Maize HapMap2 identifies extant variation from a genome in flux

Whereas breeders have exploited diversity in maize for yield improvements, there has been limited progress in using beneficial alleles in undomesticated varieties. Characterizing standing variation in this complex genome has been challenging, with only a small fraction of it described to date. Using a population genetics scoring model, we identified 55 million SNPs in 103 lines across pre-domestication and domesticated Zea mays varieties, including a representative from the sister genus Tripsacum. We find that structural variations are pervasive in the Z. mays genome and are enriched at loci associated with important traits. By investigating the drivers of genome size variation, we find that the larger Tripsacum genome can be explained by transposable element abundance rather than an allopolyploid origin. In contrast, intraspecies genome size variation seems to be controlled by chromosomal knob content. There is tremendous overlap in key gene content in maize and Tripsacum, suggesting that adaptations from Tripsacum (for example, perennialism and frost and drought tolerance) can likely be integrated into maize.     

A SIMPLIFIED APPROACH TO EMBEDDING PROBLEMS IN NORMAL BORDISM FRAMEWORK

The purpose of this paper is to simplify the computations of the nor-mal bordism groups Ω_i(W_f,M×P~∞;(?))and Ω_i(C_f,(?)w;θ_f)which Salomonsenand Dax introduced respectively to study the existence and isotopy classificationof differential embeddings of manifolds in manifolds in the metastable range.Asimpler space pair(K_f,M×P~∞)is constructed to replace(W_f,M×P~∞).It isshown that(K_f,M×P~∞)is homotopy equivalent to(W_f,M×P~∞)and homotopy(n-1)-equivalent to(C_f,(?)W).To demonstrate the efficacy of this simplification,the isotopy groups [M~n(?)RP~(n+k)],if n(?)2k-4 and M~n is a closed(n-k+2)-connected manifold,and[M~n(?)L(p;q_1…,q_m)],if 3n(?)4m-2,M~n is a closed(2n-2m+1)-connected manifold and L is a (2m+1)-dimensional lens space,arespecifically computed.     

Diagnosis of prostate cancer by quantitative analysis of 3DMRSI data: A new model

Prostatecancer (PC)hasthehighestmorbidityrateinmaleurinarysystemdisordersinEuropeandAmerica ,anditisoneoftheprimaryreasonsofmaledeath[1] .InChina ,althoughtheattackofPCisrela tivelylow ,ithasa growingtrendinrecent 10years[2— 4 ] .Inclinicalpractice ,magneticresonanceimaging (MRI)could providehighresolutionmor phologicalstructureandhasthecapabilityofmulti parameterimaging ,butitcannotreliablydifferentiatePCfrombenignprostatehyperplasia (BPH)andnor maltissues ,particularlyforthepatientswi…     

環繞華盛頓的雙邊協定

美國和西歐十六國(以及中國)簽訂的雙邊協定,是馬歇爾計劃結晶化的文件。馬歇爾計劃經過美國國會辯論成立法案以後,歐洲復興計劃(ERP)成爲各國內政的一部份,以霍夫曼為主持人的經濟合作總署(ECA)成為各國政府的最高監督。各受援國在經濟上成為美國公司的分公司,在政治上成為託管殖民地。這些雙邊協定是以華爾街的利益爲總方針的。美國避免和各受援國簽訂互有義務的多邊協定,正是為了避免造成集體的反對。個別的     

A high-sensitive detection method for carvone odor by implanted electrodes in rat olfactory bulb

Mammalian olfactory systems have extraordi- nary ability to sense and identify various trace odorants. Taking advantages of cell culture and micro-fabrication technologies, olfactory cell- or tissue-based biosensor represent a promising platform for in vitro odorant detec- tion. However, in vitro conditions lead to shortened cell/ tissue survivals, and the working life of neuron chips is short. The purpose of this study is to develop an in vivo recording and analyzing method for long-term and repeatable detection of odor stimulation. In this study, we implanted penetrating micro-wire array electrode into the olfactory bulb of conscious rats to obtain odor-evoked electrophysiological activities. Then, we investigated the response of ensembles of mitral/tufted cells to stimulation with carvone at a number of concentrations in time and frequency domains. The stable, repeatable odorant responses from up to 16 neural regions could be obtained for at least 3 weeks. Further, we explored the concentration detection sensitivity limitation of developed method, and found the detection low limit of carvone was below 10-a~ mol/L. The result demonstrates that the concentra- tion range of in vivo odorant detection method is much wider than in vitro method.     

EXISTENCE OF AUTHENTICATION CODES

1.IntroductionLetS,e,andMbethreenon--emptysetsandletf:Sxe-- Mbeamap;thefourtuple(S,E,M;f)iscalledanauthenticationcoded],if1)Themapf:Sxe-Missurjectiveand2)ForanymEMandeEE,ifthereisansESsatisfyingf(s,e)=m,thensuchansisuniquelydeterminedbythegivenmande...     

商品住宅每户建筑面积计算方法的建议

近几年来,福利型和行政分配模式的公有住房,逐步商品化。商品化住宅以其建筑标准、面积大小、户型种类、层数高低乃至方位朝向、环境条件、外部造型等,无不体现商品住宅的市场价格。因为商品房价格是由以上诸因素确定的。但在房地产交易中,商品房价格是按各户建筑面积...     

Multi-index analysis of the melting process of laterite metallized pellet

Herein, a multi-index analysis of the nickel content of an alloy, output rate of the alloy, nickel recovery rate, and iron recovery rate during the melting of laterite metallized pellets was performed. The thermodynamic reduction behavior of oxides such as NiO, FeO, Fe₃O₄, and Cr₂O₃ was studied using the FactSage software, which revealed that SiO₂ is not conducive to the reduction of iron oxides, whereas the addition of basic oxides such as CaO and MgO is beneficial for the reduction of iron oxides. On the basis of a comprehensive analysis to achieve greater nickel recovery and lower iron recovery rates, the optimum experimental parameters in the orthogonal experiment were A3B1C3 (t=30 min, C/O=0.4, R=1.2); the indicators w_Ni, φ_alloy, η_Ni, and η_Fe had values of 15.0wt%, 12.1%, 44.9%, and 96.4%, respectively. In single-factor experiments, increasing basicity (R) substantially improved the separation effect in the low-basicity range 0.5 ≤ R ≤ 0.8 but not in the high-basicity range 0.8 ≤ R ≤ 1.2. Similar results were obtained for the effect of the C/O ratio. Moreover, the recovery rate of nickel increased with increasing recovery rate of iron.     

FICW： Frequent Itemset Based Text Clustering with Window Constraint

Most of the existing text clustering algorithms overlook the fact that one document is a word sequence with semantic information. There is some important semantic information existed in the positions of words in the sequence. In this paper, a novel method named Frequent Itemset-based Clustering with Window （FICW） was proposed, which makes use of the semantic information for text clustering with a window constraint. The experimental results obtained from tests on three （hypertext） text sets show that FICW outperforms the method compared in both clustering accuracy and efficiency.