In order to mutual interference between the study of vertical axis wind turbine blade and the center of the cylindrical tower, this paper to Sandia Darrieus wind turbine as the research object, the establishment of two-dimensional model, spalart allmaras turbulence model based on, on a three bladed Sandia Darrieus wind turbine in four different settings, numerical simulations are carried out in many cases, research and analysis, two-dimensional physical characteristics of blade and round tower interfere with each other, the blade suction surface pressure area the size of the change, the blade surface pressure distribution law of the change and influence of cylindrical tower of lift and drag coefficients. Results to reveal the physical mechanism of the vertical axis wind turbine wake, optimize the structure of wind turbine, wind turbine gas aeroelastic stability and reduce noise radiation has important theoretical value.