Base on the detail investigation, find out the geotechnical engineering geological condition of the slope of Nanjing Qixia oil depot, adopt vertical stripe and oblique stripe two kinds of slope stable analysis methods to do the stability analysis research, find out the depth of potential sliding plan. Through the indoor test for the physical and mechanical parameters of the slope rock soil mass, and use the parameters to calculate the safety factor of unstable sliding plan, and comprehensive evaluate the stability of the sliding plan. Above all the basis, put forward the treatment measure of the stability.