TS—1沸石合成过程中模板剂用量对钛进入骨架的影响

以ＴＰＡＢｒ为模板剂、ＮＨ３．Ｈ２Ｏ为碱源，水热条件下合成了ＴＳ－１沸石，采用ＸＲＤ、ＩＲ、ＵＶ－Ｖｉｓ、＾２９ＳｉＣＰＭＡＳＮＭＲ、＾２７ＡｌＣＭＡＳＮＭＲ、＾１３ＣＣＰＭＡＳＮＭＲ等表征手段详细研究了模板剂不同用量对钛进入骨架的影响。     

可聚合性季铵盐及其聚合物的合成与表征

合成了三种含不饱和双键和季铵盐：甲基丙烯酰氧乙基－苄基－二甲氯化铵（ＭＢ－ＤＡＣ）,甲基丙烯酰氧乙基－丁基－二甲基溴化铵（ＭＢＤＡＢ）和甲基丙烯酰氧乙基－乙基－二甲基溴化铵（ＭＥＤＡＢ）,用红外光谱,元素分析,核磁共振谱对其结构进行了表征。用自由基聚合法合成了ＭＢＤＡＣ的均聚物及其与甲基丙烯酸甲酯和苯乙烯的共聚物,并用元素分析、ＧＰＣ,红外光谱等表征了聚合物的结构,用ＤＳＣ和ＴＧ研究了其热稳定性,     

凝胶电解质LiClO4—PC—PMMA体系的离子导电性研究

研究了一种新型高子固态离子导体－凝胶电解质高氯酸锂－碳酸丙烯酯－聚甲基丙烯酸甲酯体系（ＬｉＣｌＯ４－ＰＣ－ＰＭＭＡ）离子电导性和电导机理，这类离子导体的电导率与温度的关系服从ＶＴＦ方程并与体系的ｗ（ＰＭＭＡ），玻璃化温度（Ｔｇ）碱金属盐的浓度（ｃ（ＬｉＣｌＯ４）等有关，当ｃ（ＬｉＣｌＯ４）＝０．５ｍｏｌ／Ｌ，ｗ（ＰＭＭＡ）＝３５％时，离子导体具有良好的粘附性，光学透明度及较高的室温离子电导率（δＲ     

壳聚糖─Cu（Ⅱ）配位聚合物的合成、表征及催化性能研究

采用一种新方法合成了壳聚糖与ＣＵ（Ⅱ）的配位聚合物，并用ＩＲ、ＥＳＲ、ＵＶ—ＶＩＳ、ＤＴＡ—ＴＧ和ＸＰＳ分析手段对配位聚合物进行表征．同时还研究了壳聚糖－ＣＵ（Ⅱ）配位聚合物与Ｎａ２ＳＯ３体系对ＭＭＡ聚合的催化性能，证实ＭＭＡ的聚合机理是按自由基机理进行的．     

环氧封端Cardo聚芳醚腈的研究

用凝胶渗透色谱仪（ＧＰＣ）在一定条件下，测定聚合物的分子量及其分布的变化可以预示聚合物的最佳合成条件。同时，用ＦＴ－ＩＲ和＾１ＨＮＭＲ表征了环氧封端酚酞型Ｃａｒｄｏ聚芳醚腈（Ｅ－ＴＭＰＣＥ）的分子链结构，测定了Ｅ－ＴＭＰＣＥ试样的环氧值和溶解性。     

录象脑电图与神经影像学检查对部分性癫痫定位诊断

利用灵象脑电图加强监测，９９ｍ＾ＴＣ－ＨＭＰＡＯ－ＳＰＥＣＴ，＾１２３Ｊ－Ｉｏｍａｚｅｎｉｌ－ＳＰＥＴ，ＭＲＩ对４０例局限性癫痫患者进行研究。分析发作期及发作间歇期Ｖｉｄｅｏ／ＥＥＧ的结果：３８例（８２％）表现局限性癫痫样活动ｍ，＾９９ｍＴＣ－ＨＭＰＡＯＳＰＥＣＴ局部脑血流异常２１例（５２％），＾１２３Ｊ－Ｉｏｍａｚｅｎｉｌ－ＳＰＥＣＴ局部脑苯二氮卓受体密度减低２５例（６３％），ＭＲＩ结构异常１８     

两种二乙酰二茂铁酰腙缩聚物的合成与表征

以１，１′－二乙酰二茂铁和酰肼为原料，合成两种未见报道的二乙二酰二藏铁酰腙缩聚物，并用ＵＶ、ＩＲ、ＴＧＡ及不同的Ｌｅｗｉｓ酸、高剂量γ－＾６０Ｃｏ辐照，研究了可溶与不可溶聚物的产率和性能的关系。     

聚[1,3—双（对羧基苯氧基）丙烷—癸二酸]的改进合成

采用溶缩缩聚法,在常压条件下,以二甲苯为溶剂、癸二酸和１,３－双（对羧基苯氧基）丙烷预聚物的单体,连续加热蒸馏二甲苯,得到高分子量的聚「１,３－双（对羧基苯氧基）丙烷－癸二酸」共聚物「Ｐ（ＣＰＰ－ＳＡ）」,合成产物分别用ＦＴ－ＩＲ,高分辨率＾１Ｈ－ＮＭＲ,ＧＰＣ,ＤＳＣ和ＴＧＡ等进行了表征。     

受阻胺光稳定剂的热失重分析

使用热失重分析仪对ＴＭＰ,ＰＭＰ,ＴＭＰＭ,ＧＷ５４０,Ｔｉｎｕｖｉｎ７７０等小分子型受阻胺光稳定剂、ＴＭＰＭ的均聚物ＰＴＭＰＭ和ＰＭＰＭ的均聚物ＰＰＭＰＭ、一系列具有不同单体配比的ＰＤＳ,ＴＭＰＭ和ＰＭＰＭ分别与ＭＭＡ,Ｓｔ,ＭＡＡ,ＡＡ共聚得到的共聚物等受阻胺类光稳定剂进行了热失重分析（ＴＧ）。实验发现小分子型的受阻胺光稳定剂的热稳定性均较差,它们的热稳定顺序是ＴＭＰ〈ＰＭＰ〈ＴＭＰＭ〈ＧＷ５     

D—氨基葡萄糖β—萘酚醛席夫碱及其Cu（Ⅱ）,Zn（Ⅱ）…

报导了Ｄ－氨基葡萄糖与β－萘酚醛形成的席夫碱（ＮＧ）及其铜（Ⅱ）「Ｃｕ（Ⅱ）ＮＧ」、锌（Ⅱ）「Ｚｎ（Ⅱ）ＮＧ」配合物的合成方法，通过元素分析、ＩＲ、ＵＶ－Ｖｉｓ、＾１ＨＮＭＲ、＾１３ＣＮＭＲ等手段对配体及配合物进行了表征，初步推配合物具有准四面体结构。     

富勒烯(C60/C70)-丙烯酸(酯)共聚物的合成及成膜性能研究

交纳米C60／C70与丙烯酸（酯）单体在引发剂作用共聚，合成得到C60／C70－丙烯酸（酯）共聚物，对该共聚物的结构进行了红外光谱分析，证实了C60／C70通过自由基聚合进入了聚合物碳链骨架，通过其成膜性能测试。C60／C70改性不仅使共聚物的成膜度有较大提高，同时也使其漆膜的柔韧性有相应的改进。     

菜籽油酸乙醇酰胺聚氧乙烯醚的合成及性能研究

以聚乙二醇(400)为原料，通过三步合成了菜籽油酸乙醇酰胺聚氧乙烯醚。首先按照菜籽油酸：乙醇胺(1t001)=1：0．75，催化剂KOH：菜籽油酸(mol)：0．076：1，0，温度为170℃，加入乙醇胺反应4h，再加入乙醇胺，使总的菜籽油酸：乙醇胺(mol)=1：1．0，在105℃反应3h得到菜籽油酸乙醇酰胺。然后，在碱性条件下，酰胺与环氧氯丙烷反应生成环醚。最后环醚与聚乙二醇(400)反应生成聚氧乙烯醚。正交试验确定较佳工艺条件为：环醚：聚乙二醇(mol)为1：1．2，反应时间3h，反应温度140℃产品收率达92％。通过红外光谱确定了产品的结构，并对产品的表面物性进行了分析。结果 表明产品具有较好的降低水表面张力的能力，并具有良好的增稠润湿性能。     

酯键溶血磷脂酸和醚键溶血磷脂酸的全合成

报导了酯键溶血磷脂酸和醚键溶血磷脂酸消旋体的合成。通过相同的中间体2－O－苄基甘油，它们分别经过6步反应被制得。这种方法可以用来制备溶血磷脂酸的半抗原，从而用于制备抗体。     

Sequencing of phosphopeptides sulfonated by 4-sulfophenyl isothiocyanate using post-source decay matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Phosphorylation/dephosphorylation is probably the most common and important reversible post-translational modification of proteins. Analyzing the functional effects of phosphorylation is helpful for understanding the biological functions of proteins. Identification of the phosphorylation sites of phosphorylated protein is a prerequisite for research on phosphorylation. In this work, an effective and simple method of identification of protein phosphorylation sites has been developed. Phosphopeptides were selectively enriched with immobilized metal affinity chromatography (IMAC) and subsequently chemically modified by 4-sulfophenyl isothiocyanate, and then the chemically modified phosphopeptides were sequenced with post-source decay (PSD) matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry for detecting phosphorylation sites. The charge of derivatization by 4-sulfophenyl isothiocyanate introduces a negative sulfonic acid group at the N-terminus of a peptide, and enables the selective detection of only a single series of C-terminal y-type ions. This chemically assisted method greatly simplifies the extremely complex pattern of PSD fragment ions and makes the PSD spectra more easier to be interpreted. The phosphorylation sites of a synthesized model phosphopeptide and human c-myc protein have been successfully identified by this method.     

Preparation of modified SiO2 colloidal spheres with succinic acid and the assembly of colloidal crystals

SiO2 colloidal spheres were synthesized by St-ber method. In order to enhance surface charge of the SiO2 spheres, they were modified with succinic acid. Scanning electron microscope (SEM) shows that the average size of modified SiO2 spheres is 473 nm, and its distribution standard deviation is less than 5%; Fourier-transform infrared spectra (FT-IR) and X-ray photoelectron spectrometer (XPS) results indicate that one end of succinic acid is chemically bonded to the SiO2 spheres through esterification; Zeta potential of the modified SiO2 spheres in water solution is improved from -53.72 to -67.46 mV, and surface charge density of the modified SiO2 spheres is enhanced from 0.19 to 0.94 μC/cm2. SiO2 colloidal crystal was fabricated from aqueous colloidal solution by the vertical deposition method at 40℃ and 60% relative humidity. SEM images show that the sample of SiO2 colloidal crystal is face-centered cubic (fcc) structure with its (111) planes parallel to the substrate. Transmission measurement shows the existence of photonic band gap at 1047 nm.     

Microwave assisted synthesis &; properties of nano HA-TCP biphasic calcium phosphate

Biphasic calcium phosphate (BCP) nanopowders were synthesized by using microwave and non-microwave irradiation assisted processes. The synthesized powders were pressed under a pressure of 90 MPa, and then were sintered at 1000-1200℃ for 1 h. The mechanical properties of the samples were investigated. The formed phases and microstructures were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results showed that the synthesis time was shorter, along with a more homogeneous microstructure, when the microwave irradiation assisted method was applied. The compression strength and the Young's modulus of the samples synthesized with microwave irradiation were about 60 MPa and 3 GPa, but those of the samples synthesized without microwave irradiation were about 30 MPa and 2 GPa, respectively. XRD patterns of the microwave irradiation assisted and non-microwave irradiation assisted nanopowders showed the coexistence of hydroxyapatite (HA) and tricalcium phosphate (TCP) phases in the system.     

半乳糖-聚乙二醇-聚-L-赖氨酸共聚物的制备与分析

 将相对分子质量为4 000的聚乙二醇中活性较弱的羟基转化为氨基,利用乳糖分子中含有半缩醛结构,可与双端氨基聚乙二醇（AT-PEG）分子中的伯氨基形成Schiff 碱,然后在氰基硼氢化钠作用下选择性还原为稳定的C-N 单键,使半乳糖连接在PEG的一个氨基上,合成半乳糖-单端氨基聚乙二醇（Gal-PEG-NH₂）,以Gal-PEG-NH₂为大分子引发剂,引发N^ε-苄氧羰基-L- 赖氨酸-N-羧酸酐［Lys(Z) NCA］开环聚合制备一系列半乳-糖-聚乙二醇-聚-L-赖氨酸（PLL-PEG-Gal）嵌段共聚物,通过调节Lys(Z) NCA和 Gal-PEG-NH₂的摩尔比例（［A］/［I］）可控制聚合物的相对分子质量。利用IR、¹³C-NMR、UV等方法进行共聚物结构分析,并对其接糖率进行了分析。结果表明,乳糖与双端氨基聚乙二醇反应生成的带有一侧氨基的聚乙二醇能引发Lys(Z) NCA 聚合生成Gal-PEG-PLL,其中半乳糖的接入率为8.3%。随着［A］/［I］的增加,共聚物的相对分子质量变大。     

CaSnO_3/膨润土复合光催化剂的制备及对亚甲基蓝的光催化降解性能

采用水热合成法制备出CaSnO3/膨润土复合光催化剂,采用XRD、SEM和IR等分析手段对该样品的形貌和结构进行表征,并研究了其对亚甲基蓝水溶液的光催化降解性能.结果表明:负载比例为3%的CaSnO3/膨润土复合光催化剂对亚甲基蓝水溶液的降解效果最好,当催化剂用量为60 mg,反应时间为14 min时,降解率可达98%.     

Synthesis of N-acetamide C60 nitride and its performance of optical limiting

N-acetamide C60 nitride (N-acetamide-1,2-dihydro-1,2-aza-fullerene[60]) has been synthesized by the reaction of C60 and azidoacetamide and initially characterized. Its mechanism was that the objective product is formed through intermediate triazoline. The computational study shows that N-nitride structure is thermodynamically more stable by using the semi-empirical AM1 SCF-MO method. The properties of optical limiting were tested by using double frequency Nd∶YAG pulse laser system and showed that the optical limiting mechanism is reverse saturation absorption. A wavelength of 532 nm, compared with optical limiting for ns pulse, this new material has good optical limiting character for ps pulse. At wavelength of 707 nm, the capacity of optical limiting of the derivative is prior to C60.     

水溶性C60-脱氢枞胺衍生物的合成及生物活性

以C60-脱氢枞胺吡咯烷衍生物和C60-脱氢枞胺氮烯加成物为原料,通过两种不同的水性化途径分别合成了两种水溶性的C60-脱氢枞胺富勒醇衍生物和两种水溶性的C60-脱氢枞胺甘氨酸衍生物。产物经TEM、FT-IR、ESI-MS、1H NMR和HPLC等分析方法检测确认为目标产物,且为加成度不同的混合物。对合成出的4种水溶性C60-脱氢枞胺衍生物进行了生物活性测试。结果表明,4种水溶性C60-脱氢枞胺衍生物对rTaq DNA聚合酶和HIV-1反转录酶均表现出一定的抑制作用,对卵巢癌细胞株几乎不表现出抑制活性。