This paper choose the static data of the typical well group of No.1 oil recovery plant in Daqing oilfield, apply ECLIPSE numerical simulator software, quantitatively compare the effect of three kinds of inhomogeneity to development index of polymer flooding (vertically interformational, vertically intraformational and areal heterogeneity). The research result shows that, the effect of three kinds of inhomogeneity to polymer flooding really exists and are different, of which the effect of vertically interformational heterogeneity is biggest, when the coefficient of permeability variation is between 0.6 and 0.8, the effect of polymer flooding is better; vertically intraformational heterogeneity display on the stability of barrier bed, of which the upper barrier bed is continuous, the effect of polymer flooding is better, the underlayer influence not too; the effect of areal heterogeneity present diversification.