非正交码移键控和码索引调制算法

针对正交码移键控(code shift keying, CSK)误比特率(bit error rate, BER)性能下降和非正交码索引调制(non-orthogonal-code index modulation, N-CIM)未能充分利用扩频码自相关性的不足,提出一种非正交CSK和码索引调制(non-orthogonal-CSK-code index modulation, N-CSK-CIM)算法。发送端信息比特分为调制比特和扩频码映射比特;调制比特用来进行符号调制,映射比特映射为扩频码的索引和码相位索引。首先根据调制比特进行符号调制,然后利用映射比特映射的扩频码索引选择同一原始扩频码,并根据码相位索引进行码移键控产生新的扩频码,调制后的符号实部与虚部分别用这一新的扩频码进行扩频。仿真结果表明,在加性高斯白噪声(additive white Gaussian noise, AWGN)信道和瑞利衰落信道中,相同信噪比时, N-CSK-CIM算法的BER性能优于N-CIM算法和正交CSK算法。     

ABg型树枝状高分子生长物理缺陷的理论研究

根据超支化高分子生长的空间位阻效应,通过利用简单的统计模型分析了ABg型反应体系在临界生长代数时形成缺陷结构的物理过程,进一步给出了临界反应代数与官能团之间的关系,扼要地讨论了超支化高分子的折光指数随生长代数的变化情况.     

钢筋砼结构施工期质量事故的可靠性诱因研究

施工期钢筋混凝土结构质量事故在其全寿命过程结构质量事故中所占比例高达2／3以上,对此进行了分析,认为对施工期钢筋混凝土结构的可靠性缺乏研究,是引起该阶段工程事故高发的主要原因之一。因此,提出了应用工程结构可靠性理论进行施工期钢筋混凝土结构质量控制研究的思路,其要点是通过对施工期钢筋混凝土结构质量事故发生诱因的剖析,建议在可接受的概率水平上,杜绝施工期质量事故的发生。     

木质素增强硬质聚氨酯泡沫塑料抗压性能研究

木质素纤维的添加量和粒度对增强硬质聚氨酯泡沫塑料抗压强度有一定的影响．实验结果表明：当木质素纤维的添加质量百分数为1．0％时,抗压强度达到最大值;当添加量一定时,平均粒度为10μm的木质素纤维增强效果较好．     

Many mechanisms, one entrance: membrane protein translocation into the nucleus

The inner nuclear membrane harbors a unique set of membrane proteins, many of which interact with nuclear intermediate filaments and chromatin components and thus play an important role in nuclear organization and gene expression regulation. These membrane proteins have to be constantly transported into the nucleus from their sites of synthesis in the ER to match the growth of the nuclear membrane during interphase. Many mechanisms have evolved to enable translocation of these proteins to the nucleus. The full range of mechanisms goes from rare autophagy events to regulated translocation using the nuclear pore complexes. Though mechanisms involving nuclear pores are predominant, within this group an enormous mechanistic range is observed from free diffusion through the peripheral channels to many distinct mechanisms involving different nucleoporins and other components of the soluble protein transport machinery in the central channels. This review aims to provide a comprehensive insight into this mechanistic diversity.     

How to halve ploidy: lessons from budding yeast meiosis

Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells. Meiotic cells halve their ploidy by undergoing two rounds of nuclear division (meiosis I and II) after a single round of DNA replication. Research in Saccharomyces cerevisiae (budding yeast) has shown that four major deviations from the mitotic cell cycle during meiosis are essential for halving ploidy. The deviations are (1) formation of a link between homologous chromosomes by crossover, (2) monopolar attachment of sister kinetochores during meiosis I, (3) protection of centromeric cohesion during meiosis I, and (4) suppression of DNA replication following exit from meiosis I. In this review we present the current understanding of the above four processes in budding yeast and examine the possible conservation of molecular mechanisms from yeast to humans.     

基于IMM的高动态GPS接收机载波跟踪算法

利用交互式多模型的带宽自适应调整特性实现了高动态与静态环境下通用的GPS信号载波跟踪算法。仿真结果表明,该算法在保证满足高动态GPS信号载波跟踪要求的前提下,降低了静态时的频率跟踪误差,避免了不同动态环境下多个载波跟踪算法及切换方案的设计。     

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313 high-risk adenoma) and 965 controls. In phase 2, we genotyped 42,708 selected SNPs in 2,873 CRC cases and 2,871 controls. In phase 3, we evaluated 11 SNPs showing association at P < 10(-4) in a joint analysis of phases 1 and 2 in 4,287 CRC cases and 3,743 controls. Two SNPs were taken forward to phase 4 genotyping (10,731 CRC cases and 10,961 controls from eight centers). In addition to the previously reported 8q24, 15q13 and 18q21 CRC risk loci, we identified two previously unreported associations: rs10795668, located at 10p14 (P = 2.5 x 10(-13) overall; P = 6.9 x 10(-12) replication), and rs16892766, at 8q23.3 (P = 3.3 x 10(-18) overall; P = 9.6 x 10(-17) replication), which tags a plausible causative gene, EIF3H. These data provide further evidence for the 'common-disease common-variant' model of CRC predisposition.     

明清民国时期潼关交通形式变迁的初步探究

潼关地处晋豫陕三省门户,地理位置险要,交通地位突出,历来在客运货运中所发挥的作用都不容小觑。潼关驿的设置在明清时期的通信、递运过程中占据着重要的位置,民国初年西潼公路的开通也彰显了潼关交通要道的地位,陇海铁路延展至潼关则开启了西北地区铁路运输的新形式。对这一选题的研究从一个侧面揭示了城镇发展与交通不可割裂的联系,潼关城交通形式近代化的变革给它的发展不断注入新的活力,带来新的契机,但同时也应看到交通的便捷并不是城镇繁荣的决定因素。     

NGO援建我国基层图书馆的核心理念及其启示

目前有众多国内外NGO(非政府组织)带着各自的核心理念对我国基层图书馆进行援建。罗列了其中有代表性的理念,对其核心组成部分及各自实现的方式进行了分析,从中得到了一些对于我国基层图书馆发展的启示。