超声激活血卟啉杀伤癌细胞的扫描电镜观察

利用频率为2MHz,强度为0．9W／cm^2的超声(Ultrasound,US)激活血卟啉(Hematoporphyrin deriVatives,HpD)对在体的腹水型艾氏腹水瘤细胞(Ehrlich Ascites Tumor,EAT)和S180(Sarcomal80,S180)细胞进行抑癌作用研究。通过扫描电子显微镜观察处理后细胞形态的变化,结果表明：超声激活血卟琳对艾氏腹水瘤细胞和S180细胞均有明显的杀伤效果,且通过对损伤不同形态的比较,得出S180细胞膜较艾氏腹水瘤细胞膜对于声动力疗法(Sonodynamic Therapy,SDT)更为敏感。     

基于波动理论消除表层多次波

基于波动理论和Berkhout的反馈模型,可通过反馈回路的物理系统产生包括多次波的地震记录,并可表示为一组第二类积分方程。首先通过原始记录与一次波的初始估计值(可以是炮记录本身)的空间褶积预测多次波,再用最小能量准则反演求得的表层算子的逆来标定多次波,最后从原始记录中将多次波消除。整个预测过程无须知道宏观速度场,增强了预测方法的适应性。为更好地消除表层多次波,应采用迭代反演的方法。理论模型试算和实际资料试处理的结果表明,该方法对表层多次波有较好的压制作用,一般只需2～3次迭代即可。其处理效果要优于拉冬变换法,对100炮左右的常规数据来说,一次迭代一般需要30min左右。     

基于波动理论消除表层多次波

基于波动理论和Perkhout的反馈模型,可通过反馈回路的物理系统产生包括多次波的地震记录,并可表示为一组第二类积分方程。首先通过原始记录与一次波的初始估计值(可以是炮记录本身)的空间褶积预测多次波,再用最小能量准则反演求得的表层算子的逆来标定多次波,最后从原始记录中将多次波消除。整个预测过程无须知道宏观速度场,增强了预测方法的适应性。为更好地消除表层多次波,应采用迭代反演的方法。理论模型试算和实际资料试处理的结果表明,该方法对表层多次波有较好的压制作用,一般只需2～3次迭代即可。其处理效果要优于拉冬变换法,对100炮左右的常规数据来说,一次迭代一般需要30min左右。     

渗碳钢等温淬火多次冲击抗力的试验研究

本文试验研究证明:三种渗碳钢在渗碳一次再加热等温淬火处理后比通常渗碳一次再加热淬火回火处理具有更高的多次冲击弯曲抗力。当等温温度较低时,多次冲击侧向压缩抗力也较高。这就为进一步提高渗碳钢强度特性提供了一种新的强化工艺措施。试验分析指出:多次冲击抗力的这些变化规律是与载荷性质,金相组织(马氏体组织形态,马氏体与贝氏体相对量)及残余应力沿渗碳层分布密切相关的。     

红曲霉M1发酵糙米代谢产物抗S180细胞增殖效应研究

以红曲霉M1分别发酵大米和糙米,比较其代谢产物的变化;采用MTT比色法,初步研究了Monacolin K标准品、红曲糙米及红曲大米乙醇提取物对S180小鼠腹水瘤细胞的抑制作用. 结果表明：在MBR乙醇提取物中,可检测到MK的酸式构型,MK含量约为MR乙醇提取物的13倍. 经红曲霉M1发酵后,MBR中γ-氨基丁酸-GABA-质量浓度达到298mg/g,是MR乙醇提取物的31倍. MBR中桔霉素质量浓度低于MR. MK标准品、MBR及MR乙醇提取物均对S180小鼠腹水瘤细胞具有一定的抑制作用. MK质量浓度在3~50 μg/mL,三者抑制S180小鼠腹水瘤细胞增殖效应随MK质量浓度的增大而增大. 在MK含量相同的条件下,MR和MBR乙醇提取物的抑制效果显著大于MK标准品-P<001- .     

基于布尔向量运算的Apriori算法

关联规则挖掘是数据挖掘中的一个重要课题,常用的Apriori 算法要多次扫描数据库,会产生大量的候选项集.利用向量的内积运算和逻辑运算提出了一种关联规则挖掘的改进算法.研究表明,该算法运算简单,只需要扫描一次数据库,不需要产生候选项集,且具有处理大型数据库的优点.     

多次弹塑性撞击实验系统的设计与数值仿真

为了实验测量柔性撞击过程中的次撞击行为及其动力学响应,该文设计了一套多次弹塑性撞击实验系统.对该实验系统进行的三维动力有限元数值仿真结果表明,该系统可以激发出多次弹塑性撞击,有效地模拟几种典型构件之间的次撞击行为.采用数值仿真方法研究了测试梁材料、支承方式等对次撞击过程的影响,确定了满足实验要求的撞击力和梁位移测试性能指标.     

Android平台中无线定位的多次逆推模型

目的研究适用于资源受限的条件下的无线定位技术,建立基于Android终端的无线定位多次逆推模型,使系统具有较高的定位精度和较强的通用性.方法采用多次逆推模型进行多次定位,用终端的位移和方位角推导测试点位置坐标,综合多次定位结果推算测试点的位置坐标.结果在真实手机平台上实现了多次逆推模型,测试结果表明逆推次数为3~20次时,比常规一次定位精度提高20%~40%,验证了方案的可行性.结论采用多次逆推模型能够有效提高移动终端定位精度,同时没有增加移动终端的计算代价与资源消耗.     

层状介质模型的散射波场

运用逆散射序列方法能去除自由表面和内部多次波.通过研究正散射序列的性质,讨论了散射序列与一次波和多次波的关系,指出了用散射理论描述多次波和一次波的步骤和方法;此外,讨论了Bom近似与逆散射序列成像之间的差异.研究结果表明Bom近似成像法仅对于小扰动量适用,对于大扰动量,Bom近似值会产生较大的误差,而运用逆散射序列成像可以得到模型参数的精确值.     

超声激活血卟啉对在体艾氏腹水瘤杀伤效应的研究初报

利用超声激活血卟啉，研究对在体艾氏腹水瘤癌细胞的杀伤作用．实验分别选择不同的超声时间及取材时间．结果表明，单纯超声及血卟啉加超声组对肿瘤细胞均有杀伤作用．强度为0．9W／cm^2，声照3min，6h取材，为艾氏腹水瘤的杀伤效应最佳参数．     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

A computer generator for randomly layered structures

AcomputergeneratorforrandomlylayeredstructuresYUJia shun1,2,HEZhen hua2(1.TheInstituteofGeologicalandNuclearSciences,NewZealand;2.StateKeyLaboratoryofOilandGasReservoirGeologyandExploitation,ChengduUniversityofTechnology,China)Abstract:Analgorithmisintrod…     

海南岛地体及其毗邻陆缘晚中生代—新生代古地磁研究和构造演化

本文叙述了对海南岛及其毗邻大陆边缘白垩纪到第四纪地层岩石进行古地磁研究的全部工作过程。通过分析岩石中剩余磁矢量的磁偏角及磁倾角的变化,提出海南岛白垩纪以来经历的构造演化模式如下:早期伴随顺时针旋转而向南迁移,后期伴随逆时针转动并向北运移。联系该地区及邻区的地质、地球物理资料,对海南岛上述的构造地体运动提出以下认识:北部湾内早期有一拉张作用,主要是该作用使湾内地壳显著伸长减薄,形成北部湾盆地。从而导致了海南岛的早期构造运动,而海南岛后期的构造运动则主要是受南海海底扩张的影响。海南地体运动规律的阐明对于了解北部湾油气盆地的形成演化有重要的理论和实际意义。     

Exciton Seebeck in Molecular Systems

Various applications relevant to the exciton dynamics,such as the organic solar cell,the large-area organic light-emitting diodes and the thermoelectricity,are operating under temperature gradient.The potential abnormal behavior of the exicton dynamics driven by the temperature difference may affect the efficiency and performance of the corresponding devices.In the above situations,the exciton dynamics under temperature difference is mixed with     

Achieving Unusual States of Matter Under High Pressure

The elongation method,originally proposed by Imamura was further developed for many years in our group.As a method towards O(N)with high efficiency and high accuracy for any dimensional systems.This treatment designed for one-dimensional(ID)polymers is now available for three-dimensional(3D)systems,but geometry optimization is now possible only for 1D-systems.As an approach toward post-Hartree-Fock,it was also extended to     

《Chinese Science Bulletin》SUBJECT INDEX TO VOLUME 59(2014)

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An on-line scaling method for improving scalability of a database cluster

The explosive growth of the Internet and database applications has driven database to be more scalable and available, and able to support on-line scaling without interrupting service. To support more client's queries without downtime and degrading the response time, more nodes have to be scaled up while the database is running. This paper presents the overview of scalable and available database that satisfies the above characteristics. And we propose a novel on-line scaling method. Our method improves the existing on-line scaling method for fast response time and higher throughputs. Our proposed method reduces unnecessary network use, i.e. , we decrease the number of data copy by reusing the backup data. Also, our on-line scaling operation can be processed parallel by selecting adequate nodes as new node. Our performance study shows that our method results in significant reduction in data copy time.     

An improved R-tree based on childnode''s probability

R-Tree is a good structure for spatial searching. But in this indexing structure,either the sequence of nodes in the same level or sequence of traveling these nodes when queries are made is random. Since the possibility that the object appears in different MBR which have the same parents node is different, if we make the subnode who has the most possibility be traveled first, the time cost will be decreased in most of the cases. In some case, the possibility of a point belong to a rectangle will shows direct proportion with the size of the rectangle. But this conclusion is based on an assumption that the objects are symmetrically distributing in the area and this assumption is not always coming into existence. Now we found a more direct parameter to scale the possibility and made a little change on the structure of R-tree, to increase the possibility of founding the satisfying answer in the front sub trees. We names this structure probability based arranged R-tree (PBAR-tree).     

Integrating GIS Web services based on mediating architecture

The geographic information service is enabled by the advancements in general Web service technology and the focused efforts of the OGC in defining XML-based Web GIS service. Based on these models, this paper addresses the issue of services chaining,the process of combining or pipelining results from several interoperable GIS Web Services to create a customized solution. This paper presents a mediated chaining architecture in which a specific service takes responsibility for performing the process that describes a service chain. We designed the Spatial Information Process Language (SIPL) for dynamic modeling and describing the service chain, also a prototype of the Spatial Information Process Execution Engine (SIPEE) is implemented for executing processes written in SIPL. Discussion of measures to improve the functionality and performance of such system will be included.     

Tracking data management using topology of moving object database system for moving object constrained trajectory in LBS application

Advances in wireless technologies and positioning technologies and spread of wireless devices, an interest in LBS (Location Based Service) is arising. To provide location based service, tracking data should have been stored in moving object database management system (called MODBMS) with proper policies and managed efficiently. So the methods which acquire the location information at regular time intervals then, store and manage have been studied. In this paper, we suggest tracking data management techniques using topology that is corresponding to the moving path of moving object. In our techniques, we update the MODBMS when moving object arrived at a street intersection or a curved road which is represented as the node in topology and predict the location at past and future with attribute of topology and linear function. In this technique, location data that are corresponding to the node in topology are stored, thus reduce the number of update and amount of data. Also in case predicting the location,because topology are used as well as existing location information, accuracy for prediction is increased than applying linear function or spline function.