食道支架治疗晚期食道癌性狭窄8例

目的:探讨被膜食管内支架置入及姑息性治疗的临床效果.方法:8例高龄、晚期食道癌性狭窄患者,一次性直接置入网状被膜支架8枚.结果:8例均一次置入成功,随访2个月至20个月,患者吞咽正常.结论:食道支架治疗晚期食道癌性狭窄安全、有效,能迅速解除患者吞咽困难,提高生活质量.     

125Ⅰ粒子支架对食管癌放疗后病情进展患者治疗的临床研究

目的:对食管癌放射治疗后病情进展导致进食梗阻症状患者,应用125Ⅰ粒子支架植入进行治疗,并对其进行临床观察,以期找到对放射治疗后病情进展的食管癌患者的有效治疗方法.方法:在透视下对食管癌放射治疗后病情进展导致进食梗阻患者,经口置入捆绑式125Ⅰ粒子覆膜支架.术后按Stooler计分评价患者吞咽困难缓解程度,Karnofsky评分进行生活质量评价.定期随访进行食管造影,胸部CT检查,评价食管通畅率,各类并发症的发生率,患者生存时间统计.结果19例食管癌放射治疗后病情进展患者125Ⅰ粒子支架植入成功率100％,术后即刻吞咽困难缓解率100％,发生上消化道出血2例,术后再狭窄3例,纵隔内感染1例,并发症发生率为31.58％(6/19).置入术后生存期2～16个月,平均生存时间11个月.结论125Ⅰ粒子支架植入可有效改善放射治疗后病情进展导致进食梗阻患者的吞咽困难症状,改善其生活质量,延长患者生存时间,是一种新的安全、有效的治疗方法.     

高龄食管癌贲门癌的外科治疗

目的: 总结高龄食管癌贲门癌外科治疗经验. 方法:高龄食癌贲门癌 12 例, 均合并进行性营养不良和心血管、呼吸系统疾病.肿瘤切除+ 胃食管吻合 10 例(包括根治术和姑息手术) , 探查造瘘 2例. 结果: 全组无手术死亡,手术切除率83.33%, 3 例出现术后并发症,基本接近文献大宗病例报告.行切除术后病例随访均获得满意生存质量. 结论: 高龄食管癌、贲门癌患者应得到积极的手术治疗,高龄不是手术禁忌症.高龄患者围手术期处理至关重要,尤其是呼吸系统和营养不良,应在术前得到积极治疗和改善,术后加强呼吸道管理和有效的营养支持,可减少术后并发症.对于高龄食管癌、 贲门癌手术治疗的评价,不仅要重视术后生存率, 更应重视术后的生存质量.     

争光霉素A_5治疗原发性肝癌50例临床观察报告

原发性肝癌是恶性度较高,起病较隐蔽,病程较短,发展较快,死亡率较高的恶性肿瘤之一.发病后平均生存期为2.2～5.8月,目前国内用中草药、化疗、放射、手术等疗法,疗效如下:中草药、化疗一年生存率为5.4～14.0%;放射+综合治疗一年生存率19%;肝叶或半肝切除手术一年生存率可达28.3～60.8%,(普查组病例可达86.7%),二年生存率22.3～45%(普查组病例75%),三年生存率15.54～33.3%(普查组病例57.1%),五年生存率19%;手术效果较为满意.但国内手术切除率仅7.0～22.4%.手术死亡率尚有5.3～25.3%.而且限于技术,设备、病人经济等条件,不易在农村、工矿开展.为此,进一步寻     

经内窥镜逆行置留双J管的临床应用

目的:探讨经内窥镜置入双J管在上尿路梗阻性疾病中的应用价值.方法:对32例各种原因引起的不同程度上尿路梗阻性疾病患者,通过内窥镜置入双J管进行疗效观察和安全性能分析.结果:32例置管均顺利、管位正常,25例出现轻度膀胱刺激症或血尿,其余无明显不良反应.2例体外碎石患者缩短了排石时间,减少了并发症;4例术后漏尿患者置管后漏尿随即终止;肾功能不全组病例肾功能得到了改善,有利于二期手术;晚期癌肿压迫输尿管病例,除有效防止狭窄外,肾功能得到了进一步恢复,提高了生存质量.结论:双J管具有内引流和内支架的双重作用.经内窥镜置入双J管,具有操作简便、安全有效、并发症少等优点,是治疗上尿路梗阻性疾病的首选引流方式.     

胃镜引导下记忆覆膜金属支架置入在晚期食管癌治疗中的应用

目的：探讨经胃镜引导下带膜金属支架置入术在晚期食管癌治疗中的临床疗效。方法：收集2007年5月～2010年5月间入住我院的食管癌患者104例的临床资料,进行回顾性分析,观察治疗前后患者的食管扩张效果、吞咽困难改善情况、并发症的发生率及生存质量状态。结果：本组104例病例在胃镜下置入带膜金属支架,一次性操作成功率为100%,治疗后狭窄段直径及吞咽困难人数比例明显降低,差异具有统计学意义（P〈0.05）。术后主要的并发症有胸骨后疼痛或不适及反流性食管炎,也有部分患者出现黑便,仅一例出现食管穿孔,没有观察到其它严重并发症的发生。与对照组比较,经治疗后3个月和6个月患者生存率较高。结论：胃镜引导下置入带膜金属支架能够消除X线辐射伤害,具有定位准确,成功率高等优点,是延长食管癌患者生命,改善患者生活质量的一种有效方法,特别适合晚期食管癌患者。     

丹参多酚酸盐对冠状动脉内支架置入术后患者血清脂联素与抵抗素的影响

目的：研究丹参多酚酸盐对冠状动脉内支架置入后患者血清脂联素与抵抗素的影响.方法：将70例行冠状动脉内支架置入术的患者随机分为治疗组和对照组.对照组采用常规治疗方法进行治疗,治疗组在常规治疗基础上加用丹参多酚酸盐治疗,观察支架置入前、支架置入后24h及7d血清血清脂联素与抵抗素水平的变化.结果：治疗前两组患者血清脂联素与抵抗素水平无显著差异（P〉0.05）;两组患者血清脂联素水平于术后24h、术后7d均呈明显升高趋势（P＜0.05）;治疗组清脂联素水平于术后24h、术后7d均明显高于对照组（P＜0.05）.两组患者血清抵抗素水平于术后24h、术后7d均呈明显减低趋势（P＜0.05）;治疗组血清抵抗素水平于术后24h、术后7d均明显低于对照组（P＜0.05）.结论：丹参多酚酸盐可能通过降低抵抗素、升高脂联素发挥其抗炎、抗动脉粥样硬化作用,对冠脉内支架置入后患者发挥心血管保护作用.     

放射性粒子Ⅰ125植入治疗颅内恶性肿瘤 --附13例临床报告

目的:放射性粒子Ⅰ125植入治疗颅内恶性肿瘤的临床研究。方法:通过CT、放射、彩超引导下,或术中将粒子Ⅰ125植瘤体内,瘤床周围经Ⅰ125放射,对肿瘤直接照射,达到杀死瘤细胞,防止扩散,再发。结果:①转移性脑瘤治疗的无复发,②复发性脑膜瘤术后在瘤床植入一年无再发,③恶性脑瘤3mo瘤体开始缩小。结论:放射性粒子植入治疗颅内恶性肿瘤,对其物理、生物学特性,特别是临床剂量学与疗效,并发症的关系研究,恶性肿瘤是威胁人类健康的主要疾病。目前治疗的三大手段:手术切除,放射治疗和化学治疗,根据国际抗癌联盟(UICC)统计,肿瘤患者约70%需要通过放射达到根治或姑息治疗,或配合手术前、术后和术中进行放疗。放疗分体外放疗和近距离放疗(包括内放疗),放射性粒子植入有严格的适应和禁忌症,可用于局部恶性肿瘤的治疗,粒子植入能在肿瘤内部产生高剂量,可以提高肿瘤局部控制率。     

基于中药外伤的放射性皮肤损伤中西医治疗比较研究

目的对比中西医疗法治疗放射性皮肤损伤的疗效,找出简便、经济、疗效满意的治疗方法。方法雌性Wistar大鼠30只,用Co60γ射线以40 Gy进行照射建立急性放射性皮炎动物模型,分为中药方组、庆大霉素联合康复新组、紫草油与氯霉素组及模型对照组,待动物出现急性放射性皮肤损伤后,分别予中药方和庆大霉素联合康复新及紫草油与氯霉素溶液涂抹皮损部位,观察各组皮肤损伤变化。结果同一放射剂量下,用药组溃疡愈合率高于模型组(P0.05),紫草油与氯霉素组溃疡愈合率高于庆大霉素联合康复新组(P0.05);庆大霉素联合康复新组愈合率高于中药方组(P0.05)     

1例食管下段Schatzki环患者的护理并文献回顾

食管下段Schatzki环是指食管下段鳞柱状上皮交界处或胃食管交界部近侧1~2cm处的黏膜或黏膜下薄环,可引起食管狭窄并导致吞咽困难、食物嵌顿和胸痛,症状严重者多可经内镜下治疗缓解。该文结合1例典型病例的诊治及文献回顾,提出在该病护理上应重视其长病程与其他食管疾病的鉴别,针对进软食后易发不适和大块食物易引起嵌顿的特点进行饮食指导,并总结了该病行内镜下球囊扩张治疗的术前术后护理及相关心理护理的要点。     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

An Index mechanism for multi-scale view in spatial databases

There are numerous geometric objects stored in the spatial databases. An importance function in a spatial database is that users can browse the geometric objects as a map efficiently. Thus the spatial database should display the geometric objects users concern about swiftly onto the display window. This process includes two operations:retrieve data from database and then draw them onto screen. Accordingly, to improve the efficiency, we should try to reduce time of both retrieving object and displaying them. The former can be achieved with the aid of spatial index such as R-tree, the latter require to simplify the objects. Simplification means that objects are shown with sufficient but not with unnecessary detail which depend on the scale of browse. So the major problem is how to retrieve data at different detail level efficiently. This paper introduces the implementation of a multi-scale index in the spatial database SISP (Spatial Information Shared Platform) which is generalized from R-tree. The difference between the generalization and the R-tree lies on two facets: One is that every node and geometric object in the generalization is assigned with a importance value which denote the importance of them, and every vertex in the objects are assigned with a importance value,too. The importance value can be use to decide which data should be retrieve from disk in a query. The other difference is that geometric objects in the generalization are divided into one or more sub-blocks, and vertexes are total ordered by their importance value. With the help of the generalized R-tree, one can easily retrieve data at different detail levels.Some experiments are performed on real-life data to evaluate the performance of solutions that separately use normal spatial index and multi-scale spatial index. The results show that the solution using multi-scale index in SISP is satisfying.     

A computer generator for randomly layered structures

AcomputergeneratorforrandomlylayeredstructuresYUJia shun1,2,HEZhen hua2(1.TheInstituteofGeologicalandNuclearSciences,NewZealand;2.StateKeyLaboratoryofOilandGasReservoirGeologyandExploitation,ChengduUniversityofTechnology,China)Abstract:Analgorithmisintrod…     

海南岛地体及其毗邻陆缘晚中生代—新生代古地磁研究和构造演化

本文叙述了对海南岛及其毗邻大陆边缘白垩纪到第四纪地层岩石进行古地磁研究的全部工作过程。通过分析岩石中剩余磁矢量的磁偏角及磁倾角的变化,提出海南岛白垩纪以来经历的构造演化模式如下:早期伴随顺时针旋转而向南迁移,后期伴随逆时针转动并向北运移。联系该地区及邻区的地质、地球物理资料,对海南岛上述的构造地体运动提出以下认识:北部湾内早期有一拉张作用,主要是该作用使湾内地壳显著伸长减薄,形成北部湾盆地。从而导致了海南岛的早期构造运动,而海南岛后期的构造运动则主要是受南海海底扩张的影响。海南地体运动规律的阐明对于了解北部湾油气盆地的形成演化有重要的理论和实际意义。     

Exciton Seebeck in Molecular Systems

Various applications relevant to the exciton dynamics,such as the organic solar cell,the large-area organic light-emitting diodes and the thermoelectricity,are operating under temperature gradient.The potential abnormal behavior of the exicton dynamics driven by the temperature difference may affect the efficiency and performance of the corresponding devices.In the above situations,the exciton dynamics under temperature difference is mixed with     

Achieving Unusual States of Matter Under High Pressure

The elongation method,originally proposed by Imamura was further developed for many years in our group.As a method towards O(N)with high efficiency and high accuracy for any dimensional systems.This treatment designed for one-dimensional(ID)polymers is now available for three-dimensional(3D)systems,but geometry optimization is now possible only for 1D-systems.As an approach toward post-Hartree-Fock,it was also extended to     

《Chinese Science Bulletin》SUBJECT INDEX TO VOLUME 59(2014)

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An on-line scaling method for improving scalability of a database cluster

The explosive growth of the Internet and database applications has driven database to be more scalable and available, and able to support on-line scaling without interrupting service. To support more client's queries without downtime and degrading the response time, more nodes have to be scaled up while the database is running. This paper presents the overview of scalable and available database that satisfies the above characteristics. And we propose a novel on-line scaling method. Our method improves the existing on-line scaling method for fast response time and higher throughputs. Our proposed method reduces unnecessary network use, i.e. , we decrease the number of data copy by reusing the backup data. Also, our on-line scaling operation can be processed parallel by selecting adequate nodes as new node. Our performance study shows that our method results in significant reduction in data copy time.     

An improved R-tree based on childnode''s probability

R-Tree is a good structure for spatial searching. But in this indexing structure,either the sequence of nodes in the same level or sequence of traveling these nodes when queries are made is random. Since the possibility that the object appears in different MBR which have the same parents node is different, if we make the subnode who has the most possibility be traveled first, the time cost will be decreased in most of the cases. In some case, the possibility of a point belong to a rectangle will shows direct proportion with the size of the rectangle. But this conclusion is based on an assumption that the objects are symmetrically distributing in the area and this assumption is not always coming into existence. Now we found a more direct parameter to scale the possibility and made a little change on the structure of R-tree, to increase the possibility of founding the satisfying answer in the front sub trees. We names this structure probability based arranged R-tree (PBAR-tree).     

Integrating GIS Web services based on mediating architecture

The geographic information service is enabled by the advancements in general Web service technology and the focused efforts of the OGC in defining XML-based Web GIS service. Based on these models, this paper addresses the issue of services chaining,the process of combining or pipelining results from several interoperable GIS Web Services to create a customized solution. This paper presents a mediated chaining architecture in which a specific service takes responsibility for performing the process that describes a service chain. We designed the Spatial Information Process Language (SIPL) for dynamic modeling and describing the service chain, also a prototype of the Spatial Information Process Execution Engine (SIPEE) is implemented for executing processes written in SIPL. Discussion of measures to improve the functionality and performance of such system will be included.