中部地区教育投资效应实证分析

利用面板数据模型着重分析中部地区之间教育投资效应差异及其原因.得出结论:由于对教育的投资力度不同,导致了中部地区发展的不平衡.     

论《沧浪诗话》的“师古”思想体系及其得失

本文从师法的对象——“以汉魏晋盛唐为师”、师法的原因——“盛唐诸人惟在兴趣”和师法的方法——从“识”到“妙悟”三个角度对严羽《沧浪诗话》“师古”思想体系进行了梳理和阐发,并对之作出了准确的特点、原创的意义和超越性的价值等正面评价以及矛盾、错讹和疏漏的负面评价。     

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia

Hypertriglyceridemia is a hallmark of many disorders, including metabolic syndrome, diabetes, atherosclerosis and obesity. A well-known cause is the deficiency of lipoprotein lipase (LPL), a key enzyme in plasma triglyceride hydrolysis. Mice carrying the combined lipase deficiency (cld) mutation show severe hypertriglyceridemia owing to a decrease in the activity of LPL and a related enzyme, hepatic lipase (HL), caused by impaired maturation of nascent LPL and hepatic lipase polypeptides in the endoplasmic reticulum (ER). Here we identify the gene containing the cld mutation as Tmem112 and rename it Lmf1 (Lipase maturation factor 1). Lmf1 encodes a transmembrane protein with an evolutionarily conserved domain of unknown function that localizes to the ER. A human subject homozygous for a deleterious mutation in LMF1 also shows combined lipase deficiency with concomitant hypertriglyceridemia and associated disorders. Thus, through its profound effect on lipase activity, LMF1 emerges as an important candidate gene in hypertriglyceridemia.     

术语规范化是发展科技的一个关键问题——访我国著名语言文字学家周有光先生

他曾两次与爱因斯坦面对面，他是沈从文眼中的“周百科”，他参与制订《汉语拼音方案》，主持《汉语拼音正词法基本规则》的制订，他83岁告别纸笔学电脑，百岁出新著，月月有新稿，他功成于经济却名就于语文，其经济学和语言文字学著作被同时陈列于美国国会图书馆，供来自世界各国的学者查阅。他就是周有光先生，我国著名语言文字学家。     

Common Molecular Mechanisms of Mammary Gland Development and Breast Cancer

During its lifetime, the mammary gland undergoes many phases of development and differentiation. Much of this occurs during puberty, when the ductal epithelium expands by branching morphogenesis, invading the surrounding fat pad to form an organised mammary tree. Throughout its existence, the epithelium will go through several cycles of proliferation and cell death during pregnancy, lactation and involution. Many of the signalling mechanisms which control the initial invasion of the fat pad by the epithelium, and regulate its continuing plasticity, can be harnessed or corrupted by tumour cells in order to support their aberrant growth and progression towards invasion. This is true not just for the epithelial cells themselves but also for cells in the surrounding microenvironment, including fibroblasts, macrophages and adipocytes. This review examines the complex web of signalling and adhesion interactions controlling branching morphogenesis, and how their alteration can promote malignancy. Current in vivo and in vitro mammary gland models are also discussed. (Part of a Multi-author Review)     

《计算机组成原理》（运算器）多媒体模拟实验教学

介绍如何应用计算机设计《计算机组成原理》的实验教学，应用C 编写功能函数来模拟各种芯片的工作，使同学们在学习中更直观的了解芯片的工作。所介绍的程序是对运算功能发生器(74LS181)的模拟编程，完成32种算术逻辑运算实验。     

道路照明节电方法的应用与分析

阐述了路灯节电方法的应用，并对节电方法的经济性进行了分析，展望了绿色照明的前景。     

Which survey indicators are useful for monitoring consumption? Evidence from European countries

This paper assesses the information content of two survey indicators for consumption developments in the near future for eight European countries in the period 1985–1998. Empirical work on this topic typically focuses on consumer confidence, the perceptions of buyers of consumption goods. This paper examines whether perceptions of sellers of consumption goods, measured by retail trade surveys, may also improve short‐term monitoring of consumption. We find that both consumer confidence and retailer confidence embody valuable information, when analysed in isolation. For France, Italy and Spain we conclude that adding retail confidence does not improve the indicator model once consumer confidence has been included. For the UK the reverse case is obtained. For the remaining four countries we show that combining consumer sentiment and retail trade confidence into a composite indicator leads to optimal results. Our results suggest that incorporating information from retail trade surveys may offer significant benefits for the analysis of short‐term prospects of consumption. Copyright © 2004 John Wiley & Sons, Ltd.