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1.
研究了被动吸烟对小鼠生长性能及血液系统的影响.将小鼠分为雌、雄对照组和处理组,处理组小鼠进行烟熏处理,对照组常规饲养不做任何处理,120 d后进行生长性能、血常规和血液流变学指标测定.结果显示:接受烟熏120 d后,雌雄小鼠的体质量和体质量增长量均显著低于同性别对照组小鼠(P<0.01和P<0.05),且雌性处理组小鼠体质量和体质量增长量极显著低于雄性处理组小鼠(P<0.01);雌雄性处理组小鼠的红细胞数、血小板数和血红蛋白含量显著高于雌雄性对照组小鼠(P<0.01和P<0.05),但白细胞数没有统计学差异;雌雄性处理组小鼠的血浆粘度显著高于对照组小鼠(P<0.01),但全血粘度没有显著差异.以上结果提示被动吸烟可减缓小鼠的生长,改变小鼠的血常规指标和血浆粘度.  相似文献   

2.
目的:评估HSL基因敲除小鼠的学习记忆功能.方法:采用经典的Morris水迷宫实验,测试三种基因型小鼠的认知行为变化.结果:三种基因型小鼠的潜伏期几乎都逐渐缩短,雄性正常小鼠的潜伏期在1~2天,明显地短于HSL敲除小鼠(P<0.01);雌性正常小鼠的潜伏期在第3~5天,明显地短于HSL敲除小鼠(P<0.01),随后几天都无显著差异.第8天撤去平台,小鼠跨越原平台位置的次数无显著差异.结论:HSL敲除的小鼠都存在明显的认知水平功能障碍,雄性小鼠在前期差异显著,雌性小鼠在中期差异显著,但给予适当的学习训练后都能达到正常小鼠的认知水平.  相似文献   

3.
以昆明小鼠为研究对象,应用小鼠Y型迷宫实验的方法,以环磷酸腺苷(cAMP)为阳性对照,以达标所需训练次数/天数(TN/TD)、正确反应率(CRR)、全天总反应时间(TRT)、主动回避率(AAR)为评价指标,开展不同浓度牛奶乳清液对小鼠学习记忆能力影响的研究。结果表明:阳性对照较空白对照组可显著降低小鼠TN(P0.05),灌胃半个月后可显著降低小鼠TRT并显著提高AAR(P0.05),并且灌胃一个月以后对小鼠CRR有明显升高作用(P0.05);牛奶乳清液较空白对照组可显著降低小鼠TN/TD(P0.05),灌胃半个多月后可显著升高小鼠的CRR和AAR,显著降低小鼠TRT(P0.05);与阳性对照组相比较,牛奶乳清液对小鼠CRR影响不显著(P0.05),但可显著降低小鼠TN/TD,显著升高AAR(P0.05),对于灌胃2个月小鼠的TRT降低效果更好,而且均以3/4倍稀释的牛奶乳清液效果最佳。因此,牛奶乳清液具有一定促进小鼠学习记忆能力的作用。  相似文献   

4.
目的通过给小鼠注射地西泮和戊巴比妥钠的方法,探讨复合麻醉对小鼠的麻醉效果。方法将ICR小鼠随机分为对照组和试验组。对照组小鼠皮下注射生理盐水(0.1mL/10g)和试验组小鼠皮下注射地西泮(1mg/kg)后,分别放入小鼠自主活动箱内,记录小鼠的自主活动次数。然后,两组小鼠均腹腔注射戊巴比妥钠(50mg/kg),记录小鼠翻正反射消失时间和翻正反射恢复时间。结果注射地西泮小鼠自主活动次数显著少于生理盐水组P〈0.01)。地西泮和戊巴比妥钠联合麻醉小鼠比戊巴比妥钠单独麻醉小鼠的入睡时间显著缩短P〈0.01),睡眠时间显著延长(P〈0.01)。结论地西泮和戊巴比妥钠联合麻醉明显提高小鼠的麻醉效果。  相似文献   

5.
研究金线莲甲醇提取物的降血糖作用及其机制.将正常小鼠和链尿佐菌素(STZ)诱导成功的糖尿病小鼠随机分成5组, 14 d后,分别测定小鼠的肝糖原、血糖、血脂及血清抗氧化指标.结果表明,金线莲甲醇提取物能显著降低糖尿病小鼠的血糖,使小鼠血清中超氧化物歧化酶(SOD)活性升高,丙二醛(MDA)浓度显著下降;能显著降低糖尿病小鼠血清中甘油三酯(TG)、总胆固醇(TC)的浓度,并使小鼠的肝糖原质量比显著增加.金线莲甲醇提取物有降血糖作用,其降糖机制可能与其调节血脂水平、增加外周组织对葡萄糖的利用及提高糖尿病小鼠的抗氧化能力有关.  相似文献   

6.
就环磷酰胺抑制小鼠血清溶血素的生成是否存在性别差异进行了讨论,并就环磷酰胺对小鼠脾/体重的影响进行了探讨.结果表明,虽然环磷酰胺对小鼠血清溶血素的产生具有显著的抑制作用,但这种抑制作用没有性别差异,并且对小鼠脾/体重也没有显著影响.  相似文献   

7.
就环磷酰胺抑制小鼠血清溶血素的生成是否存在性别差异进行了讨论,并就环磷酰胺对小鼠脾/体重的影响进行了探讨.结果表明,虽然环磷酰胺对小鼠血清溶血素的产生具有显著的抑制作用,但这种抑制作用没有性别差异,并且对小鼠脾/体重也没有显著影响.  相似文献   

8.
以C57BL/6J雄性小鼠为试验对象,利用抵抗素重组蛋白进行尾静脉注射,模拟高循环水平抵抗素状态,探讨抵抗素对雄性小鼠生殖功能的影响.10只8周龄无特定病原体(SPF)级C57BL/6J雄性小鼠随机分为试验组和对照组,试验组小鼠注射抵抗素400 ng/(d·只),对照组小鼠注射等量的双蒸水.7 d后测定小鼠血清生殖激素水平的变化,检查精子的活动能力以及睾丸组织结构和形态变化.研究结果发现:试验组小鼠的血清雌二醇(E2)质量浓度和睾酮(T)质量浓度均显著高于对照组小鼠(P<0.05),促卵泡成熟素(FSH)质量浓度和促黄体生成素(LH)质量浓度与对照组差异不显著(P>0.05).试验组小鼠精子活力显著下降,精子形态异常现象显著增加.试验组小鼠曲精小管直径小于对照组,管腔相对较大,睾丸出现超微结构病变.抵抗素能够引起小鼠血清性激素水平变化,导致小鼠生殖功能下降.  相似文献   

9.
目的测定C57小鼠与MRL/lpr转基因小鼠在4月龄、5月龄和6月龄的血常规值和脏器系数。方法用MEK-7222K全自动血液分析仪检测C57小鼠与MRL/lpr转基因小鼠血常规值。结果血常规检测方面,C57小鼠与MRL/lpr转基因小鼠相比,中性粒细胞百分率(NE%)、红细胞计数(RBC)、红细胞压积(HCT)、红细胞平均血红蛋白(MCH)、红细胞平均血红蛋白浓度(MCHC)在不同月龄的数值差异极显著(P0.01);其中9个检测比较项目差异不显著(P0.05)。脏器系数方面,C57小鼠的心脏系数、肾脏系数显著高于同月龄的MRL/lpr转基因小鼠(P0.01);MRL/lpr转基因小鼠的肝脏系数显著高于同月龄的C57小鼠(P0.01);其他比较项目差异不显著(P0.05)。结论 C57小鼠与MRL/lpr转基因小鼠在同月龄的部分血常规数据和脏器系数差异显著。  相似文献   

10.
通过建立长期递增负荷训练、力竭训练游泳运动模型,探讨牡蛎提取液对长期训练小鼠运动耐力、血液生化指标影响.研究表明:运动训练的小鼠比安静状态下的小鼠血红蛋白水平显著降低,血中乳酸、肌酸激酶和尿素氮的水平显著升高;而补充牡蛎提取液可使运动训练小鼠血红蛋白的水平显著升高,血中乳酸、肌酸激酶和尿素氮的水平显著下降,并可使小鼠力竭运动时间明显延长.因此,牡蛎提取液可提高机体的造血功能和循环系统功能,增强机体的运动能力.  相似文献   

11.
Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.  相似文献   

12.
何延凌 《科技信息》2008,(4):258-258
Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women's language from these perspectives: pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women's language, more attention should be paid to language use in social context. What's more, the linguistic phenomena in a speaking community can be understood more thoroughly.  相似文献   

13.
There are numerous geometric objects stored in the spatial databases. An importance function in a spatial database is that users can browse the geometric objects as a map efficiently. Thus the spatial database should display the geometric objects users concern about swiftly onto the display window. This process includes two operations:retrieve data from database and then draw them onto screen. Accordingly, to improve the efficiency, we should try to reduce time of both retrieving object and displaying them. The former can be achieved with the aid of spatial index such as R-tree, the latter require to simplify the objects. Simplification means that objects are shown with sufficient but not with unnecessary detail which depend on the scale of browse. So the major problem is how to retrieve data at different detail level efficiently. This paper introduces the implementation of a multi-scale index in the spatial database SISP (Spatial Information Shared Platform) which is generalized from R-tree. The difference between the generalization and the R-tree lies on two facets: One is that every node and geometric object in the generalization is assigned with a importance value which denote the importance of them, and every vertex in the objects are assigned with a importance value,too. The importance value can be use to decide which data should be retrieve from disk in a query. The other difference is that geometric objects in the generalization are divided into one or more sub-blocks, and vertexes are total ordered by their importance value. With the help of the generalized R-tree, one can easily retrieve data at different detail levels.Some experiments are performed on real-life data to evaluate the performance of solutions that separately use normal spatial index and multi-scale spatial index. The results show that the solution using multi-scale index in SISP is satisfying.  相似文献   

14.
王慧 《科技信息》2008,(10):240-240
Wuthering Heights, Emily Bronte's only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.  相似文献   

15.
The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.  相似文献   

16.
The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3~4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰~ -7.8‰, PDB) and matrix dolomites (-6.6‰~ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084~0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078~0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.  相似文献   

17.
In the 19th century the society was controlled by men, and women were just appendants of them, they had not any rights and freedom. But Jane was an exception, she showed some characteristics of early feminist. Jane showed her characteristics of feminism in three aspects: rebellion, equality, and independence. These characteristics were helpful to her success, and feminism is the only way out for women of that time.  相似文献   

18.
理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。  相似文献   

19.
As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.  相似文献   

20.
1 Rise of studies on climate change's effects on biodiversity
Until the 1980s, climate change and biodiversity were studied as two independent disciplines for more than a century. In 1992, the Ecological Society of America's annual report named climate change, biodiversity, and the sustainable ecological system as the three major global environmental issues of the twenty-first century [1].  相似文献   

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