U.S. agrigenetics: suit filed against NIH

Three environmental groups have filed suit against the National Institutes of Health in an attempt to block an experiment approved in April by the NIH Recombinant DNA Advisory Committee. The experiment, designed by researchers at the University of California, Berkeley, to enhance the frost resistance of crops, would release genetically engineered organisms into the general environment for the first time. The suit, filed in a federal court in the District of Columbia, claims that releasing frost-resistant bacteria into the environment could have damaging ecological consequences, that NIH should have issued an environmental impact assessment before approving any experiment involving the release of genetically engineered organisms, and that the Recombinant DNA Advisory Committee lacks the expertise to assess environmental risks.     

用cpDNA matK基因和nrDNA ITS区序列确定我国特有植物四棱草属的系统位置

测定了我国特有植物四棱草属以及马鞭草科6属和唇形科13属共27个代表种的叶绿体DNA matK基因和核核糖体DNA ITS区序列.应用相对表观衍征分析方法(RASA)对所测DNA序列的系统发育信号及所选择外类群的有效性进行了统计评价.应用最大简约法(MP)、邻接法(NJ)和最大似然法 (ML)对matK和ITS序列进行了独立的和联合的分子系统发育分析.结果表明,四棱草与三花莸为姐妹群;Contino等提出的莸属复合群不构成单系类群,莸属4种具有复系演化关系;Contino系统中的筋骨草亚科形成一个单系分支.此外,本文结果支持马鞭草科与唇形科构成复系类群以及白骨壤属从马鞭草科中独立的观点.RASA分析和多基因联合分析为确定复杂类群间的系统发育关系提供了有效的途径.     

Heat Transfer Enhancement Due to Marangoni Flow Around Moving Bubbles During Nucleate Boiling

Introduction Nucleate boiling has always been an important heat transfer mechanism in many fields, such as energy utilization, manufacturing processes, and chemical processing and nucleate boiling continues to find new applications in many new areas, such…     

数字通信系统 第三版

本书全面介绍了数字通信系统的理论和实际应用方法，并且包含了在数字信号传输中需要运用的关于设计、实现和测试的最新方法和技术。此书介绍的基本技术有：纠错码、多路复用、数字调制、数字用户线路、电缆调制、移动无线网络、城域网和光纤网络。新的工业标准有：声音／视频编码、SONET/SDH、DWDM、ATM、宽带无线网、网络同步和网络管理。每一章节后都有评述和参考文献和大量习题（无答案）。     

Melatonin transport into mitochondria

Melatonin is a well-known, nighttime-produced indole found in bacteria, eukaryotic unicellulars, animals or vascular plants. In vertebrates, melatonin is the major product of the pineal gland, which accounts for its increase in serum during the dark phase, but it is also produced by many other organs and cell types. Such a wide distribution is consistent with its multiple and well-described functions which include from the circadian regulation and adaptation to seasonal variations to immunomodulatory and oncostatic actions in different types of tumors. The discovery of its antioxidant properties in the early 1990s opened a new field of potential protective functions in multiple tissues. A special mention should be made regarding the nervous system, where the indole is considered a major neuroprotector. Furthermore, mitochondria appear as one of the most important targets for the indole’s protective actions. Melatonin’s mechanisms of action vary from the direct molecular interaction with free radicals (free radical scavenger) to the binding to membrane (MLT1A and MLT1B) or nuclear receptors (RZR/RORα). Receptor binding has been associated with some, but not all of the indole functions reported to date. Recently, two new mechanisms of cellular uptake involving the facilitative glucose transporters GLUT/SLC2A and the proton-driven oligopeptide transporter PEPT1/2 have been reported. Here we discuss the potential importance that these newly discovered transport systems could have in determining the actions of melatonin, particularly in the mitochondria. We also argue the relative importance of passive diffusion vs active transport in different parts of the cell.