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991.
C.H.陈 《国外科技新书评介》2006,(12):11-12
本书的第一、二、三版分别于1993、1999和2005年出版。书中全面提供了过去20年中在模式识别与计算机视觉领域中的进展和成就,作者都是这个领域的第一流专家,其中的两位Thomas Huang和Jake Aggarwal是权威的K.S.Fu奖金获得者,该项奖金是由国际模式识别协会(IAPR)授予。 相似文献
992.
993.
本书全面论述了传输、管理和控制位面的技术,介绍了一些有用的、现行的和下一代电讯网络技术的参考信息。四位作者均在电信学研究、产品开发等方面具有20年以上的经验。 相似文献
994.
Galectin-7 总被引:4,自引:0,他引:4
Galectins are a family of animal lectins with an affinity for β-galactosides. They are differentially expressed by various
tissues and appear to be functionally multivalent, exerting a wide range of biological activities both during development
and in adult tissue. Galectin-7, a member of this family, contributes to different events associated with the differentiation
and development of pluristratified epithelia. It is also associated with epithelial cell migration, which plays a crucial
role in the re-epithelialization process of corneal or epidermal wounds. In addition, recent evidence indicates that galectin-7,
designated as the product of the p53-induced gene 1 (PIG1), is a regulator of apoptosis through JNK activation and mitochondrial
cytochrome c release. Defects in apoptosis constitute one of the major hallmarks of human cancers, and galectin-7 can act
as either a positive or a negative regulatory factor in tumour development, depending on the histological type of the tumour.
Received 30 October 2005; received after revision 15 November 2005; accepted 25 November 2005 相似文献
995.
J C Chabala V B Waits T Ikeler A A Patchett L Payne L H Peterson R A Reamer K Hoogsteen M Wyvratt W L Hanson 《Experientia》1991,47(1):51-53
1-(Substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors of Trypanosoma cruzi infections in mice. The most active compounds are the 1-(4-chlorobenzyl)- and 1-(3,4-dichlorobenzyl)-analogs (L-153,094 [2] and L-153,153 [4], resp.) which are approximately 7-fold more potent upon oral administration than nifurtimox (Lampit) in suppressing parasite levels in the blood of mice with acute Trypanosoma cruzi infections. 相似文献
996.
Glucose/galactose malabsorption (GGM) is an autosomal recessive disease manifesting within the first weeks of life and characterized by a selective failure to absorb dietary glucose and galactose from the intestine. The consequent severe diarrhoea and dehydration are usually fatal unless these sugars are eliminated from the diet. Intestinal biopsies of GGM patients have revealed a specific defect in Na(+)-dependent absorption of glucose in the brush border. Normal glucose absorption is mediated by the Na+/glucose cotransporter in the brush border membrane of the intestinal epithelium. Cellular influx is driven by the transmembrane Na+ electrochemical potential gradient; thereafter the sugar moves to the blood across the basolateral membrane via the facilitated glucose carrier. We have previously cloned and sequenced a Na+/glucose cotransporter from normal human ileum and shown that this gene, SGLT1, resides on the distal q arm of chromosome 22. We have now amplified SGLT1 complementary DNA and genomic DNA from members of a family affected with GGM by the polymerase chain reaction. Sequence analysis of the amplified products has revealed a single missense mutation in SGLT1 which cosegregates with the GGM phenotype and results in a complete loss of Na(+)-dependent glucose transport in Xenopus oocytes injected with this complementary RNA. 相似文献
997.
从一种超声模拟测井记录的井下信号、深度信号送微机处理的实际要求出发,分析井下信号数据采集的工作原理,阐述了与12位A/D转换器实时配套工作的双存储体工作时序。通过对深度信号的解调,提出了一种解决4FSK解调的有效方法。 相似文献
998.
从BP网络对信息存储的分布式特点出发,分析了连接权系数及输入变化对输出的影响,探讨了BP网络的容错性及抗干扰特性,得出了一些有益的结论。 相似文献
999.
Viable metacyclic forms of T. cruzi, Y strain, treated with an adequate dose of actinomycin D (50 micrograms Act-D/ml/10(7) parasites/ml for 72 h at 28 degrees C) showed the following properties: 1) they lost their ability to replicate in culture medium, in blood and in tissues of normal mice and were no longer able to incorporate tritiated thymidine; 2) they could not penetrate into Vero cells and could not replicate inside normal macrophages; 3) they retained their immunogenicity and the ability to protect mice against a virulent infection; 4) they did not induce histological lesions as described in chronic experimental Chagas' disease. 相似文献
1000.
Niimura N Arai S Kurihara K Chatake T Tanaka I Bau R 《Cellular and molecular life sciences : CMLS》2006,63(3):285-300
Neutron diffraction provides an experimental method of directly locating hydrogen atoms in proteins, a technique complimentary to ultra-high-resolution [1, 2] X-ray diffraction. Three different types of neutron diffractometers for biological macromolecules have been constructed in Japan, France and the United States, and they have been used to determine the crystal structures of proteins up to resolution limits of 1.5-2.5 A. Results relating to hydrogen positions and hydration patterns in proteins have been obtained from these studies. Examples include the geometrical details of hydrogen bonds, H/D exchange in proteins and oligonucleotides, the role of hydrogen atoms in enzymatic activity and thermostability, and the dynamical behavior of hydration structures, all of which have been extracted from these structural results and reviewed. Other techniques, such as the growth of large single crystals, the preparation of fully deuterated proteins, the use of cryogenic techniques, and a data base of hydrogen and hydration in proteins, will be described. 相似文献