Kinins and kininogen in endotoxin shock

Résumé Aucune quantité détectable de kinines ne fut trouvée après administration d'endotoxine et l'on n'obtint pas de différence significative dans le contenu plasmatique en kininogènes après l'injection. Nos résultats n'attribuent aux kinines aucune participation significative à l'hypotension du choc endotoxique.

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Supported in part by a grant of the Consejo Nacional de Investigaciones Científicas y Técnicas (CNICT), Argentina.     

Zur zellulären Aminosäure-Inkorporation im in- und exkretorischen Pankreas unter experimentellen Bedingungen

Summary After glucagon and tolbutamide administration, the protein synthesis in the nucleus increases, especially in the B- but to a lesser extent also in the A-cells. Similar effects are noted in the cytoplasma of B-cells. Already 2 h following alloxan premedication, there is no activity in the nucleus and cytoplasm of B-cells, whereas in the A-cells they are markedly labelled.     

Use of a zonal rotor for demonstrating that human myelin is formed by a continuum of particles of different densities]

Human myelin isolated from frozen brain consists of a continuum of particles as shown by sucrose continuous gradient (between 0,4 and 0,85 M) on zonal rotor. This was determined by measuring the O. D. at 260 and 280 millimicron, the protein concentration by Lowry method and sucrose concentration by polarimetry in 60 fractions. Most of the material is concentrated between 20-23% sucrose, the maximum being found at 21.5% (0.63 M). The fractions are dialyzed for 62 hrs. to remove the sucrose and the pellet obtained after centrifugation shows that the protein concentration increases from the ligher fraction to the heavier.