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91.
92.
The human pan-leukocyte antigen Leu-8 has attracted wide interest because its presence or absence identifies suppressor-inducer and helper-inducer CD4+ T-lymphocyte subsets respectively. We report here that Leu-8 is the human homologue of the mouse Mel-14 homing receptor, a molecule that promotes the initial adhesion of blood-borne lymphocytes to the specialized post-capillary endothelium of peripheral lymph nodes. We also show that Leu-8 can adopt both conventional and phospholipid anchored forms, a finding that may have relevance in the context of antigen shedding following activation or homing. The assignment of lymphocytes to different functional classes based on lymph node homing potential may represent a more general association between lymphocyte function and tissue distribution. 相似文献
93.
No evidence for expression of the insulin-regulatable glucose transporter in endothelial cells 总被引:6,自引:0,他引:6
A major effect of insulin is to increase glucose transport in muscle and fat. A family of genes encoding distinct mammalian glucose transporters has recently been elucidated. One of these, the insulin-regulatable glucose transporter (IRGT), is primarily expressed in muscle and fat, tissues that exhibit insulin-dependent glucose transport. Insulin promotes glucose transport in these tissues by stimulating movement of the glucose transporter from an intracellular location to the plasma membrane. Recent studies, however, suggest that an additional effect of insulin in these tissues may be the facilitation of glucose transport, presumably across capillary endothelium. This hypothesis is based on the localization of the IRGT in endothelial cells specific to muscle and adipose tissue. We report here, however, on morphological and biochemical studies using several different IRGT-specific antibodies in which we could not reproduce these results. 相似文献
94.
J.J.塔特赛尔 《国外科技新书评介》2007,(2):1-1
本书是初等数论的引论,供大学数学系高年级学生用作一学期的教材,其前身是作者在美国Providence学院和西点军校的讲稿。第二版对原版作了全面增订,增加了历史材料,强调了初等数论的应用,并添加了375道习题。 相似文献
95.
The strategic roles of modern business leaders are both demanding and diversified. Leaders all around the world are tied up with daily schedules, public as well as private. But it is almost self-evident that they should come out from all these trivial items and only focus on three key things: Strategic thinking and decision-making, branding position of their orga- nization and quality and long-term sustainability of core service of business. Business schools and programs all around the world are tapping into this mar- keting opportunity and try to free business leaders from daily tie-ups and really pay attention to the above-mentioned agenda. 相似文献
96.
James A. Jensen 《西北部美国博物学家》2011,45(4)
From 1972 to 1982 three exceptionally large sauropod scapulocoracoids and other equally large sauropod bones were collected from the base of the Brushy Basin Member of the Upper Jurassic, Morrison Formation, in western Colorado. Two of the scapulae are conspecific, but the third represents a second genus and possibly a new family. The two conspecific specimens are described here as: Supersaurus vivianae ; the second genus is described as Ultrasaurus mcintoshi , and a large, robust anterior dorsal vertebra of unique form is described as Dystylosaurus edwini . Various miscellaneous elements are referred to the three genera. 相似文献
97.
A radiation hybrid map of the rat genome containing 5,255 markers. 总被引:17,自引:0,他引:17
T K Watanabe M T Bihoreau L C McCarthy S L Kiguwa H Hishigaki A Tsuji J Browne Y Yamasaki A Mizoguchi-Miyakita K Oga T Ono S Okuno N Kanemoto E Takahashi K Tomita H Hayashi M Adachi C Webber M Davis S Kiel C Knights A Smith R Critcher J Miller T Thangarajah P J Day J R Hudson Y Irie T Takagi Y Nakamura P N Goodfellow G M Lathrop A Tanigami M R James 《Nature genetics》1999,22(1):27-36
A whole-genome radiation hybrid (RH) panel was used to construct a high-resolution map of the rat genome based on microsatellite and gene markers. These include 3,019 new microsatellite markers described here for the first time and 1,714 microsatellite markers with known genetic locations, allowing comparison and integration of maps from different sources. A robust RH framework map containing 1,030 positions ordered with odds of at least 1,000:1 has been defined as a tool for mapping these markers, and for future RH mapping in the rat. More than 500 genes which have been mapped in mouse and/or human were localized with respect to the rat RH framework, allowing the construction of detailed rat-mouse and rat-human comparative maps and illustrating the power of the RH approach for comparative mapping. 相似文献
98.
Henry Rogers Durkee collected 74 egg sets of 27 avian species in 1870 at Gilmer, Uinta County, in southwestern Wyoming. Despite the paucity of documented breeding evidence from this region during the late 19th and early 20th centuries, his material at the Smithsonian Institution was generally overlooked and has never been critically examined. Durkee's egg sets included 5 species (Sandhill Crane, Grus candensis ; Northern Rough-winged Swallow, Stelgidoteryx serripennis ; Grasshopper Sparrow, Ammodramus savannarum ; Fox Sparrow, Passerella iliaca ; Cassin's Finch, Carpodacus cassinii ) whose breeding distribution was then poorly known, 25 to more than 70 years before nests and eggs were otherwise documented in Wyoming. Durkee also collected complete egg sets of Lark Bunting ( Calamospiza melanocorys ) over 70 years before breeding was confirmed at other peripheral locations in Wyoming. In addition, Durkee's incomplete egg sets of Grasshopper Sparrow were the 1st western subspecies ( A. s. perpallidus ); his complete egg set and nest of the Fox Sparrow collected at Gilmer constituted the 2nd locality for the species or species group ( P. i. schistacea ). Although the number of egg sets Durkee collected is modest, he made a meaningful contribution to the early history of avifaunal exploration in Wyoming. 相似文献
99.
James J. Farrar 《西北部美国博物学家》2011,59(4)
Arabis pulchra plants infected by the crucifer rust fungus ( Puccinia consimilis ) develop pseduoflowers. These pseudoflowers are characterized by stems with short internodes and numerous closely spaced, bright yellow leaves coated with a sweet sugary substance. Pseudoflowers do not resemble normal A. pulchra flowers. Pseudoflowers, leaves, and stems of A. pulchra plants infected with P. consimilis and true flowers, stems, and leaves of uninfected A. pulchra plants were fixed, embedded, sectioned, and stained using standard microtechniques. Epidermal, ground, and vascular tissues of true leaves, true petals and pseudopetals were examined and compared for anatomic differences. Examination of anatomic characteristics revealed that pseudopetals are modified leaves. 相似文献
100.
Carbon isotope discrimination (Δ) was measured for leaves of Atriplex confertifolia along a salinity gradient in northern Utah. Over this gradient, the variation of Δ values was high for a C 4 species, and the Δ values were positively correlated with salinity in both years of study. Of the possible explanations for this patter, the Δ results are consistent with the notion that salinity induces an increase in the bundle sheath leakiness of these C 4 plants. 相似文献