As the main load-bearing structure，wing box is one of the main optimization objects which has great potential of weight reduction. During sizing-optimization for the wing box, static strength and globe deformation are focused on, and the other constrains are generally not taken into consideration due to the computing efficiency or technical maturation, which will induce that the optimization results can not meet with the requirements of rigidity or flutter. In this paper, a local rigidity response coupled with structure parameters is established to provide a direct rigidity constrain in the process of sizing-optimization by Hyperworks script developing.