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排序方式: 共有6666条查询结果,搜索用时 15 毫秒
41.
42.
FROM MANUFACTURING SCHEDULING TO SUPPLY CHAIN COORDINATION:THE CONTROL OF COMPLEXITY AND UNCERTAINTY
Peter B.LUH 《系统科学与系统工程学报(英文版)》2003,12(3):279-297
With time-based competition and rapid technology advancements, effective manufacturingscheduling and supply chain coordination are critical to quickly respond to changing marketconditions. These problems, however, are difficult in view of inherent complexity and variousuncertainties involved. Based on a series of results by the authors, decomposition and coordination byusing Lagrangian relaxation is identified in this paper as an effective way to control complexity anduncertainty.A manufacturing scheduling problem is first formulated within the job shop context withuncertain order arrivals, processing times, due dates, and part priorities as a separable optimizationproblem. A solution methodology that combines Lagrangian relaxation, stochastic dynamicprogramming, and heuristics is developed. Method improvements to effectively solve large problemsare also highlighted. To extend manufacturing scheduling within a factory to coordinate autonomicmembers across chains of suppliers, a decentralized supply chai 相似文献
44.
日本的政体是议会内阁制。第二次世界大战前日本是天皇集权制,二战后变为议会制君主国。据1947年5月3日施行的《日本国宪法》,行政权属于内阁,国会是国家的最高权力机关,也是国家唯一的立法机关,天皇只是国家和国民整体的象征,并且天皇的“地位以主权所在的全体日本国民的意志为依据”,天皇只能行使宪法所规定的有关国事行为,“并无关于国政的权能”。日本实行政党政治,除自民党外,还有所谓三大在野党,即:社会党,1945年11月成立,现任中央执行委员长山花贞夫;公明党,1964年11月成立,现任中央执行委员长石田幸四郎;民社党,1960年1月成立,现任中央执行委员长大内启伍。此外,社会民主联合(简称“社民联”)也 相似文献
45.
46.
Dina C Meyre D Gallina S Durand E Körner A Jacobson P Carlsson LM Kiess W Vatin V Lecoeur C Delplanque J Vaillant E Pattou F Ruiz J Weill J Levy-Marchal C Horber F Potoczna N Hercberg S Le Stunff C Bougnères P Kovacs P Marre M Balkau B Cauchi S Chèvre JC Froguel P 《Nature genetics》2007,39(6):724-726
We identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset and severe obesity in both adults and children of European ancestry with an experiment-wise P value of 1.67 x 10(-26) in 2,900 affected individuals and 5,100 controls. The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses. 相似文献
47.
tRNase Z: the end is not in sight 总被引:1,自引:0,他引:1
Although the enzyme tRNase Z has only recently been isolated, a plethora of data has already been acquired concerning the
enzyme. tRNase Z is the endonuclease that catalyzes the removal of the tRNA 3′ trailer, yielding the mature tRNA 3′ end ready
for CCA addition and aminoacylation. Another substrate cleaved by tRNase Z is the small chromogenic phosphodiester bis(p-nitrophenyl)phosphate (bpNPP), which is the smallest tRNase Z substrate known so far. Hitherto the biological function as
tRNA 3′-end processing enzyme has been shown only in one prokaryotic and one eukaryotic organism, respectively. This review
summarizes the present information concerning the two tRNase Z substrates pre-tRNA and bpNPP, as well as the metal requirements
of tRNase Z enzymes.
Received 29 March 2007; received after revision 15 May 2007; accepted 21 May 2007 相似文献
48.
2006年12月8日至10日,由中国自然辩证法研究会方法论委员会、武汉商贸学院和武汉东湖高新技术工业园联合举办的第五届全国科学方法论学术讨论会在武汉举行。来自全国各地的47名专家学者参加了讨论。其中,有近20名学者在会议上做了主题发言。 相似文献
49.
对于两个变量的多项式环中的理想,我们给出了其有限生成基个数的一个最小上界的估计.并由例子说明此估计是最佳的. 相似文献
50.
Dhar-Chowdhury P Malester B Rajacic P Coetzee WA 《Cellular and molecular life sciences : CMLS》2007,64(23):3069-3083
Glycolysis is an evolutionary conserved metabolic pathway that provides small amounts of energy in the form of ATP when compared
to other pathways such as oxidative phosphorylation or fatty acid oxidation. The ATP levels inside metabolically active cells
are not constant and the local ATP level will depend on the site of production as well as the respective rates of ATP production,
diffusion and consumption. Membrane ion transporters (pumps, exchangers and channels) are located at sites distal to the major
sources of ATP formation (the mitochondria). We review evidence that the glycolytic complex is associated with membranes;
both at the plasmalemma and with membranes of the endo/sarcoplasmic reticular network. We examine the evidence for the concept
that many of the ion transporters are regulated preferentially by the glycolytic process. These include the Na+/K+-ATPase, the H+-ATPase, various types of Ca2+-ATPases, the Na+/H+ exchanger, the ATP-sensitive K+ channel, cation channels, Na+ channels, Ca2+ channels and other channels involved in intracellular Ca2+ homeostasis. Regulation of these pumps, exchangers and ion channels by the glycolytic process has important consequences
in a variety of physiological and pathophysiological processes, and a better understanding of this mode of regulation may
have important consequences for developing future strategies in combating disease and developing novel therapeutic approaches.
Received 20 July 2007; received after revision 30 July 2007; accepted 17 August 2007 相似文献