陇中骨刺膏治疗膝骨关节炎临床疗效研究

观察陇中骨刺膏治疗膝骨关节炎的临床疗效。选取2018年6月15日至2018年12月15日因膝骨关节炎就诊于甘肃中医药大学门诊患者90例,采用随机数字表法随机分为治疗组和对照组各45例。治疗组应用陇中骨刺膏治疗,对照组应用常规药物(双氯芬酸钠胶囊、盐酸氨基葡萄糖片)治疗,治疗时间均为4周。观察2组治疗前后临床疗效和WOMAC评分及Hass评分的变化。2组患者的临床症状均得到明显缓解,治疗组疗效优于对照组(P0.05);治疗后2组WOMAC评分及Hass评分较治疗前均明显降低,且治疗组各指标均优于对照组,差异有统计学意义(P0.05);治疗组胃肠道等副作用明显少于对照组(P0.01)。陇中骨刺膏治疗膝骨关节炎疗效显著。所有患者入组后,行常规膝关节专科检查,陇中骨刺膏组治疗方案:每2日/贴,隔日一贴,4周为1疗程,连续用药1疗程。口服药物组治疗方案:双氯芬酸钠胶囊(100mg),1粒/次,1次/日、盐酸氨基葡萄糖片(240mg/片),1片/次,3次/日;4周为1疗程,连续用药1疗程。两组均在治疗前、治疗后2周,4周进行膝关节视觉疼痛评分法(VAS)、Womac评分法、Hass评分法评价治疗效果。     

辨证施药火龙疗法干预早期膝骨关节炎疼痛的效果分析

目的:分析辨证施药火龙疗法干预早期膝骨关节炎的效果.方法:将160例早期膝骨关节炎患者按就诊顺序分为对照组和观察组,对照组按中医诊疗规范给予药物治疗、物理治疗、运动治疗、健康教育等,观察组在对照组基础上给予辨证施药火龙疗法治疗.以痛疼指数和临床疗效作为评价指标,观察两组患者效果.结果:疼痛干预效果:观察组治疗前疼痛评分5.55±0.16,治疗后1.39±0.088,治疗前后p≤0.05,差异具有统计学意义.对照组治疗前疼痛评分5.5±0.16,治疗后1.91±0.14,治疗前后p≤0.05,差异具有统计学意义.且治疗前观察组与对照组比较,p≥0.05,差异无统计学意义.而治疗后观察组与对照组比较,p≤0.05,差异具有统计学意义.临床治疗效果:治疗组治愈率、显效率、有效率、总有效率均高于对照组,而无效率小于对照组,2组比较p≤0.05,差异具有统计学意义.结论:辨证施药火龙疗法有助于患者早期膝骨关节炎患者疼痛症状改善,有助于提高整体治疗效果,促进患者康复.     

盐酸氨基葡萄糖联合透明质酸钠治疗膝骨性关节炎的效果探究

探究盐酸氨基葡萄糖联合透明质酸钠治疗膝骨性关节炎(knee osteoarthritis,KOA)的效果。将秦安县人民医院2018年6月～2019年5月收治的86例KOA按照随机数字表法划分成对照组(n=43例)和治疗组(n=43例),分别采取单一盐酸氨基葡萄糖治疗及其联合透明质酸钠治疗。比较两组临床疗效、膝关节功能及血清炎症因子水平。结果:治疗后,治疗组总有效率达90.70%,较对照组的72.09%高(P0.05);两组骨关节炎指数评分(WOMAC)及血清肿瘤坏死因子-α(TNF-α)、白细胞介素-1(IL-1)等炎症因子水平与治疗前相比均降低(P0.05),且上述指标治疗组均较对照组低(P0.05)。对KOA患者进行盐酸氨基葡萄糖联合透明质酸钠治疗,其疗效好于单一盐酸氨基葡萄糖治疗,可显著改善临床症状及膝关节功能,有效下调血清TNF-α、IL-1等炎症因子水平。     

兔膝骨关节炎模型的建立及评价

目的 通过兔软骨缺损制备兔膝骨关节炎模型并进行评价。方法 将动物按体质量和性别随机分成3组：假手术组,模型组和阳性对照氨基葡萄糖组,每组12只。造模4周后开始灌胃给药,每天1次,连续给药4周。末次给药后,将动物处死,ELISA试剂盒检测血清及关节液中IL-1β和TNF-α水平,对关节软骨和滑膜进行HE染色,并对关节软骨进行Mankin’s评分以评价其损伤情况。结果 与假手术组相比,模型组血清、关节液中IL-1β、TNF-α水平明显升高,而给予氨基葡萄糖可降低血清、关节液中IL-1β、TNF-α水平。HE染色见模型组软骨结构改变、缺损,滑膜有炎细胞浸润;软骨评分明显高于假手术组。给予氨基葡萄糖可以减轻软骨缺损,减少滑膜炎细胞浸润,降低软骨评分。结论 关节软骨钻孔可建立兔膝骨关节炎模型,反映其主要特征,并能通过给予阳性对照药减轻损伤和炎症反应。该模型可用于治疗关节炎药物的评价和筛选。     

独活寄生汤搭配玻璃酸钠治疗膝骨关节炎对其生活质量的影响

探讨独活寄生汤搭配玻璃酸钠治疗膝骨关节炎对其生活质量的影响。选取甘肃省武山县中医医院2014年6月至2015年12月收治的膝骨关节炎患者110例作为研究对象,随机分为观察组和对照组,各组55例。对照组给予玻璃酸钠治疗,观察组给予独活寄生汤搭配玻璃酸钠治疗。观察两组患者治疗效果、膝关节功能恢复情况及生活质量改善情况。观察组患者治疗有效率明显比对照组高(P0.05);治疗前两组患者膝关节功能及生活质量平均评分没有明显差异(P0.05);治疗后观察组患者膝关节功能及生活质量平均评分均显著高于对照组(P0.05)。膝骨关节炎采用独活寄生汤搭配玻璃酸钠治疗效果显著,有效的改善了患者膝关节功能及生活质量,值得应用及推广。     

自制肢体康复装置在脑卒中后偏瘫患者康复治疗中的疗效观察

探讨应用自制肢体康复装置包括上肢康复装置、下肢康复装置(实用新型发明专利:上肢康复装置,发明专利号:ZL201520279231.0;下肢康复装置,发明专利号:ZL201510040238.1)治疗7 d、14 d,治疗前后NIHSS评分变化、治疗14d后ADL量表评分变化、总有效率等。选择武威医学科学院神经内科2018年6月—2020年6月诊断为脑卒中后偏瘫患者84例,均有程度不同肢体功能障碍,肌力0～5级,其中脑梗死68例,脑出血16例。采用简单随机分为治疗组和对照组各42例,治疗组患者采用自制肢体康复装置康复治疗+常规治疗。对照组采用常规治疗。治疗组和对照组患者神经功能缺损评分(NIHSS),日常生活能力量表(ADL)、总有效率进行比较。两组患者神经功能缺损评分、日常生活能力改善、总有效率均有显著差异变化,治疗组改善明显优于对照组(P0.05)。自制肢体康复装置在脑卒中后偏瘫患者肢体功能恢复中疗效显著。     

量子血病治疗脑血栓106例疗效观察

本文报告了我院206例脑血栓患者,按全国第二次脑血管病学术会议通过的“脑卒中患者临床神经功能缺损程度评分标准”评分,随机分组,血疗组106例,对照组100例。对照组单用药物治疗:丹参、维脑路通、胞二磷胆碱、阿斯匹林及潘生丁。血疗组在用上述药物的同时,加用量子血疗,通过30天的治疗观察,分析统计结果,血疗组康复速度明显优于对照组。结论:脑血栓在药物治疗的同时,配合量子血疗,其作用是积极而有效的。     

膝痛洗方热敷结合推拿对膝骨关节炎疗效的观察

观察膝痛洗方热敷结合推拿对膝骨关节炎的疗效。选取甘肃省庆阳市西峰区人民医院2015年5月~2016年7月收治的膝骨关节炎患者76例,随机均分成观察组与对照组,各38例。对照组采取推拿配合温水热敷治疗,观察组在推拿的基础上实施膝痛洗方热敷治疗。对两组患者的临床疗效及疼痛、关节活动度、步行能力、日常生活能力进行比较。治疗2周后,观察组临床疗效优于对照组(P0.05);观察组患者疼痛、关节活动度、步行能力、日常生活能力评分均优于对照组(P0.05)。对膝骨关节炎患者临床应用膝痛洗方热敷结合推拿治疗,临床疗效显著,可有效改善其膝骨关节疼痛,促进其关节功能恢复。     

密集型银质针治疗膝骨性关节炎的临床疗效研究

研究密集型银质针疗法治疗膝关节骨性关节炎的疗效及特点。将260例KOA患者随机分成密集型银质针治疗组和玻璃酸钠关节腔注射对照组各130例,治疗组及对照组均每周治疗一次,2组连续治疗5周后评价治疗前后WOMAC骨关节炎指数动态结果和患者生存质量WHOQOL-BREF量表评分,并比较两组临床疗效。同时对两组病例进行不同影像学分级及疗效比较。治疗5周后进行两组治疗前后WOMAC骨关节炎指数和患者生存质量WHOQOL-BREF量表评分均较治疗前明显改善(P0.01,P0.01),治疗后2组组间比较:1WOMAC评分:差异有统计学意义(P0.01)2WHOQOL-BREF评分:在健康状况主观感觉,生理领域和心理领域方面,差异有统计学意义(分别P0.05,P0.01,P0.01)。对生存质量主观感觉、社会关系领域、环境领域的影响,两种疗法无差异(均P0.05)。治疗组总有效率为92.37%,对照组为77.69%(P0.05),治疗组疗效优于对照组。两组病例不同影像学分级及疗效比较结果显示治疗组对影像学分级较高的病例疗效更好。结论:密集型银质针治疗膝骨性关节炎具有良好的止痛效应与改善症状等作用,是治疗KOA值得推广的疗法之一。     

综合康复治疗脑卒中的临床观察

目的:观察综合康复治疗措施对脑卒中患者疗效的影响,探讨其可能的机制.方法:选择脑卒中患者78例,其中39例为康复组,采用神经内科常规药物治疗外,于病情稳定后1周,配合针刺、推拿、康复训练治疗.采用简式Fuql-Meyer(FMA)运动评分,改良的巴氏指数(BI)进行康复评定.结果:FMA、BI在治疗前两组患者比较差异无显著性意义(P>0.05),治疗后较治疗前改善明显,康复组较对照组改善明显(P<0.05).结论:药物治疗可使运动功能、ADL能力恢复、改善,但康复治疗能明显改善患肢运动功能和ADL,同时可缩短病程,减少致残率,优于单纯药物治疗.     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

Design and analysis of generic LBS application developing platform

Location based services is promising due to its novel working style and contents.A software platform is proposed to provide application programs of typical location based services and support new applications developing efficiently. The analysis shows that this scheme is easy implemented, low cost and adapt to all kinds of mobile nework system.     

橡胶颗粒沥青混合料低温抗裂性试验研究

以AC-13级配为基础,将橡胶颗粒代替部分集料掺入混合料中,以低温弯曲试验为评价方法对不同橡胶颗粒掺量下沥青混合料的低温抗裂性进行研究,并引入应变能密度值对混合料的低温抗裂性进行综合评价.试验结果表明:橡胶颗粒沥青混合料试件的破坏微应变均超过2 300,满足冬寒区的技术指标;无论是否掺加橡胶颗粒,随着温度的下降,沥青混合料破坏时的最大弯拉强度增大,弯拉应变降低,劲度模量增大;弯曲应变能密度在胶粒掺量为1%左右时具有较大的弯曲应变能密度值,此时橡胶颗粒沥青混合料具有较好的低温抗裂性.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

Quantitative trait loci （QTLs） for quality traits related to protein and starch in wheat

Quality traits in wheat （Triticum aestirum L.） were studied by quantitative trait locus （QTL） analysis in a recombinant inbred line （RIL） population, a set of 131 lines derived from Chuan 35050 × Shannong 483 cross （ChSh）. Grains from RILs were assayed for 21 quality traits related to protein and starch. A total of 35 putative QTLs for 19 traits with a single QTL explaining 7.99-40.52% of phenotypic variations were detected on 10 chromosomes, 1D, 2A, 2D, 3B, 3D, 5A, 6A, 6B, 6D, and 7B. The additive effects of 30 QTLs were positive, contributed by Chuan 35050, the remaining 5 QTLs were negative with the additive effect contributed by Shannong 483. For protein traits, 15 QTLs were obtained and most of them were located on chromosomes 1 D, 3B and 6D, while 20 QTLs for starch traits were detected and most of them were located on chromosomes 3D, 6B and 7B. Only 7 QTLs for protein and starch traits were co-located in three regions on chromosomes 1D, 2A and 2D. These protein and starch trait QTLs showed a distinct distribution pattern in certain regions and chromosomes. Twenty-two QTLs were clustered in 6 regions of 5 chromosomes. Two QTL clusters for protein traits were located on chromosomes 1D and 3B, respectively, three clusters for starch traits on chromosomes 3D, 6B and 7B, and one cluster including protein and starch traits on chromosome 1D.     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.