药食两用植物降血脂功能研究进展

对药食两用中药中降血脂功能性成分进行了综述，特别是对目前广泛存在于植物界的黄酮类化合物从其多种生物学作用、提取方法及应用进行了阐述，为该功能性成分的开发利用提供了参考，并说明黄酮类化合物是一类来源广泛，毒副作用少，具多种用途的天然植物成分。     

贝类免疫学研究新进展

综述了贝类免疫在细胞学和分子生物学研究方面取得的新进展．阐述了贝类血细胞中与免疫有关的结构和功能、血细胞的培养和凋亡；分别介绍了抗菌肽、蛋白酶抑制剂、类免疫球蛋白等贝类免疫应答因子的作用；论述了与免疫功能有关的基因研究．包括免疫基因的筛选、克隆和表达、基因的转移、重组和基因疫苗；初步探讨了贝类时免疫应答和免疫调节的分子生物学机理．为贝类的免疫生物学基础理论的研究提供资料．     

降血脂功能测定方法的研究进展

随着高血脂人群的增加,降血脂产品的研究与开发日益受到重视,如何快速准确地检测原料及产品的降血脂功能是降血脂产品开发及降血脂机理研究的重要前提。通过综合对比国内外常用的胆酸盐含量测定、脂肪酶活性测定等评价降血脂功能方法的应用及特点,以期为降血脂功能测定方法的深入研究及相关产品的开发提供参考。     

浅谈新型生态健康寝具对亚健康人群的作用

生态健康寝具集合多种生态能量因子，集中作用于亚健康人体．使人们在睡眠中不知不觉达到康复理疗的效果，从而使机体的功能恢复到健康状态、探计了生态能量因子对亚健康状态的治疗机理作用，给亚健康人群指出了一条新的、有效的治疗途径。     

植物线虫寄生策略及致病机理

植物寄生线虫与其寄主在漫长的进化过程中，已形成复杂的寄生关系，包括其取食的寄主细胞的形态和功能的改变．现代分子生物学技术的不断发展为我们在分子水平上阐述线虫致病机理提供了基础，致病机理作为线虫生物学防治的理论依据成为线虫学研究的焦点．阐述了植物寄生线虫寄生策略和致病机理方面的研究进展．     

双歧杆菌的营养保健功能

本文从微生态角度综合论述了双岐杆菌的生物屏障，营养、提高免疫力、抗肿瘤生理作用，并阐述了部分作用机理，提出了适量摄入含有双岐杆菌因子食物的建议。     

海事事故中人为失误的作用机理

针对目前在海上安全管理中，强调对人为失误的控制和预防，要求安全管理人员深入了解人为失误在事故中的作用机理，掌握预防人为失误的有关知识这一趋势．在亚当斯的事故因果连锁模型的基础上，分析了事故中人为失误不同的表现形式、作用机理、产生的原因和其影响因素，阐述了预防人为失误的主要原则和方法．安全理论的应用，将有利于进一步减少海事的发生，增进海上安全．     

乙烯、自由基、G_a~(2 )影响花的衰老的研究进展

本文根据前人关于花衰老的研究，阐述了乙烯、自由基和Ｇ２＋ａ对花的衰老的影响及作用机理，指出花的衰老是内部衰老因子相互作用的动态平衡被破坏的结果，乙烯可能是衰老因子之间相互作用的联系者。     

毛木耳多糖的研究进展

毛木耳是一种食药兼用的蕈菌,含有多种营养成分和活性物质,本文阐述了毛木耳多糖的提取工艺、多糖成分分析、凝血作用、降血脂功能和抗衰老等多种药理作用,为其开发利用奠定了基础.     

乙烯,自由基,G^2＋a影响花的衰老的研究进展

本文根据前人关于花衰老的研究，阐述了乙烯，自由基和Ｇ＾２＋ａ对花的衰老的影响及作用机理，指出花的衰老是内部衰老因子相互作用的动态平衡被破坏的结果，乙烯可能是衰老因子之间相互作的联系者。     

基于解释结构模型的血荒影响因素研究

针对我国众多城市医疗机构临床用血紧张、血荒现象日趋严重的现状,提出了血荒影响因素及其体系结构的研究问题;基于解释结构模型(ISM),建立具有一定逻辑关系的影响因子递阶有向图,分析出各因素对血荒影响程度;结果表明:血荒影响因素分为6个层次、4个层级,分别为浅层、中层、深层以及最深层,而献血率低及其驱动因素是导致血荒出现的主要因素,献血率低受到一系列深层和最深层因素的影响;从根本上解决血荒困境,重点在于提高无偿献血率,这需要建立一系列的献血招募长效机制,营造更加公平、完备、顺畅、透明的血液保障体系与社会环境。     

The search for new cardiovascular biomarkers

Despite considerable advances in the treatment of cardiovascular disease, it remains the leading cause of death in developed countries. Assessment of classic cardiovascular risk factors--including high blood pressure, diabetes and smoking--has a central role in disease prevention. However, many individuals with coronary heart disease (a narrowing of the blood vessels that supply the heart) have only one, or none, of the classic risk factors. Thus, new biomarkers are needed to augment the information obtained from traditional indicators and to illuminate disease mechanisms.     

松果粉末对废水中Cr（Ⅵ）的吸附特性研究

采用松果粉末作为吸附剂，进行了模拟含铬废水中Cr（Ⅵ）吸附试验研究，考察了不同吸附条件（吸附剂投加量、初始溶液pH值、Cr（Ⅵ）初始浓度、温度）对Cr（Ⅵ）去除效果的影响，并用红外光谱分析了吸附机理．结果表明：温度越高、pH值越低、投加量越大、Cr（Ⅵ）初始浓度越低越有利于Cr（Ⅵ）的去除．红外光谱分析表明，与Cr相互作用的基团主要是氨基、羟基、羧基和硫酸基．     

Functional localization and lateralization of human olfactory cortex.

Anatomical and physiological investigations in monkeys indicate that olfaction is subserved by several cortical regions. But the areas implicated in the human olfactory system have not been definitively identified by functional criteria. Behavioural evidence has suggested that laterally specialized mechanisms for odour processing may exist, but the neuroanatomical substrate remains unknown. We used positron emission tomography to study the cortical representation of human olfactory processing by comparing cerebral blood flow changes evoked during olfactory stimulation with those of a control task. We report here significant cerebral blood flow increases at the junction of the inferior frontal and temporal lobes bilaterally, corresponding to the piriform cortex, and unilaterally, in the right orbitofrontal cortex. The results complement and extend previous data implicating these regions in olfactory processing, and indicate that a functional asymmetry exists in the human brain favouring the right orbitofrontal area in olfaction.     

细胞周期调控的分子机制与关卡调控

通过对真核生物细胞增殖过程中细胞周期调控的分析, 归纳综合了以cyclin-CDK复合物为核心的细胞周期调控分子机制和以CKI、ATM、p53、Rb等为作用因子的关卡调控.此外, 外源性信号也对真核生物细胞周期起间接调控作用.     

芜湖河道浮游植物功能群分布及其与环境因子的关系

为研究城市河道浮游植物功能群组成及分布特征、环境因子对功能群的影响,鉴定芜湖三条城市河道中浮游植物种类并划分了功能群,分析浮游植物功能群分布特征,利用冗余分析研究环境因子与功能群间的关系。结果表明,研究区共鉴定出浮游植物47种,隶属6门32属,以硅藻、绿藻为主。研究区浮游植物可划分出C、P、MP、W2、E、X1、W1、X2等8种代表性功能群,三条河道代表性功能群分布呈现明显差异,中央城河道、汇成河道、中山南路河道主要代表性功能群分别是C+P+MP+E、C+X1、W1+E+X1+C,适应一定富营养化、有机质充足水体环境的功能群出现在各河道,表征了芜湖三条河道呈现不同程度的富营养化。溶解氧、总磷、总氮、氨氮是影响浮游植物功能群分布的主要环境因子。研究表明,芜湖各河道主要代表性功能群与氮、磷呈正相关,控制氮、磷外源输入并降低水体氮、磷含量对控制河道富营养化具有关键作用。     

Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries

Many tissues including blood, skin, gut and germ cells are continuously maintained by tissue stem cells. Under certain conditions, however, other organs can undergo repair using stem-cell-like progenitors generated by cell de-differentiation. Cell fates have been broadened experimentally, but mechanisms allowing de-differentiation to a stem cell state are poorly known. Germline stem cells begin to differentiate by forming interconnected germ cell cysts (cystocytes), and under certain conditions male mouse cystocytes have been postulated to revert into functional progenitors. Here we report that four- and eight-cell Drosophila germline cystocytes generated either in second instar larval ovaries or in adults over-producing the BMP4-like stem cell signal Decapentaplegic efficiently convert into single stem-like cells. These de-differentiated cells can develop into functional germline stem cells and support normal fertility. Our results show that cystocytes represent a relatively abundant source of regenerative precursors that might help replenish germ cells after depletion by genotoxic chemicals, radiation or normal ageing. More generally, Drosophila cystocytes now provide a system for studying de-differentiation and its potential as a source of functional stem cells.     

Visualizing columnar architectures using high-field fMRI

Among the many neuroimaging tools available for studying human brain functions, functional magnetic resonance imaging (fMRI) is the most widely used today. One advantage of fMRI over other imaging techniques is its relatively high spatial resolution. High-resolution fMRI, with its superb signal-to-noise ratio and improved tissue-vessel specificity, has strengthened the capability of fMRI and allowed mapping of fine cortical architectures in the human brain. In this review, I will first explain the factors limiting the spatial specificity of the blood oxygenation level-dependent (BOLD) effect, based on which most of fMRI experiments are conducted, and the measures dealing with these factors, and then briefly introduce several high-resolution (sub-millimeter) studies on the functional organization of human primary visual cortex (V1), including mapping of ocular dominance columns, mapping of temporal frequency dependent domains and direct demonstration of tuning to stimulus orientation.     

Vascular-specific growth factors and blood vessel formation

A recent explosion in newly discovered vascular growth factors has coincided with exploitation of powerful new genetic approaches for studying vascular development. An emerging rule is that all of these factors must be used in perfect harmony to form functional vessels. These new findings also demand re-evaluation of therapeutic efforts aimed at regulating blood vessel growth in ischaemia, cancer and other pathological settings.     

2型糖尿病患病因素对血糖影响的定量分析

为了解血糖变化特点和确定2型糖尿病干预靶点,提出了一种基于反向传播（BP）神经网络的患病因素对血糖影响的量化分析方法. 筛选出性别、体重等10维因素,再根据性别和年龄将人群分成9组,分别训练BP模型并提取敏感度,得出因素对血糖影响的量化值. 实验结果表明,体重对血糖变化的敏感度最大（0.244 9）,体重、血脂水平和年龄敏感度各占总量的25%、35%和17%,且不同性别、年龄敏感度排序不同,为个体细化干预提供了判定方法;该方法可推广到其它疾病危险因素的量化分析,还可用于因素干预-判定-因素干预的良性循环中,有效提升个体健康水平.