论会计能力模块课程体系的设计与实施

针对会计教学改革的不断深入，提出了会计能力模块课程体系的设计思路，论述了会计能力模块开发的现实性，模块设计的原则，类型及教学研究与实施方法。     

高等学校学科知识联盟

借用企业知识联盟的一些思想,阐述了高校学科知识联盟的形式、意义以及构建方法。     

Tissue-specific and reversible RNA interference in transgenic mice

Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression, we have developed a simple transgenic system to reversibly control endogenous gene expression using RNA interference (RNAi) in mice. Transgenic mice harboring a tet-responsive RNA polymerase II promoter driving a microRNA-based short hairpin RNA targeting the tumor suppressor Trp53 reversibly express short hairpin RNA when crossed with existing mouse strains expressing general or tissue-specific 'tet-on' or 'tet-off' transactivators. Reversible Trp53 knockdown can be achieved in several tissues, and restoring Trp53 expression in lymphomas whose development is promoted by Trp53 knockdown leads to tumor regression. By leaving the target gene unaltered, this approach permits tissue-specific, reversible regulation of endogenous gene expression in vivo, with potential broad application in basic biology and drug target validation.     

浅谈预算编制改革与预算执行改革

针对传统预算编制方法与预算执行机制中存在的突出问题,浅谈如何同步推进预算编制改革与预算执行改革。     

流形上微分方程求解的渐近展开方法

文章陈述了流形上微分方程、渐近级数和渐近展开等概念和相关命题,然后给出了例子,用渐近展开方法求解了微分方程。     

素质教育在剑桥商务英语教学中的应用

在高等教育中，素质教育已经成为中国教育改革和人才培养的指导思想。只有重视素质教育，使科学教育与素质教育整合，才能培养出高科技与高素质相结合的专门人才服务于社会。剑桥商务英语教学中应用素质教育极大的提高了教学效果。通过应用素质教育，培养学生在掌握商务英语基本概念和词汇的基础上，提高学生解决实际商务问题的能力，引导他们全面地、辩证地思考问题，引导他们把书本知识和社会实践联系起来，重视实际斗争经验。     

高等院校教材管理信息系统的分析与设计实现

主要论述了我们为高等院校教材管理所开发的一套计算机管理信息系统的设计思想与实现方法,由于本系统具有使用方便、操作简单,安全稳定,工作流程清晰合理,并与用户熟悉的工作方式相一致,用户无需专业培训即可使用该系统进行工作等特点,因此,深受用户的欢迎。     

基于正六边形线阵CCD探测器的周视场目标探测系统

提出了一种基于正六边形线阵CCD探测器的运动目标探测系统.系统不仅可以实现360°范围内环形视场探测,还可以实时显示运动目标的位置及角速度信息,达到搜索跟踪的目的.在硬件设计方面,提出并实现了基于CPLD和AVR的电路方案.在算法设计方面,设计了适于周视场运动目标探测算法.     

Finding finer functions for partially characterized proteins by protein-protein interaction networks

Based on high-throughput data, numerous algorithms have been designed to find functions of novel proteins. However, the effectiveness of such algorithms is currently limited by some fundamental factors, including (1) the low a-priori probability of novel proteins participating in a detailed function; (2) the huge false data present in high-throughput datasets; (3) the incomplete data coverage of functional classes; (4) the abundant but heterogeneous negative samples for training the algorithms; and (5) the lack of detailed functional knowledge for training algorithms. Here, for partially characterized proteins, we suggest an approach to finding their finer functions based on protein interaction sub-networks or gene expression patterns, defined in function-specific subspaces. The proposed approach can lessen the above-mentioned problems by properly defining the prediction range and functionally filtering the noisy data, and thus can efficiently find proteins’ novel functions. For thousands of yeast and human proteins partially characterized, it is able to reliably find their finer functions (e.g., the translational functions) with more than 90% precision. The predicted finer functions are highly valuable both for guiding the follow-up wet-lab validation and for providing the necessary data for training algorithms to learn other proteins.     

新建地方院校实验室仪器设备管理工作探讨

分析了新建地方院校实验室仪器设备管理工作的特点和问题,探讨了加强仪器设备管理的措施。