apoptosis. Exposure of RH-35 cells to H₂O₂ or palmitate induced the redistribution of lysosomal CtrB into the cytoplasm as a result of lysosomal membrane permeabilization (LMP). Suppression of CtrB significantly blocked apoptosis, while overexpression of CtrB sensitized apoptosis markedly. CtrB could cleave Bid under neutral conditions. In RH-35 cells with Bid silenced, apoptosis induced by CtrB protein was attenuated, suggesting that CtrB mediates apoptosis of RH-35 cells mainly through processing Bid. Our data also suggest that LMP occurs earlier than mitochondrial outer membrane permeabilization; Bid activation initiated by caspase-8 might be reinforced by CtrB in consequence of LMP, which causes a positive feedback loop leading to the accumulation of tBid, and results in lysosome- and mitochondrion-dependent apoptosis.