首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   26297篇
  免费   878篇
  国内免费   1254篇
系统科学   1219篇
丛书文集   666篇
教育与普及   418篇
理论与方法论   136篇
现状及发展   1117篇
研究方法   84篇
综合类   24776篇
自然研究   13篇
  2024年   82篇
  2023年   286篇
  2022年   461篇
  2021年   448篇
  2020年   399篇
  2019年   208篇
  2018年   266篇
  2017年   295篇
  2016年   367篇
  2015年   752篇
  2014年   1014篇
  2013年   979篇
  2012年   1266篇
  2011年   1396篇
  2010年   1158篇
  2009年   1333篇
  2008年   1458篇
  2007年   1556篇
  2006年   1176篇
  2005年   1293篇
  2004年   1285篇
  2003年   1066篇
  2002年   874篇
  2001年   787篇
  2000年   833篇
  1999年   961篇
  1998年   673篇
  1997年   738篇
  1996年   636篇
  1995年   540篇
  1994年   504篇
  1993年   413篇
  1992年   445篇
  1991年   390篇
  1990年   338篇
  1989年   294篇
  1988年   272篇
  1987年   155篇
  1986年   109篇
  1985年   71篇
  1979年   61篇
  1974年   56篇
  1973年   49篇
  1972年   50篇
  1971年   66篇
  1970年   54篇
  1969年   68篇
  1968年   59篇
  1966年   55篇
  1965年   41篇
排序方式: 共有10000条查询结果,搜索用时 859 毫秒
981.
A complete solution classification of the perspective-three-point (P3P) problem is given by using the Gröbner basis method. The structure of the solution space of the polynomial system deduced by the P3P problem can be obtained by computing a comprehensive Gröbner system. Combining with properties of the generalized discriminant sequences, the authors give the explicit conditions to determine the number of distinct real positive solutions of the P3P problem. Several examples are provided to illustrate the effectiveness of the proposed conditions.  相似文献   
982.
研究了Littlewood-Paley积分算子(包括Lusin面积积分函数,Littlewood-Paley g函数和g*λ函数)及其与BM O函数生成的高阶交换子在具有两个变指数p(·),α(·)的Herz空间上的有界性,这里p(·),α(·)均满足一定的连续性条件。  相似文献   
983.
An Fe-based amorphous alloy was found to significantly enhance the reductive degradation of an azo dye in aqueous solution. The surface-area normalized rate constant was up to 2.0 L m-2 min-1 at room temperature,an order of magnitude larger than any previously reported value. The activation energy of the degradation process was calculated according to the Arrhenius equation,and a much lower value than those previously reported was obtained. Valence band measurement indicated that a depressed valence band maximum and a widened empty band were established in the amorphous ribbon. The unique structure of the amorphous alloy is important-it may reduce the activation energy of the degradation process and enhance the activity of the electrons,thus accelerating the degradation process.  相似文献   
984.
The metabolic syndrome is a cluster of common pathologies: abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension. At the molecular level, metabolic syndrome is accompanied not only by dysregulation in the expression of adipokines (cytokines and chemokines), but also by alterations in levels of leptin, a peptide hormone released by white adipose tissue. These changes modulate immune response and inflammation that lead to alterations in the hypothalamic ‘bodyweight/appetite/satiety set point,’ resulting in the initiation and development of metabolic syndrome. Metabolic syndrome is a risk factor for neurological disorders such as stroke, depression and Alzheimer’s disease. The molecular mechanism underlying the mirror relationship between metabolic syndrome and neurological disorders is not fully understood. However, it is becoming increasingly evident that all cellular and biochemical alterations observed in metabolic syndrome like impairment of endothelial cell function, abnormality in essential fatty acid metabolism and alterations in lipid mediators along with abnormal insulin/leptin signaling may represent a pathological bridge between metabolic syndrome and neurological disorders such as stroke, Alzheimer’s disease and depression. The purpose of this review is not only to describe the involvement of brain in the pathogenesis of metabolic syndrome, but also to link the pathogenesis of metabolic syndrome with neurochemical changes in stroke, Alzheimer’s disease and depression to a wider audience of neuroscientists with the hope that this discussion will initiate more studies on the relationship between metabolic syndrome and neurological disorders.  相似文献   
985.
基于流程仿真技术设计了管输工艺评价仿真系统的设计,包括仿真系统的功能与组成、实验方案编译器的设计、仿真控制器的设计、以及采用甘特图方法实现对实验方案的时序调整。该系统可实现管输工艺评价实验方案的流程仿真,为验证及优选管输工艺评价实验方案提供了技术平台。  相似文献   
986.
Functional telomeres are protected from non-homologous end-joining (NHEJ) and homologous recombination (HR) DNA repair pathways. Replication is a critical period for telomeres because of the requirement for reconstitution of functional protected telomere conformations, a process that involves DNA repair proteins. Using knockdown of DNA-PKcs and Rad51 expression in three different cell lines, we demonstrate the respective involvement of NHEJ and HR in the formation of telomere aberrations induced by the G-quadruplex ligand 360A during or after replication. HR contributed to specific chromatid-type aberrations (telomere losses and doublets) affecting the lagging strand telomeres, whereas DNA-PKcs-dependent NHEJ was responsible for sister telomere fusions as a direct consequence of G-quadruplex formation and/or stabilization induced by 360A on parental telomere G strands. NHEJ and HR activation at telomeres altered mitotic progression in treated cells. In particular, NHEJ-mediated sister telomere fusions were associated with altered metaphase-anaphase transition and anaphase bridges and resulted in cell death during mitosis or early G1. Collectively, these data elucidate specific molecular and cellular mechanisms triggered by telomere targeting by the G-quadruplex ligand 360A, leading to cancer cell death.  相似文献   
987.
文章结合运行调整,分析了300 MW直接空冷机组,锅炉采用中储式制粉系统运行中因给粉机叶轮孔板销子脱落,煤粉自流引起煤粉管道堵塞对机组安全运行的影响,通过对故障现象的分析,介绍了故障诊断及处理过程.  相似文献   
988.
We summarize updated information about DNA microarray-based gene expression profiling by focusing on its application to estrogenic chemicals. First, estrogenic chemicals, including natural/industrial estrogens and phytoestrogens, and the methods for detection and evaluation of estrogenic chemicals were overviewed along with a comprehensive list of estrogenic chemicals of natural or industrial origin. Second, gene expression profiling of chemicals using a focused microarray containing estrogen-responsive genes is summarized. Third, silent estrogens, a new type of estrogenic chemicals characterized by their estrogenic gene expression profiles without growth stimulative or inhibitory effects, have been identified so far exclusively by DNA microarray assay. Lastly, the prospect of a microarray assay is discussed, including issues such as commercialization, future directions of applications and quality control methods.  相似文献   
989.
红枣成熟期的裂果,是影响产质产量的主要问题之一.引起红枣裂果最直接的外部因素是成熟期的连阴雨.文章针对红枣裂果的气侯环境作出研究,并总结出采取棚盖、覆膜、喷药、套袋等措施进行防御,对保证产质产量,收到了较好效果.  相似文献   
990.
This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号