A long noncoding RNA controls human dendritic cells function

Under a research project supported by the National Natural Science Foundation of China （Grant Nos. 31390431 and 81230074） and the National Basic Research Program of China （Grant No. 2013CB530502）, Prof. Cao Xuetaoand his colleagues from the National I,aboratoryof Medical Immunology of the Institute of Immunology at the Second Military Medical University, Shanghai, published their research results entitled ＂The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation＂ in Science （2014, 311（6181）： 310 313）.     

Nanotwinned diamond with unprecedented hardness and stability

Supported by the National Natural Science Foundation of China （Grant Nos. 51121061. 51172197 and 51332OO5） and the Ministry of Science and Technology of China, Prof. Tian Yongjun＇s Group at the State Key Imhoratory of Metastable Materials Science and Technology, Yanshan University successfully synthesized the nanotwinned diamond （nt-diamond） with unprecedented hardness and stability, which was published in Nature （2014, 510（7504）： 250 -3）.     

Structural TET-mediated insight into 5mC oxidation

With the support by the National Natural Science Foundation of China （Grant Nos. 31270779 and 31030019） and National Basic Research Program of China （ Grant Nos. 2011CB965300 and 2009CB918600）, Prof. Xu Yanhui＇s laboratory at Fudan University Shanghai Cancer Center （FUSCC） and Institute of Biomedical Sciences （IBS）, Fudan University, reported the crystal structure of TET2-DNA complex, which was published in Cell （2013 , 155（7）： 1545 55）.     

Visual image processing through interplay between cortical areas

With the support by the National Natural Science Foundation of China （Grant Nos. 31125014 and 30970983） and the Ministry of Science and Technology of China （Grant Nos. 2014CB846101 and 2011CBA00405）, and in collaboration with the scientists from Drexel University and Rockefeller University （Supported by the 111 Project）, Prof. LiWu＇s research group at the State Key I.aboratory of Cognitive Neuroscience and I.earning, Beijing Normal University, revealed how different cortical areas work synergistically to parse complex visual images （Neuron, 2014, 82（3）- 682 694）.     

Thymine DNA glycosylase promotes Wnt/β-catenin signaling

With the support by the National Natural Science Foundation of China （Grant Nos. 31230044, 30930052 and 30900763） and the Ministry of Science and Technology of China （Grant No. 2010CB912100）, Prof. Li I.in＇s laboratory at the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, reported a novel function of thymine DNA glycosylase （TDG） as a coactivator in Wnt signaling through cooperating with CBP, which was published in Journal of Molecular Cell Biology （2014, 6： 231--239）.     

Genomic and molecular characterization of esophageal squamous cell carcinoma

Supported by the National Natural Science Foundation of China （Grant No. 81330052） and National High-Tech Rg.D Program of China （Grant Nos. 2012AA02A503 and 2012AAO2A209）, Prof. Wang Mingrong＇s group at the Cancer Institute/Hospital, Chinese Academy of Medical Sciences published their recenl study, entitled ＂Genomic and molecular characterization of esophageal squamous cell carcinoma＂ in Nature Genetics （ 2014, 46（5）. 467 473）.     

A hole-conductor-free,fully printable mesoscopic perovskite solar cell with high stability

With the support by the National Natural Science Foundation of China （Grant No. 61106056）, Prof. Han Hongwei＇s group at Wuhan National I.aboratory for Optoelectronics, Huazhong University of Science and Technology, reported a hole-conductor-free, fully printable mesoscopic perovskite solar cell with high stability, which was published in Science （2014, 345（6194）.. 295--298）.     

Evidence of van Hove singularities in ordered grain boundaries of graphene

With the support by the National Natural Science Foundation of China and National Basic Research Program of China, Prof. Hou Jianguo and Prof. Wang Bing＇s laboratory at Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, reported the existence of van Hove singularities in ordered grain boundaries in graphene, which was published in Physical Review Letters （2014, 112： 226802）.     

Orbital-selective spin texture and its manipulation in a topological insulator

<正>Supported by the National Natural Science Foundation of China and the Ministry of Science and Technology of China(Grant Nos.2011CB921703and 2013CB921700),a research group led by Prof.Zhou Xingjiang at the Institute of Physics,Chinese Academy of Sciences,reported the direct observation of the orbital-selective spin texture and its manipulation in a topological insulator,which was published in Nature     

MicroRNA-26a alleviates lung fibrosis by inhibiting epithelial-mesenchymal transition

With the support by the Science Fund for Creative Research Groups of the National Natural Science Foundation of China （Grant No. 81121003）, Prof. Yang Baofeng, member of Harbin Medical University and colleagues published their research findings in an article ＂Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis＂, which was published in （Jell Death Dis （2014, 5： e1238）.     

Characterization of lipid-rich aortic plaques by intravascular photoacoustic tomography

With the support by the National Natural Science Foundation of China （Grant Nos. 61361160414, 61331001 and 81127004） and the National Basic Research Program of China （Grant Nos. 2010CB732602 and 2011CB910402）. Pro{. Xing＇s laboratory at the Ministry of Education Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, reported the characterization of lipid- rich aortic plaques by intravascular photoacoustic tomography. Ex-vivo and in-vivo validation in a rabbit atherosclerosis model with histologic correlation, which was published in Journal of the American College of Cardiology （2014, 64（4）： 385--390）.     

A biomimetic membrane for the studies of electron transfer in biological system

Supported by the National Science Fund for Distinguished Young Scholars and the Major Research Plan of the National Natural Science Foundation of China, Prof. Long Yitao from the East China University of Science and Technology and his colleagues published their work entitled ＂Investigating electron-transfer processes using a bio- mimetic hybrid bilayer membrane system＂ in Nature Protocols （2013, 8（3） ： 439--450）.     

The focus research of monosodium L-glutamate in animal nutrition

Monosodium L-glutamate （MSG） is a flavor enhancer and was first found by Ikeda in 1908. Then, MSG was broadly used in the food industry to enhance umami taste, especially in Asian countries including China. However, researches on MSG were relatively drab, and most of which focused on its neurotoxicity. Over the past 3 years, the research team led by Prof. Yin Yulong from the Institute of Subtropical Agriculture （ISA）, Chinese Academy of Sciences, have contributed a great deal of knowledge to the understanding of MSG for swine nutrition and health, which has important practical values for feed industries worldwide.. Their research was supported by the National Natural Science Foundation of China （Grant Nos. 31330075 and 31110103909）.     

Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism

With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China, Prof. Luo Jie and his colleagues from the National Key Laboratory of Crop C-enetic Improvement, Huazhong Agricultural University, published their research findings in an article ＂Genomewide association analyses provide genetic and biochemical insights into natural variation in rice metabolism＂ in Nature Genetics （2014, 46（7）： 714-721）.     

Entanglement of three quantum memories via interference of three single photons

<正>With support by the National Key RD Program of China,Anhui Initiative in Quantum Information Technologies,National Natural Science Foundation of China,and Chinese Academy of Sciences,the research team led by Prof.Pan JianWei and Prof.Bao XiaoHui(包小辉)at the University of Science and Technology of China reports the generation and verification of entanglement of three remote quantum     

Discoveryof full flux-closure domains in ferroelectrics

<正>With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,a research team led by Prof.Ma Xiuliang,Prof.Zhu Yinlian and Dr.Tang Yunlong at the Institute of Metal Research,Chinese Academy of Sciences,reported an observation of a periodic array of flux-closure quadrants in strained ferroelectric PbTiO3films,which was published in Science(2015,     

Agonist-bound structure of the human P2Y12 receptor

With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China, Prof. Zhao Qiang and Prof. Wu Beili＇s laboratories at Shanghai Institute of Materia Medica, Chinese Academy of Sciences, reported the crystal structure of the human P2Y12 receptor bound to an agonist, which was published in Nature （2014, 509（7498）： 119--122）.     

Type-Ⅱ Ising pairing in few-layer stanene

正With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,the research team led by Associate Prof.Zhang Ding(张定)and Prof.Xue QiKun(薛其坤)at the Department of Physics,Tsinghua University,in collaboration with Prof.Liu HaiWen of Beijing Normal University,Prof.Jurgen Smet of Max Planck Institute for Solid State Research in     

Visualizing coherent intermolecular dipole-dipole coupling in real space

<正>With the support by the National Natural Science Foundation of China,the research team led by Prof.Dong Zhenchao(董振超)and Prof.Hou Jianguo from Hefei National Laboratory for Physical Sciences at the Microscale in the University of Science and Technology of China made new progress in imaging intermolecular dipole-dipole interactions.The related research paper entitled"Visualizing coherent intermolecu-     

New structural design of topological insulator:Spiral growth of two-dimensional layered material

<正>With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,Prof.Zeng Jie's laboratory at Hefei National Laboratory for Physical Sciences at the Microscale,University of Science and Technology of China,reported the new progress in the controlled