弘扬国学精粹 提高人文素质--高校非中文专业开设"中国古典文学鉴赏"课的必要性与可行性

从高校非中文专业学生知识结构的现状出发，阐述加强人文素质教育的重要性；“中国古典文学鉴赏”课的课程特点及其在人文素质教育中所起的作用决定了在高校非中文专业学生中开设这门课程的必要性和可行性。     

Sound communication inNezara viridula (L.) (Heteroptera: Pentatomidae): Further evidence that signal transmission is substrate-borne

We investigated the sound communication associated with mating inNezara viridula (L.) to clarify conflicting reports on the medium through which acoustic signals are borne. Recordings made from virgin pairs ofN. viridula during precopulatory and compulatory behaviour have revealed that signals transmitted as vibrations through the substrate are a more likely means of communication than signals transmitted by a radiation of sound pressure waves through the air (at least in Australian populations). We present evidence (additional to that already in the literature) that air-borne acoustics are an unlikely mechanism of sexual communication in this species. Specifically, the recorded pulse train patterns showed no consistency or repeatability in relation to different stages of mating behaviour. In contrast, frequency spectrograms of substrate-borne signals reveal repeatable patterns that do correspond with the stage of mating behaviour.     

Aspirin-like drugs may block pain independently of prostaglandin synthesis inhibition

Summary Using flurbiprofen, a chiral anti-inflammatory and analgesic 2-arylpropionic acid derivative, the enantiomers of which are not converted to each other (less than 5%) in rats or man, we obtained evidence that prostaglandin synthesis inhibition is primarily mediating the anti-inflammatory activity but prostaglandin synthesis independent mechanisms contribute to the analgesic effects. Thus, the S-form inhibited prostaglandin synthesis, inflammation and nociception in rats. The R-form had much less effect on prostaglandin synthesis and did not affect inflammation. It did, however, block nociception in rats almost as potently as the S-form. S-flurbiprofen, in contrast to the R-form, was clearly ulcerogenic in the gastrointestinal mucosa. These results indicate additional molecular mechanisms of analgesia and suggest the use of R-arylpropionic acids as analgesics.     

激光开槽、埋槽电极硅太阳电池

报道一种新颖的激光开槽、埋槽电极硅太阳电池的结构、工艺流程及其研制结果。在ＡＭ１．５，２５℃，１００ｍＷ／ｃｍ２的条件下，以面积为４５ｃｍ３的３６片硅片研制的硅太阳电池的输出参数的平均值为ＪＳＣ＝３６．１ｍＡ／ｃｍ２，Ｖ∞＝６３３ｍＶ，Ｆ．Ｆ．＝０．７９８，η＝１８．２３％，最后分析了种高性能硅太阳电池的设计特点。     

Purealidin A,a new cytotoxic bromotyrosine-derived alkaloid from the Okinawan marine spongePsammaplysilla purea

Summary A new bromotyrosine-derived alkaloid with antileukemic activity, purealidin A (5), has been isolated from the Okinawan marine spongePsammaplysilla purea and its chemical structure elucidated on the basis of the spectroscopic data.     

Memory

Memories become stabilized through a time-dependent process that requires gene expression and is commonly known as consolidation. During this time, memories are labile and can be disrupted by a number of interfering events, including electroconvulsive shock, trauma and other learning or the transient effect of drugs such as protein synthesis inhibitors. Once consolidated, memories are insensitive to these disruptions. However, they can again become fragile if recalled or reactivated. Reactivation creates another time-dependent process, known as reconsolidation, during which the memory is restabilized. Here we discuss some of the questions currently debated in the field of memory consolidation and reconsolidation, the molecular and anatomical requirements for both processes and, finally, their functional relationship.     

Understanding the importance of selenium and selenoproteins in muscle function

Selenium is an essential trace element. In cattle, selenium deficiency causes dysfunction of various organs, including skeletal and cardiac muscles. In humans as well, lack of selenium is associated with many disorders, but despite accumulation of clinical reports, muscle diseases are not generally considered on the list. The goal of this review is to establish the connection between clinical observations and the most recent advances obtained in selenium biology. Recent results about a possible role of selenium-containing proteins in muscle formation and repair have been collected. Selenoprotein N is the first selenoprotein linked to genetic disorders consisting of different forms of congenital muscular dystrophies. Understanding the muscle disorders associated with selenium deficiency or selenoprotein N dysfunction is an essential step in defining the causes of the disease and obtaining a better comprehension of the mechanisms involved in muscle formation and maintenance. Received 13 July 2005; received after revision 9 September 2005; accepted 4 October 2005     

Common deletion polymorphisms in the human genome

The locations and properties of common deletion variants in the human genome are largely unknown. We describe a systematic method for using dense SNP genotype data to discover deletions and its application to data from the International HapMap Consortium to characterize and catalogue segregating deletion variants across the human genome. We identified 541 deletion variants (94% novel) ranging from 1 kb to 745 kb in size; 278 of these variants were observed in multiple, unrelated individuals, 120 in the homozygous state. The coding exons of ten expressed genes were found to be commonly deleted, including multiple genes with roles in sex steroid metabolism, olfaction and drug response. These common deletion polymorphisms typically represent ancestral mutations that are in linkage disequilibrium with nearby SNPs, meaning that their association to disease can often be evaluated in the course of SNP-based whole-genome association studies.