Three different types of medical waste latex gloves,cotton,infusion were selected as raw material and high temperature steam was selected as the gasifying agent in this paper. The impact of the variety of raw materials, gasification temperature, amount of water vapor flux into the production of components on gas, low calorific value were analyzed by the minimization of Gibbs free energy to simulate three kinds of raw material gasifying with the high temperature steam respectively. The results showed that at the same operating conditions,the content of hydrogen and oxygen control the hydrogen and carbon oxide production respectively,Gas low calorific value and the products will changed by changing the water vapor Medical waste mass ratio (S/W ratio) and temperature. It is concluded that the optimal reaction temperature is 800℃ and the optimal water vapor Medical waste mass ratio (S/W ratio) is 2.0.